Vascular News and Research

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Positive interim results from Nereus Pharmaceuticals' plinabulin VDA study for advanced NSCLC

Nereus Pharmaceuticals, Inc., a pioneer in drug discovery from marine microbial sources, today announced positive interim results from a randomized Phase 2 clinical trial evaluating the vascular disrupting agent (VDA) plinabulin (NPI-2358) in combination with standard chemotherapy (docetaxel) in patients with advanced non-small cell lung cancer (NSCLC).

23 Nov 2009

100th patient enrolled in Atrium Medical's iCAST Atrium Registry Ultrasound Study

Atrium Medical Corporation announced that the 100th patient was enrolled in the iCAST™ Atrium Registry Ultrasound Study (iCARUS). The iCARUS study is a prospective, multi-center clinical trial studying the safety and efficacy of the Atrium iCAST™ Balloon Expandable Covered Stent in patients with occlusive disease in the iliac artery.

23 Nov 2009

New target may promote development of novel therapies for chronic sinusitis

A protein known to stimulate blood vessel growth has now been found to be responsible for the cell overgrowth in the development of polyps that characterize one of the most severe forms of sinusitis, a study by Johns Hopkins researchers suggests. The finding gives scientists a new target for developing novel therapies to treat this form of the disease, which typically resists all current treatments.

23 Nov 2009

Review of study presented at American Heart Association Scientific Sessions

Adding the cholesterol drug niacin to a statin improved HDL ("good") cholesterol levels and significantly reduced carotid arterial plaque buildup measured with ultrasound within 8 months, with further improvement seen at the end of the study (14 months).

21 Nov 2009

Cardio Vascular Medical Device to initiate patent applications for its "steerable guidewire" in Europe

Cardio Vascular Medical Device Corp., a leading developer of advanced cardiovascular surgery technology, today announced that the company's Board of Directors has decided to initiate patent applications in Europe, Canada and the Far East for its proprietary next-generation "steerable guidewire" applicable for all angioplasty (PCTA) procedures.

21 Nov 2009

First-quarter fiscal 2010 results announced by Escalon Medical

Escalon Medical Corp. announced the results for its fiscal first quarter ended September 30, 2009.

20 Nov 2009

UCH’s Cardiac & Vascular Center now offers treatment with CardiacAssist's TandemHeart System

CardiacAssist Inc. announced today that the University of Colorado Hospital (UCH) has adopted the company’s TandemHeart® System.

20 Nov 2009

Pfizer’s Revatio Injection receives FDA approval

Pfizer announced today that the U.S. Food and Drug Administration (FDA) has approved Revatio® (sildenafil) Injection, an intravenous formulation of Revatio. Revatio is the only FDA-approved phosphodiesterase-5 (PDE5) inhibitor available in both tablet and intravenous formulations.

20 Nov 2009

Medtronic introduces imaging and visualization service for endovascular specialists

Continuing to drive innovation in endovascular aortic repair (EVAR), Medtronic, Inc., today announced the introduction of an imaging and visualization service for endovascular specialists who use the company’s market-leading portfolio of stent grafts to treat aortic aneurysms. Aortic aneurysms affect more than one million people in the United States alone and can rupture with fatal consequences if left untreated.

19 Nov 2009

Experts to study how olive oil lowers the level of cytotoxicity in endothelial cells

Experts at Virgen del Rocío Hospital (Seville, Spain) have begun a study on pregnancy preeclampsia on a sample of 30 pregnant women with a view to demonstrating whether or not consumption of olive oil by this population group results in lower levels of cytotoxicity (for example, cholesterol) in endothelial cells (arterial wall cells).

19 Nov 2009

Toddlers and obese children suffer more than youth when exposed to secondhand smoke

Toddlers and obese children suffer more than other youth when exposed to secondhand smoke, according to research presented at the American Heart Association's Scientific Sessions 2009.

19 Nov 2009

Joint project focuses on finding ways to prevent dementia, including Alzheimer's disease

Every two years, 2,000 senior Group Health patients check in with the Adult Changes in Thought (ACT) study. The joint project between Group Health Research Institute and the University of Washington (UW) focuses on finding ways to delay or prevent dementia, including Alzheimer's disease, and declines in memory and thinking.

