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Accelrys releases Pipeline Pilot NGS Collection at Molecular Medicine Tri-Conference

Accelrys, Inc. (NASDAQ:ACCL), the leading scientific informatics software and services company, today announced at the Molecular Medicine Tri-Conference its entrance in the rapidly growing next generation sequencing (NGS) market with the release of the NGS Collection for Pipeline Pilot.

24 Feb 2011

Orthopaedic groups select Entrada's automated clinical documentation solution

Two large orthopaedic groups have become the most recent customers of Entrada, a company changing the way physicians document patient encounters and use electronic health records (EHRs).

23 Feb 2011

Knocking out genes completely and exclusively in Natural Killer cells

Our immune systems contain three fundamentally different types of cell: B-cells, T-cells and the mysteriously named Natural Killer cells (NK cells), which are known to be involved in killing tumour cells and other infected cells. Experiments to investigate the function of NK cells have proven difficult to interpret because the interactions between the various components of the immune system make it almost impossible to isolate effects of individual cell types.

23 Feb 2011

Loss of 'twenty-four' gene makes it harder to wake up

Northwestern University scientists have discovered a new mechanism in the core gears of the circadian clock. They found the loss of a certain gene, dubbed "twenty-four," messes up the rhythm of the common fruit fly's sleep-wake cycle, making it harder for the flies to awaken.

17 Feb 2011

Study sheds light on novel functions of certain PCSK enzymes

Recent studies conducted at the Institut de recherches cliniques de Montr-al on a group of PCSK enzymes could have a positive impact on health, from cholesterol to osteoporosis.

17 Feb 2011

Study sheds new light on riboswitch that turns genes on or off in response to cell's energy needs

Scientists from The Scripps Research Institute have shed new light on a molecular switch that turns genes on or off in response to a cell's energy needs.

13 Feb 2011

Transcend fourth quarter revenue increases 26% to $26,976,000

TRANSCEND SERVICES, INC., a leading provider of clinical documentation solutions to the U.S. healthcare market, today announced its unaudited financial results for the fourth quarter and year ended December 31, 2010.

3 Feb 2011

Agilent introduces first commercial RNA target enrichment system

Agilent Technologies, Inc., today introduced SureSelect RNA Capture Kits, the first commercial RNA target enrichment system enabling geneticists to focus on specific genomic loci or transcripts of research interest. The RNA capture kits make it possible to precisely measure expression levels of genes of interest and detect allelic-specific expression, splicing events and gene fusions.

3 Feb 2011

Five young scientists receive Damon Runyon-Rachleff Innovation Award for cancer research

The Damon Runyon Cancer Research Foundation announced that five scientists with novel approaches to fighting cancer have been named 2011 recipients of the Damon Runyon-Rachleff Innovation Award. The grant of $450,000 over three years is awarded each year to early career scientists whose projects have the potential to significantly impact the prevention, diagnosis and treatment of cancer.

2 Feb 2011

First commercially available full length human MTOR protein with superior biological activity released

OriGene Technologies, Inc., a gene-centric life sciences company, releases the first commercially available full length human MTOR protein with superior biological activity.

2 Feb 2011

Study finds E2F5 transcription factor commonly overexpressed in primary human HCC

E2F5 is a member of the E2F transcription factor family, and plays a key role in cell growth and proliferation. Overexpression of E2F5 has been reported in various human cancers, but not in liver cancer, and its biological implication is largely unknown. It is not known whether E2F5 plays a tumor suppressor role or an oncogenic role.

1 Feb 2011

Research provides new clues for compulsive behavior, cognitive defects linked with LND

Research from the University of California, San Diego School of Medicine provides new clues for the compulsive behavior and cognitive defects associated with a rare childhood neurological disease called Lesch-Nyhan Disease.

29 Jan 2011

Acetylation complex fits like a halo over a histone

To understand the emerging science of epigenetics-a field that describes how genes may be regulated without altering the underlying DNA itself-scientists are deciphering the many ways in which enzymes act on the proteins surrounding DNA within cells.

