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Researchers characterize ‘gold fingers’ using ion mobility mass spectrometry

Drugs containing gold have been used for centuries to treat conditions like rheumatoid arthritis. In addition, they might be effective against cancer and HIV.

28 Mar 2017

Study shows how antibiotics increase survival chances of bacteria

Antibiotics harm bacteria and stress them. Trimethoprim (TMP), an antibiotic, inhibits the growth of the bacterium Escherichia coli and induces a stress response.

25 Mar 2017

MSK scientists discover epigenetic mechanism promoting breast cancer

Researchers from Memorial Sloan Kettering Cancer Center (MSK) have identified, for the first time, an epigenetic mechanism promoting breast cancer.

24 Mar 2017

Chromatrap publishes new article comparing efficiency, sensitivity of native and cross-linked ChIP-seq kits

Chromatrap has published a new article that describes a detailed genome wide comparison of native and crosslinked chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) using the company's patented solid state spin column technology.

From Chromatrap® - Porvair Sciences Ltd 24 Mar 2017

SLU researchers aim to tackle diabetes and obesity by capturing benefits of exercise in pill form

With a series of new grants, Saint Louis University researchers will tackle the twin epidemics of diabetes and obesity by tapping into the potential of two nuclear receptors that control muscle metabolism.

24 Mar 2017

Heroin use linked to epigenetic alterations in the brain

Heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression, and more years of drug use correlate with higher levels of hyperacetylation, according to research conducted at The Icahn School of Medicine at Mount Sinai and published in the journal Biological Psychiatry.

22 Mar 2017

'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Consumption of the synthetic drug MDPV -a powerful psychostimulant known as 'cannibal drug'- in adolescence, can increase vulnerability of cocaine addiction during adulthood, according to a study carried out with laboratory animals and led by the researchers Elena Escubedo, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the UB and Olga Valverde, head of the Neurobiology of Behaviour Research Group of Pompeu Fabra University.

22 Mar 2017

Mettler Toledo’s Laboratory Expertise Library provides information on efficient sample preparation

In a typical analytical workflow, 49% of out-of-specification (OOS) errors can be attributed to either sample processing steps or operator error. In addition, the sample processing steps account for 61% of the manual workload.

From Mettler-Toledo International Inc. 21 Mar 2017

York researchers move closer to finding new treatments for chronic bladder diseases

Using human cells, they have mapped how different proteins bind along the DNA to control which genes are active during barrier formation.

14 Mar 2017

New method can precisely track replication of yellow fever virus in host immune cells

Researchers from Princeton University's Department of Molecular Biology have developed a new method that can precisely track the replication of yellow fever virus in individual host immune cells.

14 Mar 2017

Heroin use linked to epigenetic alterations in the brain

The past few years have seen an explosion of heroin abuse and deaths from opiate overdose. But little is known about the molecular underpinnings of heroin addiction.

14 Mar 2017

Targeting cancer stem cells may be effective way to prevent spread of squamous cell carcinoma

Targeting cancer stem cells may be a more effective way to overcome cancer resistance and prevent the spread of squamous cell carcinoma — the most common head and neck cancer and the second-most common skin cancer, according to a new study by cancer researchers at the UCLA School of Dentistry.

10 Mar 2017

Scientists pinpoint key biological mechanism that can prevent proliferation of insulin-producing cells

If you become resistant to insulin, a condition that is a precursor to type 2 diabetes, your body tries to compensate by producing more of the "beta" cells in the pancreas that produce the critical hormone.

9 Mar 2017

Penn researchers identify genome-wide changes caused by high-fat diet

By comparing two strains of mice -- one that becomes obese and diabetic on a high-fat diet and another resistant to a high-fat regimen -- researchers from the Perelman School of Medicine at the University of Pennsylvania identified genome-wide changes caused by a high-fat diet.

8 Mar 2017

Diabetes medication could be effective therapy for aggressive type of breast cancer

Researchers in China have discovered that a metabolic enzyme called AKR1B1 drives an aggressive type of breast cancer.

7 Mar 2017

Inflammation acts as double-edge sword in regeneration, study reveals

Regeneration is an inherent property of life. However, the potential to regenerate differs across species: while fish and amphibians can re-grow appendages such as limbs, tails, and fins, mammals, including humans, cannot restore injured organs to their original shape and function.

7 Mar 2017

SLU study findings suggest new method to suppress LDL cholesterol

In a paper published in Biochemical Pharmacology, Saint Louis University researchers examined the way a nuclear receptor called REV-ERB is involved in regulating cholesterol metabolism.

6 Mar 2017

HORIBA Scientific honors Dr. Ibrahim Cissé with Young Fluorescence Investigator Award

HORIBA Scientific, world leader in fluorescence spectroscopy systems, awarded Dr. Ibrahim Cissé, the class of 1922 Assistant Professor of Physics at MIT, its annual Young Fluorescence Investigator Award. HORIBA Scientific has been the sole sponsor of this award since 1997.

3 Mar 2017

Researchers develop smart genetic reference library for locating disease-causing mutations

Researchers at Hiroshima University have developed a smart genetic reference library for locating and weeding out disease-causing mutations in populations.

3 Mar 2017

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

A Japanese research group has discovered that a newly-identified autoimmune endocrine disease that leads to hypopituitarism is caused by thymomas (a type of tumor originating from the thymic gland).

2 Mar 2017

Transcription News and Research

Researchers characterize ‘gold fingers’ using ion mobility mass spectrometry

Study shows how antibiotics increase survival chances of bacteria

MSK scientists discover epigenetic mechanism promoting breast cancer

Chromatrap publishes new article comparing efficiency, sensitivity of native and cross-linked ChIP-seq kits

SLU researchers aim to tackle diabetes and obesity by capturing benefits of exercise in pill form

Heroin use linked to epigenetic alterations in the brain

'Cannibal drug' consumption in adolescence can increase vulnerability to cocaine use during adulthood

Mettler Toledo’s Laboratory Expertise Library provides information on efficient sample preparation

York researchers move closer to finding new treatments for chronic bladder diseases

New method can precisely track replication of yellow fever virus in host immune cells

Heroin use linked to epigenetic alterations in the brain

Targeting cancer stem cells may be effective way to prevent spread of squamous cell carcinoma

Scientists pinpoint key biological mechanism that can prevent proliferation of insulin-producing cells

Penn researchers identify genome-wide changes caused by high-fat diet

Diabetes medication could be effective therapy for aggressive type of breast cancer

Inflammation acts as double-edge sword in regeneration, study reveals

SLU study findings suggest new method to suppress LDL cholesterol

HORIBA Scientific honors Dr. Ibrahim Cissé with Young Fluorescence Investigator Award

Researchers develop smart genetic reference library for locating disease-causing mutations

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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