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Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

UNC School of Medicine researcher Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen lab, have made a new discovery about apolipoprotein E (APOE) – the biggest genetic risk factor for late-onset Alzheimer's disease.

9 Feb 2024

Sleep apnea prevalent among cardio-oncology patients, study shows

Sleep apnea is prevalent among cardio-oncology patients who are at higher risk for congestive heart failure from cancer therapy, according to a new study being presented at the American College of Cardiology (ACC) Advancing the Cardiovascular Care of the Oncology Patient course.

9 Feb 2024

LSHTM researchers receive £2m funding to develop novel vaccines, diagnostics and therapeutics

Researchers from the London School of Hygiene & Tropical Medicine (LSHTM) have been awarded £2m funding through the UK Research and Innovation's (UKRI) Technology Missions Fund, to develop novel vaccines, diagnostics and therapeutics.

9 Feb 2024

AI tool maps protein function in tumors, paving way for personalized cancer treatment

Scientists have developed a new AI tool that maps the function of proteins in a cancerous tumor, enabling clinicians to decide how to target treatment in a more precise way.

9 Feb 2024

DDT exposure found to alter sperm epigenome in humans

In a study that signals potential reproductive and health complications in humans, now and for future generations, researchers from McGill University, the University of Pretoria, Université Laval, Aarhus University, and the University of Copenhagen, have concluded that fathers exposed to environmental toxins, notably DDT, may produce sperm with health consequences for their children.

9 Feb 2024

CARB-X awards $1.8 million to Visby Medical to develop a portable rapid PCR test for gonorrhea

Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) will award up to US$1.8 million to biotechnology company, Visby Medical, to develop a portable rapid polymerase chain reaction (PCR) diagnostic to detect the presence of the pathogen that causes gonorrhea, Neisseria gonorrhoeae (NG), and its susceptibility to ciprofloxacin, a former frontline oral antibiotic that can no longer treat resistant NG.

9 Feb 2024

Aspen Biosciences launches Pipeline, the program management software platform specifically for drug discovery. The groundbreaking ‘Pipeline’ Platform is now available for therapeutics development teams

Aspen Biosciences, a leading provider of custom software, and integrations for drug discovery companies, is excited to announce the launch of Pipeline, the drug discovery program management software platform.

9 Feb 2024

New mouse model illuminates lung cancer's transformation into aggressive variant

Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment.

8 Feb 2024

Multi-level network analysis provides integrated view of multiple sclerosis

International research led by the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University, in collaboration with Hospital del Mar, Hospital Clínic, Charité - Medical University of Berlin, and the universities of Oslo and Genoa, has developed a computational biology tool, based on multi-level network analysis, to achieve an integrated vision of multiple sclerosis.

8 Feb 2024

Mitochondrial misfire sparks inflammation

Cells in the human body contain power-generating mitochondria, each with their own mtDNA-;a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy.

8 Feb 2024

ELRIG UK announces Steve Bates and Dr Anderson Ryan as keynote speakers at Research and Innovation 2024

The European Laboratory Research & Innovation Group (ELRIG) UK today announced the keynote speakers for its upcoming Research and Innovation conference taking place at the University of Manchester from 20–21 March.

From ELRIG (UK) Ltd. 8 Feb 2024

New treatment target found for CDKL5 deficiency disorder

Scientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most common types of genetic epilepsy.

7 Feb 2024

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

AMG 133, an engineered bispecific molecule, demonstrated significant weight loss with a favorable safety profile in a phase 1 clinical trial, offering a promising new treatment option for obesity.

7 Feb 2024

Experimental mRNA vaccine against CMV elicits promising immune responses

An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, according to a study by Weill Cornell Medicine investigators.

7 Feb 2024

Researchers identify a new approach to controlling bacterial infections

Researchers at the Icahn School of Medicine at Mount Sinai have identified a new approach to controlling bacterial infections.

7 Feb 2024

Promising influenza drug candidate shows activity against resistant variants

Influenza A viruses with induced resistance to a new candidate antiviral drug were found to be impaired in cell culture and weakened in animals, according to a study by researchers in the Center for Translational Antiviral Research at Georgia State University.

6 Feb 2024

New cell therapy shows promise for critically ill COVID-19 patients with ARDS

Promising trial results indicate that a new type of cell therapy could improve the prognosis of those who are critically ill with acute respiratory distress syndrome (ARDS) resulting from severe Covid-19.

6 Feb 2024

Unraveling the architecture of poxvirus cores

A recent re-emergence and outbreak of Mpox brought poxviruses back as a public health threat, underlining an important knowledge gap at their core.

6 Feb 2024

Scientists pinpoint two cell-surface proteins that partner to spur cancer cell growth

Scientists at City of Hope®, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells' ability to cause disease. The study was published in Nature Structural & Molecular Biology today.

5 Feb 2024

Clinique and Mount Sinai partner to establish the Mount Sinai-Clinique Healthy Skin Dermatology Center

Clinique and Icahn School of Medicine at Mount Sinai today announced a philanthropic partnership to establish the Mount Sinai-Clinique Healthy Skin Dermatology Center.

5 Feb 2024

Therapeutics News and Research

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

Sleep apnea prevalent among cardio-oncology patients, study shows

LSHTM researchers receive £2m funding to develop novel vaccines, diagnostics and therapeutics

AI tool maps protein function in tumors, paving way for personalized cancer treatment

DDT exposure found to alter sperm epigenome in humans

CARB-X awards $1.8 million to Visby Medical to develop a portable rapid PCR test for gonorrhea

Aspen Biosciences launches Pipeline, the program management software platform specifically for drug discovery. The groundbreaking ‘Pipeline’ Platform is now available for therapeutics development teams

New mouse model illuminates lung cancer's transformation into aggressive variant

Multi-level network analysis provides integrated view of multiple sclerosis

Mitochondrial misfire sparks inflammation

ELRIG UK announces Steve Bates and Dr Anderson Ryan as keynote speakers at Research and Innovation 2024

New treatment target found for CDKL5 deficiency disorder

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

Experimental mRNA vaccine against CMV elicits promising immune responses

Researchers identify a new approach to controlling bacterial infections

Promising influenza drug candidate shows activity against resistant variants

New cell therapy shows promise for critically ill COVID-19 patients with ARDS

Unraveling the architecture of poxvirus cores

Scientists pinpoint two cell-surface proteins that partner to spur cancer cell growth

Clinique and Mount Sinai partner to establish the Mount Sinai-Clinique Healthy Skin Dermatology Center

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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