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Red meat and colon cancer recurrence

Colon cancer patients who eat a diet high in red meat, fatty products, refined grains, and desserts a so-called Western diet may be increasing their chance of disease relapse and early death, report researchers at Dana-Farber Cancer Institute.

16 Aug 2007

Cytokines shown to be a cause of type 2 diabetes

In the first large scale, multiethnic study of its kind, researchers at UCLA have confirmed the role played by three particular molecules known as cytokines as a cause of Type 2 diabetes, and further, have identified these molecules as early biological markers that may be used to more accurately predict future incidences of diabetes among apparently healthy individuals.

16 Aug 2007

Metformin kills some cancer cells

Researchers at the University of Pennsylvania School of Medicine have found that a commonly prescribed diabetes drug kills tumor cells that lack a key regulatory gene called p53.

16 Aug 2007

Discovery of new mechanism of resistance to endocrine or anti-hormonal therapies

When a woman receives a breast cancer diagnosis her entire life may change in the blink of an eye.

13 Aug 2007

New drug targets for multiple myeloma

Research investigators have identified molecular changes in multiple myeloma cells that activate an important biological pathway associated with cell growth and survival, thereby revealing potential new targets for drugs to treat this cancer.

13 Aug 2007

New cancer stem cells could aid breast cancer research

In some ways, certain tumors resemble bee colonies, says pathologist Tan Ince. Each cancer cell in the tumor plays a specific role, and just a fraction of the cells serve as "queens," possessing the unique ability to maintain themselves in an unspecialized state and seed new tumors. These cells can also divide and produce the "worker" cells that form the bulk of the tumor.

13 Aug 2007

Alarm over death in clinical trial for arthritis therapy

The death of a woman taking part in a clinical trial for an arthritis therapy has set alarm bells ringing in the United States.

12 Aug 2007

Light-activated molecules used to induce apoptosis in cancer cells

A key challenge facing doctors as they treat patients suffering from cancer or other diseases resulting from genetic mutations is that the drugs at their disposal often don't discriminate between healthy cells and dangerous ones -- think of the brute-force approach of chemotherapy, for instance.

12 Aug 2007

New pathway for inflammation-induced cancer

A well-known inflammatory protein spawns an enzyme that inactivates two tumor-suppressing genes, ultimately triggering production of new blood vessels to nourish breast cancer cells, researchers at The University of Texas M. D. Anderson Cancer Center report in the August edition of the journal Cell .

11 Aug 2007

Promising new line in anti-cancer therapy

A promising new line in anti-cancer therapy by blocking the molecular motors involved in copying genetic information during cell division is being pursued by young Dutch researcher Dr. Nynke Dekker in one of this year's EURYI award winning projects sponsored by the European Science Foundation (ESF) and the European Heads of Research Councils (EuroHORCS).

11 Aug 2007

Scientists find mechanisms controlling metastasis of breast cancer cells

When cancer cells dissociate from the original tumor and migrate via the blood stream to colonize distant organs, is the main cause of cancer death.

9 Aug 2007

New test to detect early stage liver cancer

Cancer of the liver is very difficult to detect, and it is a major cause of death in Asia and Africa, with rising incidence in Western countries as well.

9 Aug 2007

Increased cure of breast cancer with extra boost irradiation after surgery

A large European study shows that an extra "boost dose" of irradiation after surgery for breast cancer improves the chance of cure.

8 Aug 2007

High-intensity focused ultrasound may alerts the immune system to cancer

An intense form of ultrasound that shakes a tumor until its cells start to leak can trigger an alarm that enlists immune defenses against the cancerous invasion, according to a study led by researchers at Duke University's Pratt School of Engineering.

8 Aug 2007

Diets high in the nutrient choline may increase risk for colorectal polyps

Contrary to expectations, diets high in the nutrient choline were associated with an increased risk of some colorectal polyps, which can, but do not always, lead to colorectal cancer, according to a study published online in the August 7 Journal of the National Cancer Institute.

8 Aug 2007

Mechanistic model of DNA repair

Ionizing radiation, toxic chemicals, and other agents continually damage the body's DNA, threatening life and health: unrepaired DNA can lead to mutations, which in turn can lead to diseases like cancer.

6 Aug 2007

LKB1 gene - new lung tumor-suppressor

Collaborating scientists in Boston and North Carolina have found that a particular gene can block key steps of the lung cancer process in mice.

6 Aug 2007

Biologists discover one reason why chromosomes break, often leading to cancer

In the past ten years, researchers in genome stability have observed that many kinds of cancer are associated with areas where human chromosomes break.

6 Aug 2007

Electricity - a new weapon for stalling the progression of cancer

Low-intensity electric fields can disrupt the division of cancer cells and slow the growth of brain tumors, suggest laboratory experiments and a small human trial, raising hopes that electric fields will become a new weapon for stalling the progression of cancer.

3 Aug 2007

Jump in cancer-related clots

Blood clots are increasingly common in cancer patients, but University of Rochester Medical Center researchers have created a novel risk model that can predict, with 98 percent certainty, which patients will not get a blood clot.

3 Aug 2007