Toxin News and Research

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New methods for revealing nerve-muscle activity in live animals

Picking up a pencil, running a marathon, even the simple act of breathing - every time we move a muscle we depend on a series of finely-tuned interactions at the junction of nerve fiber and muscle cell.

20 Apr 2006

Researchers improve Botox treatment

There may soon be a better way to fight unsightly wrinkles. Researchers have discovered a novel way to increase the potency of botulinum neurotoxin treatments - commonly known as Botox - that they say could one day allow patients to receive the injections less frequently while maintaining or even enhancing its cosmetic benefits.

7 Apr 2006

Link between lead and osteoporosis strengthens

Bolstered by recent laboratory findings, researchers at the University of Rochester Medical Center are embarking on a National Institutes of Health-funded clinical study to better understand the deceptive role environmental lead exposure plays in bone maturation and loss.

4 Apr 2006

Proteomics yields new drug targets for treating cardiogenic shock

When it comes to cell signaling and bioregulation, it's tough to find a more important molecule than nitric oxide (NO). Dysfunction of NO-mediated signaling is thought to be a culprit in lethal cardiovascular conditions such as angina, and septic, cardiogenic and hemorrhagic shock; it may play a role in many other illnesses as well.

3 Apr 2006

Discovery of a gene that drives anthrax bacteria's toxic effects

A study in Cell reports the discovery of a gene that drives anthrax bacteria's toxic effects. The gene could offer a potential new target for countermeasures against the lethal toxin, according to the researchers.

28 Mar 2006

Poor children at greater risk for exposure to toxic pollutants

Poor and ethnic minority children in the United States have a significantly greater risk for exposure to toxic pollutants that can affect their cognitive development and other health indicators than higher income and non-minority peers, and current local, state and federal policies appear to be failing to address these inequities.

23 Mar 2006

Researcher identifies the cellular receptor for botulinum neurotoxin A

Botulinum neurotoxin A can be either the greatest wrinkle remover or one of the world's most potent biological weapons. To perform either job, however, the toxin must first find a way to enter cells.

20 Mar 2006

Hospitalized schizophrenics more likely to have complications

A Johns Hopkins study of more than 1,700 patients with schizophrenia hospitalized for medical or surgical care unrelated to their mental disorder shows they are at least twice as likely as similar patients without schizophrenia to suffer dangerous and expensive adverse events.

15 Mar 2006

Exposure to toxins from hazardous waste sites may be a significant risk factor for developing primary biliary cirrhosis

Published in the March 2006 issue of Hepatology, researchers found significant clusters of the disease near Superfund toxic waste sites (SFS) and that the majority of patients in New York City who need liver transplants because of PBC, reside near SFS.

13 Mar 2006

Taipan venom may stop excessive bleeding during vascular surgery

A blood-clotting protein in taipan venom has been identified by Queensland University of Technology PhD researcher Liam St Pierre to rapidly stop excessive bleeding during vascular surgery and major trauma.

9 Mar 2006

New compound CDDO-Im protects against the development of liver cancer

Researchers have identified a new compound called CDDO-Im that protects against the development of liver cancer in laboratory animals.

17 Feb 2006

Botox finds a use in cancer treatment

The cosmetic treatment Botox may have a new use as an adjuvant to cancer therapy, providing an open door for chemotherapy and radiation treatments, according to a study published in the Feb. 15 issue of Clinical Cancer Research.

17 Feb 2006

Vaccine against ricin safe and effective

Scientists at the University of Texas Southwestern Medical Center at Dallas, say a vaccine against the deadly toxin ricin is safe and effective.

31 Jan 2006

Cocaine abuse may increase risk of Parkinson's disease

Adults who abuse cocaine might increase their risk of developing Parkinson's disease (PD), and pregnant women who abuse cocaine could increase the risk of their children developing PD later in life, according to results of laboratory studies performed by investigators at St. Jude Children's Research Hospital.

13 Dec 2005

Botox - other applications

While botulinum toxin A, or BTXA, is widely known for its use in dermatology and aesthetic medicine, a review article in the Journal of Cosmetic Dermatology explores the drug’s other successful applications.

12 Dec 2005

New anthrax antibody

A new anthrax antibody engineered by scientists at The University of Texas at Austin protects and defends against inhalation anthrax without the use of antibiotics and other more expensive antibodies.

2 Dec 2005

EphA2 represents a promising treatment target for glioblastoma multiforme

Researchers at Wake Forest University Baptist Medical Center have identified a second promising treatment target for glioblastoma multiforme, one of the most deadly types of brain tumors. The research results are reported in the October issue of Molecular Cancer Research.

1 Nov 2005

Botox not just for glamour, great for stroke victims too

Botox, or botulinum toxin's, main claim to fame currently seems to be associated with stars and others who wish for fuller lips and ironed out wrinkles, but the treatment does in fact have a far more credible and worthwhile reputation which continues to grow.

1 Nov 2005

Scientists unravel complex mechanisms in the brain that regulate body weight

Scientists are one step closer to unraveling the complex mechanisms in the brain that regulate body weight. Working with mice -- whose appetites are controlled by systems very similar to those in humans – they have identified a specific type of neuron that is essential for feeding behavior.

30 Oct 2005

First long-term study to evaluate repeated treatment with BoNTA for post-stroke spasticity

New research shows that repeated treatments of botulinum toxin type A (BoNTA) over one year after a stroke can improve muscle tone and reduce pain in the arms and hands, making it easier for patients to dress themselves and perform personal hygiene.

30 Oct 2005