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A new technology to diagnose COVID-19 in just 30 minutes

The year 2020 can be summarized simply by one word - COVID-19 - as it was the culprit that froze the entire world. For more than 8 months so far, movement between nations has been paralyzed all because there are no means to prevent or treat the virus and the diagnosis takes long.

5 Oct 2020

Feasibility of using dry reagents LAMP assay for SARS-CoV-2 detection

In a new study published on the preprint server medRxiv, researchers evaluated the suitability of the Loopamp SARS-CoV-2 Detection kit from Eiken Chemica, Japan, for detecting SARS-CoV-2. This is a LAMP method that uses dry reagents for RNA amplification.

5 Oct 2020

AbC-19 blood test detects COVID-19 antibodies 20 weeks after first symptoms/PCR positive result

Serological antibody immunoassays are one of the essential tools to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In a new study, Immunoglobulin G (IgG) antibodies are detected in a large cohort, lasting up to 140 days. The researchers propose an alternative to reverse transcription-polymerase chain reaction (RT-PCR) positive status as a standard for assessing SARS-CoV-2 antibody assays and show robust performance metrics for the AbC-19 rapid test.

5 Oct 2020

Rapid detection of SARS-CoV-2 with portable CRISPR-based mobile phone diagnostic test

A large group of researchers from the United States reported developing an amplification-free CRISPR-based mobile phone assay for direct detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from nasal swabs. Their state-of-the-art paper is currently available on the medRxiv* preprint server.

4 Oct 2020

Identifying cardiopulmonary processes involved in severe COVID-19

Researchers in the United States have identified cardiopulmonary processes that may partly explain why some individuals with coronavirus disease 2019 (COVID-19) develop respiratory failure.

4 Oct 2020

Anti-sense agents suppress SARS-CoV-2 virus

Researchers in the United States have conducted a study showing that anti-sense agents called peptide-conjugated morpholino oligomers (PPMOs) have the ability to specifically and potently suppress the growth of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

4 Oct 2020

Scientists map genetic networks that control the biology of regulatory T cells

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

1 Oct 2020

23 SARS-CoV-2 strains circulating in the Philippines

In a new study published on the medRxiv* preprint server, scientists reported coding of complete genome sequences of 23 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains in the Philippines.

1 Oct 2020

AI can be nearly as accurate as a physician in diagnosing COVID-19

The new UCF co-developed algorithm can accurately identify COVID-19 cases, as well as distinguish them from influenza.

30 Sep 2020

A study contradicting the phenotypical relationship between plasmablasts and developing neutrophils

A team of scientists from Australia challenges the findings of a recent study by Wilk et al. demonstrating that plasmablasts transdifferentiate into developing neutrophils in severe coronavirus disease 2019 (COVID-19). The Australian study is currently available on the bioRxiv preprint server.

29 Sep 2020

Newly discovered genetic factor allows adult skin to regenerate like a newborn's

A newly identified genetic factor allows adult skin to repair itself like the skin of a newborn babe. The discovery by Washington State University researchers has implications for better skin wound treatment as well as preventing some of the aging process in skin.

29 Sep 2020

Researchers identify cells responsible for cardiac damage repair after infarction

Researchers at Cima and the Clinica Universidad de Navarra (Spain) have led an international study identifying the cardiac cells responsible for repairing the damage to this organ after infarction.

29 Sep 2020

SARS-CoV-2 re-infection is real but rare: Case study

Now, American researchers have looked at all reported cases of re-infection and the possible reasons behind them. Their study titled, “Re-infection with SARS-CoV-2 and Failure of Humoral Immunity: a case report,” is published online on the preprint server medRxiv in September 2020.

28 Sep 2020

Researchers discover specific cellular pathway involved in lung tissue regeneration

Researchers at Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries.

28 Sep 2020

Epigenetic changes in the brain drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

28 Sep 2020

Researchers decipher how the immune system memorizes pathogens after an infection

The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists at the University of Würzburg have deciphered new details of this process.

28 Sep 2020

Anti-N-protein IgG may predict severity of COVID-19

A recent study by researchers at the University of Miami, Miami VA Healthcare System and Express Gene and published on the preprint server medRxiv in September 2020 reports on the prognostic significance of the anti-N Immunoglobulin G (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Sep 2020

CRISPR screening identifies human host pathways that facilitate coronavirus infection

The human coronavirus family consists of 7 known pathogens, for which there are no approved vaccines or specific therapeutic options. Although the seasonal human coronaviruses - OC43, HKU1, 229E, and NL63 – only cause mild respiratory infections, three highly pathogenic coronaviruses that emerged in the last two decades revealed the pandemic potential of this family of viruses.

27 Sep 2020

Young adults now driving force behind the ongoing COVID-19 pandemic says CDC

The Centers for Disease Control and Prevention (CDC) has released a report stating that the ongoing COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is on the rise among young adults and this rise is preventing the pandemic from abating.

27 Sep 2020

New optical switch to precisely control the lifespan of genetic 'copies'

A novel optical switch makes it possible to precisely control the lifespan of genetic "copies". These are used by the cell as building instructions for the production of proteins.

25 Sep 2020

Transcription News and Research

A new technology to diagnose COVID-19 in just 30 minutes

Feasibility of using dry reagents LAMP assay for SARS-CoV-2 detection

AbC-19 blood test detects COVID-19 antibodies 20 weeks after first symptoms/PCR positive result

Rapid detection of SARS-CoV-2 with portable CRISPR-based mobile phone diagnostic test

Identifying cardiopulmonary processes involved in severe COVID-19

Anti-sense agents suppress SARS-CoV-2 virus

Scientists map genetic networks that control the biology of regulatory T cells

23 SARS-CoV-2 strains circulating in the Philippines

AI can be nearly as accurate as a physician in diagnosing COVID-19

A study contradicting the phenotypical relationship between plasmablasts and developing neutrophils

Newly discovered genetic factor allows adult skin to regenerate like a newborn's

Researchers identify cells responsible for cardiac damage repair after infarction

SARS-CoV-2 re-infection is real but rare: Case study

Researchers discover specific cellular pathway involved in lung tissue regeneration

Epigenetic changes in the brain drive late-onset Alzheimer's disease

Researchers decipher how the immune system memorizes pathogens after an infection

Anti-N-protein IgG may predict severity of COVID-19

CRISPR screening identifies human host pathways that facilitate coronavirus infection

Young adults now driving force behind the ongoing COVID-19 pandemic says CDC

New optical switch to precisely control the lifespan of genetic 'copies'

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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