Valine News and Research

RSS

New sensor may be deployed to screen patients for hard-to-diagnose cancers

Drawing inspiration from natural sensory systems, an MIT-led team has designed a novel sensor that could detect the same molecules that naturally occurring cell receptors can identify.

21 Jul 2023

Elucidating the role of the gut-brain-axis in autism

The study investigates the relationship between the gut and the brain in autism spectrum disorder (ASD), identifying microbial profiles and metabolic products associated with ASD phenotypes, dietary patterns, and inflammation. The findings provide insights into the role of the gut-brain axis in ASD and its potential impact on understanding and managing the disorder.

28 Jun 2023

Leucine deficient diet has antidepressant effects on chronic restraint stress-induced depression-like behaviors

Depression is a leading cause of disability around the world and contributes greatly to the global burden of disease.

6 Jun 2023

The phenolic composition, antioxidant capacity, and other functional properties of fresh and dried figs

Researchers explored the phytochemical contents and health benefits of consuming figs.

6 Jun 2023

Shaping the human metabolome: the impact of a ketogenic diet

Researchers explored how the human metabolic fingerprint changes with a ketogenic diet (KD).

6 Jun 2023

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

The gene ECHS1 encodes for enoyl-CoA hydratase short-chain 1, a mitochondrial enzyme involved in branched-chain amino acid and fatty acid metabolism.

18 May 2023

Ketogenic diet: A metabolic makeover boosting immunity and battling inflammation

A recent study discusses alterations in the human metabolic fingerprint associated with the keto diet.

8 May 2023

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

In a recent study published in the Journal of the Alzheimer's Association (AA), researchers examined the effects of a low-carbohydrate-modified Mediterranean ketogenic diet (MMKD) on the gut microbiome and metabolome of patients at risk for Alzheimer's disease (AD).

9 Apr 2023

JPL study uses metagenomic sequencing to monitor microbial burden on spacecraft

A recent study published in PLOS ONE uses metagenomics to examine the microbial composition in samples obtained from the Jet Propulsion Laboratory.

28 Mar 2023

Leucine deprivation results in antidepressant effects, study shows

Depression is a leading cause of disability around the world and contributes greatly to the global burden of disease.

3 Mar 2023

Mass spectrometry-based identification of COVID-19 biomarkers

In a recent study published in the journal Metabolites, researchers reported that mass spectrometry (MS)-based metabolomic approaches have a high potential for biomarker discovery.

28 Feb 2023

What is the effect of maternal circulating amino acids on offspring birthweight?

Researchers examined the effect of serum levels of 20 amino acids in a mother during pregnancy on offspring birthweight in a two-sample summary data Mendelian randomization framework.

27 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

Can diets reverse or delay aging?

A new study published in the journal Science aimed to summarize the commonly studied anti-aging dietary interventions and their impact on human health and longevity.

10 Jan 2023

New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture systems

In a recent study posted to the bioRxiv* preprint server, researchers at Emory University used severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Washington (WA.1) and Omicron (BA.1) strains to test for mutations that could result in resistance to the antiviral drug nirmatrelvir.

8 Jan 2023

XBB Omicron variant evades vaccine-induced immunity

A new study published in The Lancet Microbe examines the immune evasion characteristics of the Omicron XBB subvariant.

12 Dec 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

Valine News and Research

New sensor may be deployed to screen patients for hard-to-diagnose cancers

Elucidating the role of the gut-brain-axis in autism

Leucine deficient diet has antidepressant effects on chronic restraint stress-induced depression-like behaviors

The phenolic composition, antioxidant capacity, and other functional properties of fresh and dried figs

Shaping the human metabolome: the impact of a ketogenic diet

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

Ketogenic diet: A metabolic makeover boosting immunity and battling inflammation

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

JPL study uses metagenomic sequencing to monitor microbial burden on spacecraft

Leucine deprivation results in antidepressant effects, study shows

Mass spectrometry-based identification of COVID-19 biomarkers

What is the effect of maternal circulating amino acids on offspring birthweight?

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Can diets reverse or delay aging?

New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture systems

XBB Omicron variant evades vaccine-induced immunity

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

New engineered peptides could prevent the superbug crisis

SARS-CoV-2 mutational spectra based on reconstructed phylogenetic tree

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

Latest News