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BCG vaccine's impact on innate immunity explained at cellular level

Bacillus Calmette-Guérin (BCG) is one of the world’s oldest and most widely used vaccines. It was developed in the early 20th century to provide protection from tuberculosis.

9 Jan 2024

SickKids scientists untangle cellular waste buildup in Zellweger Spectrum Disorder

For the first time, a research team at The Hospital for Sick Children (SickKids) has uncovered a way to potentially reduce the amount of toxic cellular waste accumulating in patients with Zellweger Spectrum Disorder (ZSD).

9 Jan 2024

Marking a vital milestone for Vertex and Charles River

Charles River’s Memphis facility approved to manufacture Vertex’s CASGEVY™ therapy, the world’s first gene-edited therapy targeting severe sickle cell disease

From Charles River 9 Jan 2024

Cellular Origins, a TTP Company, establishes Advisory Board of global industry leaders

Renowned experts from across the CGT and robotics industries, Professor John Campbell, Dr Matthew Li, Dr Paul Roberts, and Geoffrey Hodge appointed to provide strategic and technical perspectives.

From Cellular Origins 9 Jan 2024

Research potentially expands options for patients with aggressive childhood cancer

Research is shedding light and potentially expanding options for patients living with Medulloblastoma, an aggressive childhood cancer.

8 Jan 2024

New test detects Parkinson's disease before symptoms appear

In the development of Parkinson's disease (PD), the changes that will lead to neurodegeneration take place in the brain long before patients show any symptoms.

8 Jan 2024

New peptide library paves the way for targeting elusive cancer factor MYC

Researchers developed a second-generation NTB bicyclic peptide library, identifying NT-B2R, a peptide that effectively targets MYC, a key factor in most human cancers, demonstrating its potential in inhibiting MYC transcription activities and cancer cell proliferation.

8 Jan 2024

Combining immunotherapy and radiation to tackle aggressive triple-negative breast cancer

Cedars-Sinai Cancer investigators have analyzed the cells within triple-negative breast cancer tumors before and after radiation therapy with immunotherapy, identifying three patient groups with different responses to the treatment.

8 Jan 2024

Engineered virus-like particles power up gene editing, correcting blindness in mice

Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals.

8 Jan 2024

COMPANION study of digital therapy demonstrates reduced anxiety in patients with pulmonary fibrosis

Vicore Pharma Holding AB (publ), unlocking the potential of a new class of drug candidates, angiotensin II type 2 receptor agonists (ATRAGs), today announced positive results of the COMPANION study (NCT05330312), investigating the efficacy of AlmeeTM, a 9-week digital cognitive behavioral therapy (CBT) accessed through a smartphone or tablet.

8 Jan 2024

Digital CBT intervention reduces anxiety and improves quality of life for pulmonary fibrosis patients

Alex Therapeutics and Vicore Pharma today announced positive results of the COMPANION study, investigating the efficacy of Almee, a 9-week digital cognitive behavioral therapy (CBT) intervention accessed through a smartphone or tablet.

8 Jan 2024

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

Scientists at St. Jude Children's Research Hospital are tackling Mycobacterium abscessus (Mab) antibiotic resistance.

5 Jan 2024

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

5 Jan 2024

IKAROS: Unlocking the secrets of the immune system's key player

In a scientific breakthrough that aids our understanding of the internal wiring of immune cells, researchers at Monash University in Australia have cracked the code behind IKAROS, an essential protein for immune cell development and protection against pathogens and cancer.

5 Jan 2024

ATCC announces new award from BARDA to provide centralized storage and bioprocessing services for Project NextGen

ATCC, the world’s premier biological materials management and standards organization, today announced a five-year, $87 million award from the Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response within the U.S. Department of Health and Human Services, to support the development of next-generation medical countermeasures (MCMs) to protect Americans from public health security threats such as coronaviruses.

From ATCC 5 Jan 2024

Researchers harness the power of AI to enhance assessment of the heart's right ventricle

In a milestone study, researchers from the Icahn School of Medicine at Mount Sinai have harnessed the power of artificial intelligence (AI) to enhance the assessment of the heart's right ventricle, which sends blood to the lungs.

4 Jan 2024

Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins-;and ultimately affect aging.

4 Jan 2024

Therapeutics News and Research

BCG vaccine's impact on innate immunity explained at cellular level

SickKids scientists untangle cellular waste buildup in Zellweger Spectrum Disorder

Marking a vital milestone for Vertex and Charles River

Cellular Origins, a TTP Company, establishes Advisory Board of global industry leaders

Research potentially expands options for patients with aggressive childhood cancer

New test detects Parkinson's disease before symptoms appear

New peptide library paves the way for targeting elusive cancer factor MYC

Combining immunotherapy and radiation to tackle aggressive triple-negative breast cancer

Engineered virus-like particles power up gene editing, correcting blindness in mice

COMPANION study of digital therapy demonstrates reduced anxiety in patients with pulmonary fibrosis

Digital CBT intervention reduces anxiety and improves quality of life for pulmonary fibrosis patients

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

Stapled lipopeptides show promise as broad-spectrum antiviral agents

IKAROS: Unlocking the secrets of the immune system's key player

ATCC announces new award from BARDA to provide centralized storage and bioprocessing services for Project NextGen

Researchers harness the power of AI to enhance assessment of the heart's right ventricle

Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Salk scientists map brain circuit triggering the crippling panic attacks

Combination therapy of dapagliflozin and semaglutide shows superior efficacy in type 2 diabetes management

Simple technique boosts antibody delivery for treating brain diseases

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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