Typhoid News and Research

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U.N. official says humanitarian situation in Syria deteriorating but efforts to reach those affected continue

"Humanitarian agencies are trying to keep up with the rising needs stemming from the ongoing conflict in Syria, the top United Nations relief official said Tuesday, while noting that limited access is preventing everyone who requires assistance from receiving it," the U.N. News Centre reports.

21 Feb 2013

Study finds specific way in which Salmonella counteract defense mechanisms of human cells

A new study by researchers at Imperial College London has identified a way in which Salmonella bacteria, which cause gastroenteritis and typhoid fever, counteract the defence mechanisms of human cells.

16 Nov 2012

CUMC researchers develop first true mouse model of typhoid infection

Columbia University Medical Center (CUMC) researchers have created the first true mouse model of typhoid infection. The development promises to advance the study of typhoid and the creation of new vaccines against the infection, which remains a major health threat in developing countries.

26 Oct 2012

Researchers track spread of human invasive non-Typhoidal Salmonella in sub-Saharan Africa

A new study out today (Sunday 30 September) reveals that the emergence and spread of a rapidly evolving invasive intestinal disease, that has a significant mortality rate (up to 45%) in infected people in sub-Saharan Africa, seems to have been potentiated by the HIV epidemic in Africa.

1 Oct 2012

RapidChek- SELECT Salmonella highly sensitive to the presence of S. Typhi vaccine in stool

Salmonella Typhi (S. Typhi) is the causative agent of typhoid fever, a serious health threat resulting in some 22 million new cases yearly and approximately 217,000 fatalities. A number of novel vaccine candidates using live attenuated strains of Salmonella are being developed, but care must be taken to ensure the bacteria are not excreted into the environment following vaccination.

29 Jun 2012

Wellcome Trust awards University of Maryland $4M to accelerate development of conjugate NTS vaccine

The University of Maryland School of Medicine's Center for Vaccine Development (CVD) has received a $4 million Strategic Translation Award from the prestigious Wellcome Trust to support a collaboration with Bharat Biotech for clinical development of a new conjugate vaccine to prevent the potentially lethal infectious disease caused by invasive non-typhoidal Salmonella.

18 Jun 2012

Zinc supplementation in young children with serious infections significantly lowers risk of treatment failure

Treating young children with suspected serious bacterial infection with zinc in addition to standard antibiotics significantly reduces the likelihood of treatment failure, according to new research published Online First in The Lancet. In 2010, worldwide, infections were responsible for nearly two-thirds of deaths in children under 5, with around two-fifths of deaths occurring within the first month of life.

1 Jun 2012

Comprehensive approach needed to combat typhoid in Africa, worldwide

Though the focus on typhoid fever traditionally has focused on Asia, where the disease is endemic, "[s]ince early November 2011, there has been a surge of typhoid fever outbreaks in central and southern Africa, affecting children and adults alike," Christopher Nelson, director of the Coalition against Typhoid (CaT) at the Sabin Vaccine Institute, and Ciro de Quadros, executive vice president of the Sabin Vaccine Institute, write in this Atlantic opinion piece.

6 Apr 2012

Water scarcity may cause global instability, U.S. intelligence agencies say in report

U.S. intelligence agencies released a report on Thursday warning that "[d]rought, floods and a lack of fresh water may cause significant global instability and conflict in the coming decades, as developing countries scramble to meet demand from exploding populations while dealing with the effects of climate change," the Associated Press reports.

23 Mar 2012

Typhoid outbreak spreading in Zimbabwe; Officials working to improve sanitation, drug supply

"A typhoid outbreak that began in Harare last year is steadily spreading across Zimbabwe with more than 3,000 cases reported although only one death due to the disease has been reported so far, health officials have said," ZimOnline reports.

1 Mar 2012

Typhoid on Christmas Island

As of now people seeking asylum on Christmas Island will have to wait to be transferred to mainland Australia, after typhoid fever was detected on the island.

27 Feb 2012

Zimbabwean officials call for improvements to water, sanitation systems to prevent further typhoid outbreaks

Zimbabwean health officials responding to typhoid outbreaks in the capital of Harare that have affected more than 2,000 people "have called on the local and central governments to overhaul water and sanitation systems" to stem the spread of the disease, VOA News reports.

16 Feb 2012

Water-associated disease outbreaks more likely to occur in high population density areas

Water-associated infectious disease outbreaks are more likely to occur in areas where a region's population density is growing, according to a new global analysis of economic and environmental conditions that influence the risk for these outbreaks.

15 Feb 2012

Fears of cholera outbreak arise in Zimbabwe after more than 800 cases of typhoid reported

"Doctors in Zimbabwe said more than 800 cases of typhoid have been reported in Harare, the capital, in an outbreak of the bacterial disease," GlobalPost reports.

31 Jan 2012

Government, humanitarian agencies respond to flooding in Philippines, warn of disease threat

"Philippine authorities are warning of the spread of diseases in cramped evacuation centers, days after flash floods hit the southern Philippines and claimed more than a thousand lives," ABC/Asia Pacific News reports, noting that flooding also has affected the country's northern provinces, displacing at least 50,000 people.

22 Dec 2011

Research into how flying fox spreads infectious diseases

The flying fox is an adorable doe-eyed bat with a dark side - it is the perfect vector for emerging infectious diseases from Asia. Susan Tsang, a PhD student in ecology and evolutionary biology at The City College of New York and the CUNY Graduate Center, turned to a revolutionary way to help fund her research into how this species spreads disease.

21 Dec 2011

Link between malaria and salmonella infections

The link between malaria and salmonella infections has been explained for the first time, opening the way to more effective treatments.

19 Dec 2011

U.N. seeks aid money for Zimbabwe, half for food; WHO says country must spend more on health

"The United Nations said on Friday it was seeking $268 million for aid efforts in Zimbabwe next year, with half the money to be used to buy food for more than 1.4 million people facing shortages" in 2012, Reuters reports.

13 Dec 2011

HVTN debunks top 10 myths about HIV vaccine research

Dec. 1 is World AIDS Day, and in commemoration of the occasion, the HIV Vaccine Trials Network, headquartered at Fred Hutchinson Cancer Research Center, debunks the top 10 myths about HIV vaccine research.

18 Nov 2011

Health officials report more than 200 cases of typhoid in Zimbabwe's capital

"Health authorities say 207 cases of typhoid are being treated in Zimbabwe's capital after a prolonged spell of unusually hot weather amid acute water shortages," the Associated Press/Seattle Times reports. Prosper Chonzi, Harare city council health director, "said Tuesday the disease will be difficult to contain in impoverished townships relying on water from shallow, makeshift wells and marshlands," and that "humanitarian agencies have been asked to help provide clean water," the news service writes.

17 Nov 2011