Therapeutics News and Research

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Lab study shows THC exposure as adolescents linked to negative effects of THC as adults

In earlier studies, researchers at Louisiana State University had found that estrogen - or more precisely, having ovaries - made adult rats exposed for the first time to THC, the primary ingredient in marijuana and hashish, less sensitive to THC's negative effects on tests of learning and memory.

20 Apr 2009

Federal funding for partnership to combat infectious diseases

Oregon Health & Science University and the University of Washington, along with a number of partner institutions across the Northwest, have received federal funding to form a regional research center aimed at combating emerging or re-emerging infectious diseases that pose a serious threat to human health.

15 Apr 2009

Experimental insulin-like growth factor receptor inhibitor a clear clinical candidate for pancreatic cancer therapy

Researchers at Amgen are testing a fully human monoclonal antibody that inhibits the activity of insulin-like growth factors (IGF-1 and IGF-2) and appears to reduce pancreatic cancer cells in early testing, according to a report in Molecular Cancer Therapeutics, a journal of the American Association for Cancer Research.

14 Apr 2009

New small molecule approach to Alzheimer's disease treatment

New therapeutic approaches in Alzheimer's disease are urgently needed.

13 Apr 2009

Tolera Therapeutics granted orphan drug status for organ transplant rejection lead candidate drug

Tolera Therapeutics, Inc., was granted orphan drug status by the United States Food and Drug Administration (FDA) for its initial lead candidate, TOL101, for prophylaxis of acute rejection of solid organ transplantation.

12 Apr 2009

New alternative to biopsy detects subtle changes in cancer cells

A drop of blood or a chunk of tissue smaller than the period at the end of this sentence may one day be all that is necessary to diagnose cancers and assess their response to treatment, say researchers at the Stanford University School of Medicine.

12 Apr 2009

BioDuro and Roche enter into strategic collaboration to provide drug discovery services

BioDuro has announced that they have entered into a strategic partnership with Roche to support discovery phase research efforts at Roche's global research sites.

6 Apr 2009

Breakthrough for hypertension treatment

A world-first breakthrough to treat high blood pressure has been successfully trialled in Melbourne.

6 Apr 2009

Monoclonal antibody cancer therapy

The strategy of using monoclonal antibodies for cancer treatment was first described in the late 1970s with the promise that they could be developed into therapies that were highly specific to cancer cells, killing them with few or no side effects.

6 Apr 2009

Locking parasites in host cell could be new way to fight malaria

Researchers at the University of Pennsylvania have discovered that parasites hijack host-cell proteins to ensure their survival and proliferation, suggesting new ways to control the diseases they cause.

6 Apr 2009

Cytori receives U.S. patent allowance for key therapeutic methods for breast and soft tissue reconstruction products

Cytori Therapeutics, Inc. received a Notice of Allowance from the U.S. Patent and Trademark Office for a patent application that protects key therapeutic methods for its breast and soft tissue reconstruction products. This patent will protect Cytori's existing and future products when sold in the U.S.

31 Mar 2009

ImQuest presents data on the anti-hepatitis B virus activity of Pyrimidinediones

ImQuest Life Sciences today presented important new results on the continued development of the pyrimidinedione small molecules as antiviral agents at the 13th International Symposium on Viral Hepatitis and Liver Disease meeting held last week in Washington D.C.

31 Mar 2009

Nile Therapeutics update on phase II CD-NP trial for acute heart failure

Nile Therapeutics, Inc. has announced that, in the course of reviewing the Investigational New Drug (IND) application materials that Nile submitted to the U.S. Food and Drug Administration (FDA) to support the initiation of the Company's Phase IIb clinical trial with CD-NP for the treatment of acute heart failure, the FDA has placed CD-NP on clinical hold.

30 Mar 2009

Amicus Therapeutics presents positive results from phase 2 extension study of Amigal for Fabry disease

Amicus Therapeutics has announced positive results from its ongoing Phase 2 extension study of its investigational drug, Amigal (migalastat HCL) for Fabry disease.

29 Mar 2009

Scientists discover structure of a protein that makes cancer cells resistant to chemotherapy

A research team at the Scripps Research Institute has obtained the first glimpse of a protein that keeps certain substances, including many drugs, out of cells.

29 Mar 2009

Rexahn Pharmaceuticals starts phase II pancreatic cancer trial

Rexahn Pharmaceuticals, Inc. has announced that it has received FDA approval to begin Phase II trials for Archexin, the Company's leading cancer compound, for the treatment of pancreatic cancer.

24 Mar 2009

Gilead commences phase II trial of Cicletanine for pulmonary arterial hypertension

Gilead Sciences, Inc. has announced that it has begun enrolling patients in a Phase II clinical trial of cicletanine hydrochloride (cicletanine), an oral agent in development for the treatment of pulmonary arterial hypertension (PAH).

24 Mar 2009

Experimental Parkinson's therapy may have robust weight-loss effect

A growth factor used in clinical experiments to rescue dying brain cells in Parkinson patients may cause unwanted weight loss if delivered to specific areas of the brain, according to University of Florida researchers in the March online edition of Molecular Therapy.

24 Mar 2009

Astrocytes help separate man from mouse

A type of brain cell that was long overlooked by researchers embodies one of very few ways in which the human brain differs fundamentally from that of a mouse or rat, according to researchers who published their findings as the cover story in the March 11 issue of the Journal of Neuroscience.

23 Mar 2009

Research yields potential target for cancer, wound healing and fibrosis

Research conducted by Allison Berrier, PhD, Assistant Professor of Oral and Craniofacial Biology at the LSU Health Sciences Center New Orleans School of Dentistry, and colleagues, provides insights that may help scientists design novel approaches to control wound healing and fight diseases such as cancer and fibrosis.

20 Mar 2009

Therapeutics News and Research

Lab study shows THC exposure as adolescents linked to negative effects of THC as adults

Federal funding for partnership to combat infectious diseases

Experimental insulin-like growth factor receptor inhibitor a clear clinical candidate for pancreatic cancer therapy

New small molecule approach to Alzheimer's disease treatment

Tolera Therapeutics granted orphan drug status for organ transplant rejection lead candidate drug

New alternative to biopsy detects subtle changes in cancer cells

BioDuro and Roche enter into strategic collaboration to provide drug discovery services

Breakthrough for hypertension treatment

Monoclonal antibody cancer therapy

Locking parasites in host cell could be new way to fight malaria

Cytori receives U.S. patent allowance for key therapeutic methods for breast and soft tissue reconstruction products

ImQuest presents data on the anti-hepatitis B virus activity of Pyrimidinediones

Nile Therapeutics update on phase II CD-NP trial for acute heart failure

Amicus Therapeutics presents positive results from phase 2 extension study of Amigal for Fabry disease

Scientists discover structure of a protein that makes cancer cells resistant to chemotherapy

Rexahn Pharmaceuticals starts phase II pancreatic cancer trial

Gilead commences phase II trial of Cicletanine for pulmonary arterial hypertension

Experimental Parkinson's therapy may have robust weight-loss effect

Astrocytes help separate man from mouse

Research yields potential target for cancer, wound healing and fibrosis

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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