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$153,000 grant fuels research on new approaches to inhibit STAT3 and develop novel cancer treatments

With an estimated 1.9 million new cases and more than 600,000 deaths each year, cancer remains the second most common cause of death in the U.S., trailing only heart disease. And while there are more than 200 types of cancer, the abnormal synthesis of a protein known as STAT3 is unique to the majority of tumors.

13 Dec 2023

New organoid model could revolutionize neuroendocrine tumor research

The Organoid Group (Hubrecht Institute) and the Rare Cancers Genomics Team (IARC/WHO) found a way to grow samples of different types of neuroendocrine tumors (NETs) in the lab.

11 Dec 2023

New report provides latest update on cardiovascular disease burden and trends

A world without cardiovascular disease (CVD) is possible, yet millions of lives are lost prematurely to heart disease each year, according to the new Global Burden of Disease (GBD) special report published today in the Journal of the American College of Cardiology.

11 Dec 2023

Groundbreaking online community connects Progeria patients worldwide

A ground-breaking online community has been launched to allow people with the rare disease Progeria to communicate regardless of their location or language.

11 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

EULAR publishes updated recommendations for SLE management

SLE is a heterogeneous disease, which can cause many different manifestations and symptoms, and traditionally did not have many treatment options.

8 Dec 2023

New guidelines offer hope for fatigue management in people with inflammatory RMD

Fatigue is common in people with inflammatory rheumatic and musculoskeletal diseases(RMD). The causes of fatigue are not well understood, and it is likely that they vary between people and over time.

8 Dec 2023

Study offers new hope for heart repair and regeneration with reduced mitochondrial activity

USF Health Heart Institute doctors are upbeat about cardiac regeneration. But when those batteries – heart muscle cells called cardiomyocytes − short circuit and die, the damage can be devastating.

8 Dec 2023

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target delivery to other tissues.

8 Dec 2023

Researchers identify 25 new genetic markers linked to peptic ulcers

Researchers studied stomach and duodenal ulcers in a large research project comparing Japanese and European populations.

7 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

New consensus report highlights progress and potential of precision medicine in diabetes

A new international consensus report on precision medicine in diabetes prevention and care highlights the significant advancements in precision medicine in diabetes prevention, diagnosis, treatment, and prognosis while also shedding light on numerous knowledge gaps.

5 Dec 2023

Deep learning models can improve low-field MRI images for better clinical diagnoses

Image-to-image translation model LoHiResGAN.

5 Dec 2023

New discovery unveils an additional layer of the CRISPR-Cas antiviral defense system

The recent publication in Science by Mogila, Tamulaitiene et al. represents a continuation of the successful scientific research conducted by Gintautas Tamulaitis' group.

4 Dec 2023

MAbID offers a deep dive into chromatin dynamics and gene regulation

Researchers from the group of Jop Kind developed a new technique called MAbID. This allows them to simultaneously study different mechanisms of gene regulation, which plays a major role in development and disease.

4 Dec 2023

UK Biobank unveils world's largest genetic data set

In a momentous landmark for medical research, UK Biobank has today [Thursday 30 November] unveiled incredible new data from whole genome sequencing of its half a million participants.

4 Dec 2023

Nanotechnology could enhance traditional Chinese medicine delivery, promising improved clinical outcomes

This review in the Journal of Nanobiotechnology explores how nanotechnology enhances the delivery of traditional Chinese medicines (TCMs), overcoming challenges like poor solubility and limited bioavailability. Nanocarriers like liposomes and nanoparticles improve TCM delivery, offering greater therapeutic effectiveness and reduced side effects, but face challenges in biocompatibility and stability for clinical use.

30 Nov 2023

Translation News and Research

$153,000 grant fuels research on new approaches to inhibit STAT3 and develop novel cancer treatments

New organoid model could revolutionize neuroendocrine tumor research

New report provides latest update on cardiovascular disease burden and trends

Groundbreaking online community connects Progeria patients worldwide

Study explores the intricate gut-brain-liver connection and its impact on health

EULAR publishes updated recommendations for SLE management

New guidelines offer hope for fatigue management in people with inflammatory RMD

Study offers new hope for heart repair and regeneration with reduced mitochondrial activity

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

Researchers identify 25 new genetic markers linked to peptic ulcers

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

New consensus report highlights progress and potential of precision medicine in diabetes

Deep learning models can improve low-field MRI images for better clinical diagnoses

New discovery unveils an additional layer of the CRISPR-Cas antiviral defense system

MAbID offers a deep dive into chromatin dynamics and gene regulation

UK Biobank unveils world's largest genetic data set

Nanotechnology could enhance traditional Chinese medicine delivery, promising improved clinical outcomes

UK Biobank data opens door to new era of precision medicine

Researchers investigate the advantages and disadvantages of two types of contraceptive coils

A new research agenda on health, migration, and displacement by the World Health Organization

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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