Tumor Necrosis Factor News and Research

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Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Researchers performed a multi-omics evaluation of HSPCs obtained from individuals with myeloproliferative neoplasms transforming to TP53-related secondary forms of acute myeloid leukemia.

7 Sep 2023

Eating for health: how dietary interventions impact pre-diabetic oral and gut microbiome, metabolites and cytokines

Researchers evaluated the impact of two diets on the intestinal and oral microbiota, cytokines, and metabolites of 200 pre-diabetic individuals.

7 Sep 2023

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Researchers at Washington University have demonstrated that early life exposure to multiple viruses in house mice dampens the immune response to SARS-CoV-2 vaccinations later in life. The study raises concerns about the applicability of common mouse models in immunological research, suggesting that prior pathogen exposure could be a significant variable in predicting vaccine efficacy.

5 Sep 2023

Could medicinal plants be the key to reversing cognitive decline?

Researchers explore available evidence that medicinal plants may help improve cognitive function by reducing brain inflammation.

5 Sep 2023

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Researchers explore the potential utility of ginger essential oil in preventing NASH.

29 Aug 2023

Inflammatory diets raise dementia and Alzheimer's risk

This research study links higher Dietary Inflammatory Index (DII) scores to an increased risk of developing dementia, specifically Alzheimer's disease. The findings suggest that anti-inflammatory diets may offer a preventive strategy for dementia, underlining the need for further research to validate these associations.

28 Aug 2023

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases.

28 Aug 2023

How have inflammatory bowel disease treatments changed after the introduction of biologics?

Researchers compared changes in inflammatory bowel disease treatment strategies before and after the introduction of biologics in Japan.

24 Aug 2023

CPAP therapy can mitigate telomere shortening in sleep apnea patients

Obstructive sleep apnea (OSA) consists of multiple episodes of partial or complete closure of the upper airway that occur during sleep, leading to breathing cessation lasting more than ten seconds and sometimes even several minutes, followed by arousals and deep breathing.

23 Aug 2023

COVID-19 associated with increased risk of developing various autoimmune diseases and risk could be attenuated by vaccination

COVID-19 can increase the risk of various autoimmune diseases; however, this risk appears to be mitigated by vaccination against COVID-19.

21 Aug 2023

Study finds inverse correlation between dietary magnesium intake and peripheral arterial disease

Researchers conducted a cross-sectional study to investigate the association between dietary magnesium intake and peripheral arterial disease (PAD).

16 Aug 2023

The interplay between immunity, the nervous system, and microbiota

Researchers review the influence of the gut microbiota on neural and immune network

15 Aug 2023

Can nutritional interventions positively impact psoriasis severity?

Improvement in psoriasis (Ps) through nutritional strategies.

15 Aug 2023

How does sun exposure affect skin microbiota composition and diversity?

Researchers recruited healthy volunteers to study how ultraviolet radiation exposure impacted their skin microbiota composition, diversity, and overall skin health.

10 Aug 2023

How conversion between different types of cell death contributes to disease

Researchers elucidate the role of cell death in the pathogenesis of different diseases.

10 Aug 2023

The green tea effect: From gut microbes to weight loss, new insights emerge

The impact of green tea and its functional components on body weight and gut microbiota regulation.

8 Aug 2023

Managing inflammatory bowel disease during pregnancy

Researchers presented information on scientific evidence-based inflammatory bowel disease management methods during pregnancy.

7 Aug 2023

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

7 Aug 2023

Study reports the first protein-based diagnostic signature to discriminate MIS-C from Kawasaki Disease and other common infections

Researchers explore the distinguishing features of MIS-C as compared to other inflammatory-infectious syndromes in children.

4 Aug 2023

Can vitamin D have positive effects on reducing cortical pathology, oxidative stress, and neurofilament light chain serum levels?

Researchers use an established murine model of cortical inflammatory demyelination to investigate the effects of vitamin D.

2 Aug 2023