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Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study demonstrates that inhibiting stromal class I histone deacetylases (HDACs) can effectively slow down pancreatic cancer progression, shedding light on a new therapeutic approach targeting the tumor microenvironment.

10 Dec 2023

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

It only takes holding your breath for slightly too long to understand that too little oxygen is bad for you. But can you also have too much? Indeed, breathing air with a higher oxygen level than your body needs can cause health problems or even death.

8 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

Researchers created Drosophila models using multi-omics profiles to elucidate the biological mechanisms and effects of everyday low-intensity blue light exposure (BLE).

7 Dec 2023

New genetic links to coronary artery calcification uncovered, offering treatment insights

A study in Nature Cardiovascular Research identifies two new genetic loci associated with coronary artery calcification (CAC), a key indicator of atherosclerosis and coronary artery disease.

5 Dec 2023

Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer

Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms.

5 Dec 2023

Osteopontin-c: A key player in mitochondrial biogenesis and cancer metastasis

A new research paper was published in Oncotarget's Volume 14 on December 1, 2023, entitled, "Osteopontin induces mitochondrial biogenesis in deadherent cancer cells."

5 Dec 2023

Study reveals how maternal diabetes affects birth defects at the single-cell level

The mechanisms by which maternal diabetes mellitus contributes to congenital abnormalities in the fetus.

4 Dec 2023

Gut microbe Lactobacillus found to bolster stress resilience, new study reveals

Study demonstrates that the gut microbe Lactobacillus helps maintain normal levels of the cytokine interferon-gamma (IFNγ), providing protection against stress-induced disruptions in a mouse model. The findings suggest Lactobacillus's crucial role in building resilience to environmental stressors, highlighting its potential in treating mood disorders.

3 Dec 2023

New study provides convincing evidence of the essential role of cylicins in sperm development and fertility

Researchers investigated the Role of Cylicins in Spermiogenesis and Male Fertility in Mice and Humans through Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/ CRISPR-associated protein 9 (Cas9) Gene Editing.

30 Nov 2023

The effects of vitamin K on bone health

Existing scientific data on the effects of vitamin K (VK) on bone health and elucidated the underlying mechanisms.

30 Nov 2023

Portable AI-driven COVID-19 test detects variants with high accuracy

A new AI-assisted molecular diagnostic platform capable of identifying variants of COVID-19 and other infectious diseases has been developed by scientists in the UK. The low cost, portable device could play a crucial role in preventing future pandemics due to its accuracy and versatility.

29 Nov 2023

Decoding anxiety: Study reveals brain's role in behavioral inhibition risks

Researchers in the U.S. used non-human primate models to explore the molecular mechanisms and neural systems behind behavioral inhibition, a key risk factor for anxiety disorders. The study identified molecular systems in the posterior orbitofrontal cortex linked to variations in anxious temperament, offering potential targets for treating anxiety disorders.

28 Nov 2023

New heart organoid model could revolutionize drug development and toxicology studies

Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists – so far.

28 Nov 2023

Scientists uncover new therapeutic targets for high-risk pediatric leukemia

Scientists at St. Jude Children's Research Hospital comprehensively identified genes directly regulated by a protein associated with high-risk pediatric leukemias.

28 Nov 2023

Potential breakthrough in breast cancer: Five proteins identified as risk markers

Researchers used a Mendelian randomization approach to conduct a genetic association analysis of the levels of over 3,000 proteins to identify biomarkers for early breast cancer detection.

28 Nov 2023

Omega-3s in the spotlight: The impact of EPA and DHA on athlete health and performance

Research paper reviews the effects of omega-3 fatty acids, EPA, and DHA, on athletes, discussing their benefits in inflammation control, cognitive function, and muscle maintenance, and the need for further research to fully understand their impact. It also addresses the risks and optimal intake of these supplements, highlighting their potential to improve athletic performance and recovery with minimal adverse effects at recommended doses.

27 Nov 2023

Transcription News and Research

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

New genetic links to coronary artery calcification uncovered, offering treatment insights

Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer

Osteopontin-c: A key player in mitochondrial biogenesis and cancer metastasis

Study reveals how maternal diabetes affects birth defects at the single-cell level

Gut microbe Lactobacillus found to bolster stress resilience, new study reveals

New study provides convincing evidence of the essential role of cylicins in sperm development and fertility

The effects of vitamin K on bone health

Portable AI-driven COVID-19 test detects variants with high accuracy

Decoding anxiety: Study reveals brain's role in behavioral inhibition risks

New heart organoid model could revolutionize drug development and toxicology studies

Scientists uncover new therapeutic targets for high-risk pediatric leukemia

Potential breakthrough in breast cancer: Five proteins identified as risk markers

Omega-3s in the spotlight: The impact of EPA and DHA on athlete health and performance

Genetic vulnerability of leukemia cells uncovered

Scientists uncover key to enhancing cancer-killing T cells

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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