Tumorigenesis News and Research

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Tumorigenesis is the process involved in the production of a new tumor or tumors.

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

11 May 2023

Research sheds light on the early cellular events that give rise to pancreatic cancer

Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins.

11 May 2023

Game-changers reshaping our world: From mRNA vaccines to AI-powered medicine

The paper covers recent breakthroughs in science and technology that can bring immediate and long-term changes to human life while prioritizing sustainability.

8 May 2023

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

New study aims to elucidate the role of p21 in chronic lung inflammation

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 7, entitled, "p21 facilitates chronic lung inflammation via epithelial and endothelial cells."

18 Apr 2023

Study uncovers hallmarks to improving pancreatic cancer therapy

Scientists from the University of California, Irvine, the University of Michigan and the University of Texas MD Anderson Cancer Center have made a significant contribution to the field of pancreatic cancer research.

13 Apr 2023

Interplay between Western diet, gut microbiota, and cancer development

In a review article published in the journal Seminars in Immunology, scientists have explored the relationship between the Western diet, gut microbiota, and cancer development.

4 Apr 2023

ADHD symptoms linked to early childhood exposure to polyfluoroalkyl substances

A study explores the association of PFAS exposure with ADHD symptoms.

28 Mar 2023

Why are colon cancer rates in young people rising?

In a recent perspective article published in the journal Science, researchers at the Young-Onset Colorectal Cancer Center of Dana-Farber Cancer Institute emphasized that a better understanding of the etiology of early-onset colorectal cancer (EOCRC) is crucial to managing its increasing incidence worldwide

21 Mar 2023

Embryonic stem cells used to recreate thyroid cancer histotypes

A recent Nature Communications study revealed the recapitulating capacity of human embryonic stem cells (hESCs) to elucidate the cellular hierarchy of the thyroid gland. Furthermore, these cells possessed the capacity to reproduce the oncogenic process using the CRISPR-based genetic editing method.

14 Mar 2023

Scientists discover how a "poisoned" form of protein could spur cancer formation

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers.

17 Feb 2023

Pathological significance of CEACAMS 1, 5, and 6 in cancer biology, immunology and inflammatory disease

A new review was published in Genes & Cancer on February 1, 2023, entitled, "CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens."

10 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

Research reveals the cellular origin of cancer-associated fibroblasts

A type of cell that plays a key role in pancreatic cancer can trace its origin back to a structure that forms during embryonic development, new research at MUSC Hollings Cancer Center shows.

20 Jan 2023

Bacteria play specific roles in cancer

In a recent article published in the journal Immunity, the authors discussed the findings from a 2022 study by Galeano Niño et al., which reported that microbiota associated with tumors form micro-niches and play a role in epithelial and immune mediations of cancer.

12 Jan 2023

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

A new research paper was published in Oncotarget's Volume 13 on December 20, 2022, entitled, "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression."

6 Jan 2023

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

Lung cancer is the leading cause of death in Japan and across the globe. Among all the cancers, lung cancer has one of the lowest five-year survival rates.

28 Dec 2022

Activated vitamin D3 inhibits arsenic-mediated carcinogenesis in certain skin cells, research shows

According to recent estimates, over 140 million people from 50 countries regularly get exposed to arsenic through drinking water.

16 Dec 2022

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

HKUMed researchers at AIDS Institute, Department of Microbiology and Department of Surgery, School of Clinical Medicine, and School of Biomedical Sciences discover the role of an isoformic programmed cell death protein 1 (PD-1), namely Δ42PD-1, in suppressing the function of killer T cells, which is a type of immune cells essential for killing cancer cells among hepatocellular carcinoma (HCC) patients.

15 Dec 2022

Overexpression of lncRNA MVIH may serve as a potential diagnostic biomarker in cervical cancer

A new research paper was published in Genes & Cancer on November 23, 2022, entitled, "Ectopic expression of lncRNA MVIH as a potential diagnostic biomarker in cervical cancer."

9 Dec 2022