Transcription News and Research

RSS

Study shows how regulatory mechanisms contribute to formation of tissues in mouse embryo

A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its "packaging"

5 Aug 2020

New method reveals the dynamics of cell development and gene activity

Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions - but they do this with static snapshots only rather than time-lapse films.

4 Aug 2020

Long stretches of repeating DNA associated with susceptibility to systemic sclerosis

Researchers from the University of Tsukuba show that long stretches of repeat DNA sequences in the gene FLI1 are associated with susceptibility to systemic sclerosis.

2 Aug 2020

Synthetic riboregulators detect SARS-CoV-2 genome parts in 40 minutes

By exploiting the tools of synthetic biology, the researchers from Turkey have successfully developed a de novo riboregulator system for rapidly detecting the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic material. Their paper is currently available on medRxiv preprint server.

2 Aug 2020

15 young scientists receive Damon Runyon Fellowship Award to pursue cancer research

Grants totaling nearly $3.5 million give early career investigators independence to pursue brave and bold cancer research.

31 Jul 2020

Managing cancer patients during COVID-19 pandemic

An ESMO interdisciplinary expert consensus paper on how to manage cancer patients during the COVID-19 pandemic has been published today in Annals of Oncology.

31 Jul 2020

Researchers identify targeted treatment strategy for malignant pleural mesothelioma

The reactivation of telomerase is a key mechanism in the unrestricted growth of cancer cells. Malignant pleural mesothelioma (MPM) is a form of cancer originating from the mesothelium, a cell layer covering the lungs and the inside of the chest wall.

30 Jul 2020

Study reports highly potent anti-SARS-CoV-2 compounds

A new study published on the preprint server bioRxiv in July 2020 reports that a series of potent enzyme inhibitors have been designed to suppress severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication by interfering with one of the primary viral proteases.

30 Jul 2020

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

In research that aims to illuminate the causes of human developmental disorders, Salk scientists have generated 168 new maps of chemical marks on strands of DNA--called methylation--in developing mice.

29 Jul 2020

Novel drug candidate offers a major advance in the treatment for diabetes

The University of Alabama at Birmingham and Southern Research have discovered a new drug candidate that offers a major advance in the treatment for diabetes.

28 Jul 2020

Alternative amplification technique could accelerate COVID-19 testing

An alternative amplification technique to detect SARS-CoV-2 RNA could offer a way to rapidly test large numbers of people for COVID-19, although the technique is not as sensitive as quantitative RT-PCR, the current standard method for COVID-19 testing.

27 Jul 2020

High ACE2 Expression on pancreatic islet cells during inflammation could explain new-onset diabetes in COVID-19

A new study suggests that the SARS-CoV-2 infection may be linked to the onset of diabetes, via the infection of pancreatic islet beta cells, which produce insulin.

27 Jul 2020

Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

A new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.

25 Jul 2020

Technology divide between senior ‘haves’ and ‘have-nots’ roils pandemic response

Family gatherings on Zoom and FaceTime. Online orders from grocery stores and pharmacies. Telehealth appointments with physicians.

24 Jul 2020

Epigenomic modifications play key role in the development of lung tumors

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

23 Jul 2020

Research could lead to more efficient cellular immunotherapies for advanced cancers

Adoptive cell transfer immunotherapy is one of the most promising new treatments for people with hard-to-treat cancers.

23 Jul 2020

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

As COVID-19 continues to spread over the world scientists continue to seek the reasons for the difference in disease severity from person to person.

22 Jul 2020

Researchers investigate the genetic and molecular basis of PD-L2 regulation

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs.

22 Jul 2020

Silver-plated gold nanostars could be used to identify early biomarkers of cancer

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

21 Jul 2020

Study may lead to new diagnostic and treatment strategies for fighting bone cancer

Osteosarcoma (OS) is the most common form of aggressive bone cancer. A MedUni Vienna study, led by geneticist Erwin Wagner, has uncovered new insights into the disease mechanisms of OS, paving the way for potential new diagnostic and treatment strategies for fighting the bone disease

21 Jul 2020

Transcription News and Research

Study shows how regulatory mechanisms contribute to formation of tissues in mouse embryo

New method reveals the dynamics of cell development and gene activity

Long stretches of repeating DNA associated with susceptibility to systemic sclerosis

Synthetic riboregulators detect SARS-CoV-2 genome parts in 40 minutes

15 young scientists receive Damon Runyon Fellowship Award to pursue cancer research

Managing cancer patients during COVID-19 pandemic

Researchers identify targeted treatment strategy for malignant pleural mesothelioma

Study reports highly potent anti-SARS-CoV-2 compounds

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

Novel drug candidate offers a major advance in the treatment for diabetes

Alternative amplification technique could accelerate COVID-19 testing

High ACE2 Expression on pancreatic islet cells during inflammation could explain new-onset diabetes in COVID-19

Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

Technology divide between senior ‘haves’ and ‘have-nots’ roils pandemic response

Epigenomic modifications play key role in the development of lung tumors

Research could lead to more efficient cellular immunotherapies for advanced cancers

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

Researchers investigate the genetic and molecular basis of PD-L2 regulation

Silver-plated gold nanostars could be used to identify early biomarkers of cancer

Study may lead to new diagnostic and treatment strategies for fighting bone cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News