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Scientists reprogram mature inhibitory neurons into dopaminergic cells

Attempting to make dopamine-producing neurons out of glial cells in mouse brains, a group of researchers instead converted mature inhibitory neurons into dopaminergic cells.

12 Oct 2018

Researchers develop organoid that functions as real salivary gland

Researchers have successfully used induced pluripotent stem cells to grow a 3D salivary gland tissue that produces saliva when implanted in mice.

11 Oct 2018

Scientists succeed in growing functional salivary gland

A research group led by scientists from Showa University and the RIKEN Center for Biosystems Dynamics Research in Japan have, for the first time, succeeded in growing three-dimensional salivary gland tissue that, when implanted into mice, produced saliva like normal glands.

11 Oct 2018

New method for studying the cell nucleus could improve disease detection

Researchers at New York University have found a way to measure the physical properties of the nucleus and its constituents in live human cells.

5 Oct 2018

Researchers insert just enough human DNA into mice to study preterm birth

Preterm birth remains a global epidemic linked to a lifetime of potential health complications. It also is difficult to study in living creatures--especially the uniquely precise biology of preterm birth in humans.

3 Oct 2018

Researchers find ALS drug as potential treatment for prostate cancer

Researchers have discovered a new use for an old drug as a potential treatment for prostate cancer. The findings are published in the journal The Prostate.

3 Oct 2018

Gene variant linked to Type 2 diabetes may predispose people to have lower body weight

A research team at the University of North Carolina at Chapel Hill's Gillings School of Global Public Health found that a well-known gene variant linked to Type 2 diabetes, called transcription Factor-7 like 2 gene, may also predispose someone to being leaner, or having a lower body weight.

3 Oct 2018

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

Researchers at the Centre for Genomic Regulation in Barcelona, Spain, have identified the mechanism by which an important enzyme involved in the differentiation of stem cells is brought to the DNA.

3 Oct 2018

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in the journal Nature Communications.

1 Oct 2018

'Kidney-gene' plays role in the central nervous system and controls movement

The WT1 gene fulfills a central role in the development of a healthy, proper functioning kidney. Mutations in WT1 lead to impairments in kidney development and cause Wilms tumors, a pediatric kidney cancer.

1 Oct 2018

Biological 'switch' influences whether immature blood cells differentiate into red or white blood cells

Japanese scientists have revealed a biological "switch" that influences whether an immature blood cell would develop into a red blood cell or a subtype of white blood cell called myeloid cells in response to infection or inflammation within the body.

26 Sep 2018

Columbia University announces winners of 2018 Louisa Gross Horwitz Prize

Columbia University has decided to award the Louisa Gross Horwitz Prize 2018.

24 Sep 2018

Scientist intends to fight pathogenic bacteria with viruses

Dr. Li Deng of Helmholtz Zentrum München has been awarded a Starting Grant of the European Research Council. The scientist intends to tackle antimicrobial resistance by fighting bacteria with their natural enemies - the viruses. The grant is endowed with nearly 1.5 million euros for five years.

21 Sep 2018

Sea squirt model reveals key molecules in dopaminergic neuron differentiation

The human brain is exceedingly complex, consisting of various regions with particular functions and approximately 100 billion neurons. This complexity has presented a major challenge in understanding this organ and how it develops, particularly in view of the ethical issues associated with research on humans.

20 Sep 2018

Researchers describe cell mechanism that optimizes proteins production in stressful situations

The different genes within the genome must be expressed in precise levels and in the exact moment if the complex balance regulating cell activity is to be maintained.

19 Sep 2018

Microbiota in the intestines and cell stress cause colon cancer

"With our study we originally wanted to study the role of bacteria in the intestines in the development of intestinal inflammation," explains Professor Dirk Haller from the Department of Nutrition and Immunology at the Weihenstephan Science Centre of the TUM.

18 Sep 2018

Scientists get unprecedented view of brain development through high-resolution genomic map

Researchers at St. Jude Children's Research Hospital have created a massive database of the changes in gene activity of individual cells in the cerebellum during embryonic development and immediately after birth.

14 Sep 2018

Discovery of key mechanism may lead to more functional skin grafts for burn victims

University of Colorado Boulder researchers have discovered a key mechanism by which skin begins to develop in embryos, shedding light on the genetic roots of birth defects like cleft palate and paving the way for development of more functional skin grafts for burn victims.

14 Sep 2018

New insight on mechanics of rotavirus could open up avenues for effective treatments

Researchers have provided new insight on the mechanics of a virus that causes severe diarrhea and sickness in young children, according to a report published in eLife.

12 Sep 2018

Researchers unravel how Zika virus manipulates the human immune system

Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that make macrophages function as immune cells.

11 Sep 2018

Transcription News and Research

Scientists reprogram mature inhibitory neurons into dopaminergic cells

Researchers develop organoid that functions as real salivary gland

Scientists succeed in growing functional salivary gland

New method for studying the cell nucleus could improve disease detection

Researchers insert just enough human DNA into mice to study preterm birth

Researchers find ALS drug as potential treatment for prostate cancer

Gene variant linked to Type 2 diabetes may predispose people to have lower body weight

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

'Kidney-gene' plays role in the central nervous system and controls movement

Biological 'switch' influences whether immature blood cells differentiate into red or white blood cells

Columbia University announces winners of 2018 Louisa Gross Horwitz Prize

Scientist intends to fight pathogenic bacteria with viruses

Sea squirt model reveals key molecules in dopaminergic neuron differentiation

Researchers describe cell mechanism that optimizes proteins production in stressful situations

Microbiota in the intestines and cell stress cause colon cancer

Scientists get unprecedented view of brain development through high-resolution genomic map

Discovery of key mechanism may lead to more functional skin grafts for burn victims

New insight on mechanics of rotavirus could open up avenues for effective treatments

Researchers unravel how Zika virus manipulates the human immune system

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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