19 Nov 2009

Opiate-based painkillers can increase tumor-cell proliferation, says new study

Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells.

19 Nov 2009

Results from Phase IIa clinical trial evaluating VT-111 reported by Viron Therapeutics

Viron Therapeutics Inc., a biotechnology company pioneering the development of immune-modulating protein therapeutics derived from pathogens, today reported results from a Phase IIa clinical trial evaluating VT-111 (Serp-1), an anti-inflammatory protein derived from the myxoma virus.

19 Nov 2009

Dual niacin-statin therapy improves blood cholesterol levels but does not diminish plaque buildup

The routine prescription of extended-release niacin, a B vitamin (1,500 milligrams daily), in combination with traditional cholesterol-lowering therapy offers no extra benefit in correcting arterial narrowing and diminishing plaque buildup in seniors who already have coronary artery disease, a new vascular imaging study from Johns Hopkins experts shows.

19 Nov 2009

Endologix receives IDE conditional approval from FDA

Endologix, Inc., developer of minimally invasive treatments for aortic disorders, announced today that it has received Investigational Device Exemption (IDE) conditional approval from the United States Food and Drug Administration ("FDA") to begin a prospective, multicenter, randomized clinical trial for a bilateral percutaneous approach to endovascular abdominal aortic aneurysm repair (EVAR) utilizing the Company's IntuiTrak(TM) endovascular delivery system for the Powerlink® family of stent grafts.

19 Nov 2009

New pre-clinical data from Alnylam Pharmaceuticals' ALN-VSP program presented

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, today announced new pre-clinical data from its ALN-VSP program presented at the AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics International conference being held November 15 - 19, 2009 in Boston, Mass.

18 Nov 2009

Ambrisentan improves health and exercise capacity of PAH patients, find researchers

In one of the few studies of the long-term effects of medication in the treatment of pulmonary arterial hypertension (PAH) disease, a team of researchers found the health and exercise capacity of PAH patients improved after two years of treatment with ambrisentan, according to a study published in the current edition of the Journal of the American College of Cardiology.

18 Nov 2009

Press conference highlights emerging treatments in pancreatic cancer

As part of the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Thompson will moderate a press conference on emerging treatments in pancreatic cancer on Tuesday, Nov. 17, 2009, in Room 202 of the Hynes Convention Center in Boston, Mass., from 1:00 p.m. to 2:00 p.m. ET.

18 Nov 2009

Study to test anti-tumor effects of AEOL 10150 initiated

Aeolus Pharmaceuticals, Inc. announced today the initiation of a study to test the anti-tumor effects of AEOL 10150 when combined with radiation and chemotherapy in nude mice bearing human non-small cell lung cancer (NSCLC) xenografts.

18 Nov 2009

Vascular News and Research

Positive interim results from Nereus Pharmaceuticals' plinabulin VDA study for advanced NSCLC

100th patient enrolled in Atrium Medical's iCAST Atrium Registry Ultrasound Study

New target may promote development of novel therapies for chronic sinusitis

Review of study presented at American Heart Association Scientific Sessions

Cardio Vascular Medical Device to initiate patent applications for its "steerable guidewire" in Europe

First-quarter fiscal 2010 results announced by Escalon Medical

UCH’s Cardiac & Vascular Center now offers treatment with CardiacAssist's TandemHeart System

Pfizer’s Revatio Injection receives FDA approval

Medtronic introduces imaging and visualization service for endovascular specialists

Experts to study how olive oil lowers the level of cytotoxicity in endothelial cells

Toddlers and obese children suffer more than youth when exposed to secondhand smoke

Joint project focuses on finding ways to prevent dementia, including Alzheimer's disease

Opiate-based painkillers can increase tumor-cell proliferation, says new study

Results from Phase IIa clinical trial evaluating VT-111 reported by Viron Therapeutics

Dual niacin-statin therapy improves blood cholesterol levels but does not diminish plaque buildup

Endologix receives IDE conditional approval from FDA

New pre-clinical data from Alnylam Pharmaceuticals' ALN-VSP program presented

Ambrisentan improves health and exercise capacity of PAH patients, find researchers

Press conference highlights emerging treatments in pancreatic cancer

Study to test anti-tumor effects of AEOL 10150 initiated

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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