21 Jan 2011

Researchers take systematic approach to catalog factors that control blood cell development

A small pool of stem cells replenishes the human body with about 200 billion new blood cells daily. But the elaborate circuitry that determines if a cell will develop into a T cell, red blood cell, or one of the nine or more other blood cell types remains largely unknown. A research team led by scientists from the Broad Institute and Brigham and Women's Hospital has taken a systematic approach to help decipher this circuitry, compiling a comprehensive catalog of the factors that determine a blood cell's fate.

21 Jan 2011

Three ASM scientists to receive NAS award for excellence in microbiology field

Three members of the American Society for Microbiology are among the 13 scientists that will be honored by the National Academy of Sciences with awards recognizing extraordinary scientific achievement in the field of microbiology:

21 Jan 2011

Scientists discover fundamental mechanism behind toxic protein aggregation in neurodegenerative diseases

Protein aggregation underlies several neurodegenerative diseases such as Alzheimer's, Huntington's chorea or Parkinson's. Scientists at the Max Planck Institute of Biochemistry (MPIB) in Martinsried near Munich, Germany, now discovered a fundamental mechanism which explains how toxic protein aggregation occurs and why it leads to a widespread impairment of essential cellular functions.

20 Jan 2011

MGH researchers discover massive overexpression of DNA sequences in cancer cells

Massachusetts General Hospital Cancer Center researchers have discovered a previously unknown feature of common tumor cells - massive overexpression of certain DNA sequences that do not code for proteins.

14 Jan 2011

All fat cells not the same

All fat cells are not the same - a fact that has implications in the understanding and treatment of type 2 diabetes and obesity, said researchers from Baylor College of Medicine (www.bcm.edu) in a report that appears in the current issue of the Journal of Cell Biology (http://www.jcb.rupress.org/).

10 Jan 2011

Enzon to commence EZN-4176 Phase 1a/1b study in castration-resistant prostate cancer

Enzon Pharmaceuticals, Inc. today announced the Investigational New Drug (IND) approval by the US Food and Drug Administration (FDA) and plan to commence enrollment into a Phase 1a/1b study shortly. The study will evaluate the safety and tolerability of EZN-4176, the company's novel androgen receptor (AR) mRNA antagonist, for the treatment of patients with castration-resistant prostate cancer (CRPC).

10 Jan 2011

Isis Pharmaceuticals announces addition of two new drugs to development pipeline

Isis Pharmaceuticals, announced today that it has added two new drugs to its development pipeline, ISIS-FGFR4Rx and ISIS-STAT3Rx.

7 Jan 2011

Transcription News and Research

Accelrys releases Pipeline Pilot NGS Collection at Molecular Medicine Tri-Conference

Orthopaedic groups select Entrada's automated clinical documentation solution

Knocking out genes completely and exclusively in Natural Killer cells

Loss of 'twenty-four' gene makes it harder to wake up

Study sheds light on novel functions of certain PCSK enzymes

Study sheds new light on riboswitch that turns genes on or off in response to cell's energy needs

Transcend fourth quarter revenue increases 26% to $26,976,000

Agilent introduces first commercial RNA target enrichment system

Five young scientists receive Damon Runyon-Rachleff Innovation Award for cancer research

First commercially available full length human MTOR protein with superior biological activity released

Study finds E2F5 transcription factor commonly overexpressed in primary human HCC

Research provides new clues for compulsive behavior, cognitive defects linked with LND

Acetylation complex fits like a halo over a histone

Researchers take systematic approach to catalog factors that control blood cell development

Three ASM scientists to receive NAS award for excellence in microbiology field

Scientists discover fundamental mechanism behind toxic protein aggregation in neurodegenerative diseases

MGH researchers discover massive overexpression of DNA sequences in cancer cells

All fat cells not the same

Enzon to commence EZN-4176 Phase 1a/1b study in castration-resistant prostate cancer

Isis Pharmaceuticals announces addition of two new drugs to development pipeline

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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