Transplant News and Research

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Cell therapy slows progression of metachromatic leukodystrophy

In an important discovery, scientists have demonstrated that the progression of a type of genetic brain disease is slowed and symptoms are improved in mice that received cell transplants.

23 Mar 2006

Stem cells, gene therapy and allograft applications show promise for treating orthopaedic conditions

Recent advances in gene therapy, stem cells and other promising applications are offering new hope for patients and helping orthopaedic surgeons provide state-of-the-art treatment for various frame-related conditions.

23 Mar 2006

University of Calgary researchers develop bioreactor procedures to grow pancreatic cells in their laboratory

Freedom from insulin injections and the myriad of health problems related to type 1 diabetes is closer to becoming reality, thanks to University of Calgary researchers who are developing the first bioreactor procedures to grow pancreatic cells in their laboratory.

21 Mar 2006

Rapamycin (sirolimus) may be effective in treating kidney disease

A widely available drug may be effective in treating kidney disease, report scientists at the University of California, Santa Barbara. They describe the discovery in the online edition of the Proceedings of the National Academies of Science.

21 Mar 2006

Human papillomavirus may be a risk factor in developing squamous cell carcinoma

The study, published in the March 15 issue of the Journal of the National Cancer Institute, used new technology to detect antibodies from a strain of HPV on skin cancer samples.

20 Mar 2006

New model is able to accurately predict survival for patients with heart failure

A new model developed at the University of Washington provides an accurate estimate of one-, two-, and three-year survival rates and average years of survival for patients with heart failure.

15 Mar 2006

Researchers find viable new sources for stem cell transplants to the heart

Stem cell transplantation is among one of the most exciting and hotly debated areas of medical research today. While the promise of personalized medicine and effective treatments for debilitating diseases drive progress in this area, moral and ethical dilemmas about embryonic cells continues to cloud the field.

14 Mar 2006

Decitabine improves patient outcomes in myelodysplastic syndromes

Decitabine, a new drug undergoing Phase III efficacy trials, provides palliative therapy for patients with the bone marrow disease called Myelodysplastic Syndrome (MDS), according to a new study.

14 Mar 2006

Exposure to toxins from hazardous waste sites may be a significant risk factor for developing primary biliary cirrhosis

Published in the March 2006 issue of Hepatology, researchers found significant clusters of the disease near Superfund toxic waste sites (SFS) and that the majority of patients in New York City who need liver transplants because of PBC, reside near SFS.

13 Mar 2006

Transplanting a pair of kidneys with limited function into one patient may offer one solution to short supply of donated kidneys

Transplanting a pair of kidneys with limited function into one patient can be just as successful as the standard procedure in which a patient receives a single kidney, according to new research at Wake Forest University Baptist Medical Center.

13 Mar 2006

Scientists fight leukaemia with 'natural killer' cells

Scientists at the University of the West of England and the Bone Marrow Transplant Unit at the Bristol Children's Hospital have just won funding for a two-year project aimed at improving the outcome of bone marrow stem-cell transplants in young leukaemia patients.

8 Mar 2006

Validation of cardiovascular risk scores in a liver transplant population

Two methods of assessing a patient's risk of cardiovascular events - SCORE and PROCAM - proved more valuable for liver transplant recipients than an alternative method, according to a new study.

7 Mar 2006

Extensive study of natalizumab

Scientists have completed an extensive study of more than 3,000 patients who received a promising anti-inflammatory drug, natalizumab, that was linked to three cases of a serious brain infection in large clinical trials halted in early 2005.

7 Mar 2006

Plastic surgeons describe possibility of full facial tissue transplantation from one human body to another

Even after news of the first partial facial transplantation performed in France spread around the world, plastic surgeons have continued to research how to make the first full facial transplantation a reality.

7 Mar 2006

Researchers transplant insulin-producing neonatal porcine islet cells into monkeys

A team of researchers from the University of Alberta, the Yerkes National Primate Research Center of Emory University and the Emory Transplant Center has successfully transplanted insulin-producing neonatal porcine islet cells into monkeys, a procedure the researchers say represents a promising intermediate solution to the critical supply problem in clinical islet cell transplantation.

27 Feb 2006

Reovirus may be able to eliminate cancer cells from autologous stem cell transplants

Medical studies show that a common virus may be able to eliminate cancer cells from autologous stem cell transplants.

21 Feb 2006

Pfizer receives FDA approval for Eraxis to treat candidemia

Pfizer said today that Eraxis (anidulafungin) has been approved by the U.S. Food and Drug Administration to treat candidemia, a potentially life-threatening bloodstream infection. Candidemia is the most deadly of the common hospital-acquired bloodstream infections, with a mortality rate of approximately 40 percent.

21 Feb 2006

Pig cells reverse diabetes in monkeys

A team of researchers in the U.S. have successfully reversed diabetes in monkeys using transplanted islet cells from pigs.

21 Feb 2006

Breakthrough anti-inflammatory treatment

Scientists from the Garvan Institute of Medical Research have developed what could be the next big blockbuster treatment for inflammatory diseases such as rheumatoid arthritis and asthma.

21 Feb 2006

New device to boost supply and quality of blood platelets

Cancer and open-heart surgery patients, disaster victims, organ or bone marrow transplant recipients, and others who require life-saving blood platelet transfusions will benefit from equipment invented by a researcher at the University of British Columbia's Centre for Blood Research (CBR).

21 Feb 2006

Transplant News and Research

Cell therapy slows progression of metachromatic leukodystrophy

Stem cells, gene therapy and allograft applications show promise for treating orthopaedic conditions

University of Calgary researchers develop bioreactor procedures to grow pancreatic cells in their laboratory

Rapamycin (sirolimus) may be effective in treating kidney disease

Human papillomavirus may be a risk factor in developing squamous cell carcinoma

New model is able to accurately predict survival for patients with heart failure

Researchers find viable new sources for stem cell transplants to the heart

Decitabine improves patient outcomes in myelodysplastic syndromes

Exposure to toxins from hazardous waste sites may be a significant risk factor for developing primary biliary cirrhosis

Transplanting a pair of kidneys with limited function into one patient may offer one solution to short supply of donated kidneys

Scientists fight leukaemia with 'natural killer' cells

Validation of cardiovascular risk scores in a liver transplant population

Extensive study of natalizumab

Plastic surgeons describe possibility of full facial tissue transplantation from one human body to another

Researchers transplant insulin-producing neonatal porcine islet cells into monkeys

Reovirus may be able to eliminate cancer cells from autologous stem cell transplants

Pfizer receives FDA approval for Eraxis to treat candidemia

Pig cells reverse diabetes in monkeys

Breakthrough anti-inflammatory treatment

New device to boost supply and quality of blood platelets

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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