Thrombus News and Research

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A blood clot or thrombus, is the final product of the blood coagulation step in hemostasis. It is achieved via the aggregation of platelets that form a platelet plug, and the activation of the humoral coagulation system (i.e. clotting factors).

Study aims to optimize device implantation in patients with atrial fibrillation and stroke risk

According to clinical studies, about a third of patients with atrial fibrillation will suffer a stroke during their lifetime. Between 70 and 90% of these strokes are caused by a thrombus formed in the left atrial appendage.

16 May 2019

Renal infarction linked with acute kidney injury in patients with cardiac amyloidosis

Systemic amyloidosis is a major cause of renal injury, mostly due to direct kidney damage caused by deposits of abnormal protein called amyloid, in the kidney parenchyma.

16 May 2019

Imaging beyond routine angiography may be helpful in women with suspected MI and no obstructive CAD

A subset of women referred to the cardiac catheterization lab for suspected myocardial infarction thought to be due to a culprit artery are found to have no obstructive coronary artery disease by angiography.

9 May 2019

Scientists solve mystery surrounding mechanical forces that influence blood clotting

Researchers at the University of Sydney have used biomechanical engineering techniques to unlock the mystery surrounding the mechanical forces that influence blood clotting.

5 Apr 2019

Russian researchers propose new approach for prevention of thrombosis

A new approach for the prevention of thrombosis was proposed by researchers from the Moscow Institute of Physics and Technology and the Russian National Research Center for Hematology.

7 Mar 2019

New PET/CT tracer shows high detection rate for diagnosis of acute venous thromboembolism

A first-in-human study featured in the February issue of The Journal of Nuclear Medicine reports that the novel positron emission tomography/computed tomography tracer 18F-GP1 showed excellent image quality and a high detection rate for the diagnosis of acute venous thromboembolism.

18 Feb 2019

Validation of non-invasive stent monitoring techniques

Researchers from the Research Institute Germans Trias i Pujol, the Biomedical Research Networking Center on Cardiovascular Diseases, the University of Barcelona and the the Universitat Politècnica de Catalunya have created a new field probe to detect in a non-invasive and non-ionizing way the presence of metallic stents as well as their potential structural failures through microwave spectrometry.

25 Oct 2018

Infants face high thrombosis risk

Russian scientists have carried out tests to compare the process of blood coagulation in adults and newborns and discovered that the latter face an increased risk of thrombosis.

1 Oct 2018

Researchers highlight potential therapy for treating rare, deadly blood-clotting disorder

In proof-of-concept experiments, University of Alabama at Birmingham researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP.

24 Sep 2018

UCalgary study could help physicians make better treatment decisions for stroke

More than 80 percent of strokes are caused when a blood vessel to the brain becomes blocked, called an ischemic stroke.

19 Sep 2018

Penumbra introduces new advancements in stroke thrombectomy aspiration technology

Penumbra, Inc., a global healthcare company focused on innovative therapies, today announced U.S. commercial availability of the Penumbra System's most advanced technology: Penumbra JET 7 and Penumbra JET D Reperfusion Catheters powered by the Penumbra ENGINE aspiration source.

4 Sep 2018

Study: Potential new class of drugs may lower heart disease risk by targeting gut microbes

Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut.

7 Aug 2018

Researchers develop drug-delivery system that allows rapid response to heart attacks

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a drug-delivery system that allows rapid response to heart attacks without surgical intervention.

7 Aug 2018

CERENOVUS announces launch of novel stent retriever for treating stroke patients

CERENOVUS, part of the Johnson & Johnson Medical Devices Companies, announced the first patients have been treated with its new EMBOTRAP II Revascularization Device since it became commercially available in the U.S. EMBOTRAP II is a next-generation stent retriever used to capture and remove life-threatening blood clots from the brain following an ischemic stroke.

26 Jul 2018

Mechanical thrombectomy appears to be important therapy for acute stroke in very old patients

The mechanical removal of blood clots in acute stroke is highly effective but not suitable for all patients.

18 Jun 2018

Powerful clot-busting drugs reserved for selected patients with deep vein thrombosis

Not all patients with blood clots in their legs – a condition known as deep vein thrombosis – need to receive powerful but risky clot-busting drugs, according to results of a large-scale, multicenter clinical trial.

7 Dec 2017

Discovery of natural molecule could lead to effective treatments for gum disease and atherosclerosis

Resolvin E1, a molecule produced naturally in the body from an omega -3 fish oil, topically applied on gum tissues not only prevents and treats gum disease as previously shown (Hasturk et al 2006 and 2007), but also decreases the likelihood for advanced arterial atherosclerotic plaques to rupture and form a dangerous thrombus or blood clot.

16 Nov 2017

High level of heart disease pipeline innovation could bridge unmet need in treating CVD

With over 1,400 products in active development, the innovation pipeline for cardiovascular disease (CVD) is extensive, with four key CVD indications – hypertension, heart failure, dyslipidemia and thrombosis – now accounting for around half of all pipeline innovation, according to GBI Research, a recognized leader in providing business information and analytics.

24 Aug 2017

Novel small molecule tracer for PET imaging spots blood clots

Blood clots in veins and arteries can lead to heart attack, stroke, and pulmonary embolism, which are major causes of mortality.

6 Jul 2017

CWRU researcher receives major NIH grants to develop microscopic drug-delivery systems

Nicole F. Steinmetz, PhD, George J. Picha Professor in Biomaterials, member of the Case Comprehensive Cancer Center, and Director of the Center for Bio-Nanotechnology at Case Western Reserve School of Medicine, has received two major grants from the National Institutes of Health to develop microscopic drug-delivery systems for patients living with breast cancer, and patients at risk for serious blood clots.

29 Jun 2017