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Poor inflammatory immune response in obese patients increases susceptibility to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

20 Mar 2023

Study finds community-onset bacterial coinfection in children with critical COVID-19 is infrequent but empiric antibiotics are commonly prescribed

Researchers evaluated the use of empiric antibiotics to determine the prevalence rates of community-acquired bacterial coinfections among hospitalized pediatric critical COVID-19 patients.

8 Mar 2023

The safety of short-course compared to long-course antibiotic therapy for ventilator-associated pneumonia

Researchers performed a meta-analysis of randomized controlled trials to evaluate the safety of short-course antibiotic treatment versus long-course antibiotic treatment for ventilator-associated pneumonia.

7 Mar 2023

25% of COVID-19 patients have lasting reduction in lung function

In a recent study posted to the Preprints with The Lancet SSRN* server, researchers evaluated the impairment of pulmonary function in individuals suffering from post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) or long coronavirus disease (long COVID) symptoms after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

28 Feb 2023

California requires hospitals to turn to a patient’s next of kin, closing a longtime loophole

About four years ago, Dr. Gene Dorio sat on the ethics committee of a Southern California hospital whose administrators insisted they could decide whether to disconnect a ventilator from an unconscious patient — even though the man's wife and adult children wanted to continue life support.

17 Feb 2023

As opioids mixed with animal tranquilizers arrive in Kensington, so do alarming health challenges

Many people living on the streets in Philadelphia's Kensington neighborhood — the largest open-air drug market on the East Coast — are in full-blown addiction, openly snorting, smoking, or injecting illicit drugs, hunched over crates or on stoops. Syringes litter sidewalks, and the stench of urine fouls the air.

15 Feb 2023

Rockefeller scientists describe the genetics of severe SARS-CoV-2 infection in children

One of the most terrifying aspects of the COVID pandemic has been its unpredictably severe impact on some children.

10 Feb 2023

Comparison of pre- and post-Omicron disease severity among unvaccinated people without risk factors

In a recent study posted to the medRxiv* preprint server, researchers in Sweden investigated coronavirus disease 2019 (COVID-19) severity among unvaccinated adults during the periods of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) dominance compared to the severity of pre-Omicron VOC infections.

8 Feb 2023

Pregnancy outcomes after monoclonal antibodies infusion for COVID-19

Researchers evaluated the impact of monoclonal antibodies against SARS-CoV-2 on maternal-fetal health.

8 Feb 2023

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

A baby spent 36 days in an in-network NICU. Why did the hospital next door send a bill?

Brenna Kearney was seven months pregnant in December 2019 when she experienced what she thought were bad flu symptoms.

30 Jan 2023

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Researchers have designed the first 'living medicine' to treat lung infections. The treatment targets Pseudomonas aeruginosa, a type of bacteria which is naturally resistant to many types of antibiotics and is a common source of infections in hospitals.

19 Jan 2023

Novel peptide suppresses the damaging lung inflammation seen in ARDS

A novel peptide designed by University of California, Irvine researchers has been found to suppress the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS.

17 Jan 2023

COVID-19 is a threat during pregnancy, study suggests

Pregnant women who are infected with the virus that causes COVID-19 face a 7 times increased risk of dying and a significantly elevated risk of being admitted to an intensive care unit or suffering from pneumonia, according to research published today in BMJ Global Health.

17 Jan 2023

Does COVID-19 pneumonia have a higher mortality rate than other causes of pneumonia?

A recent study evaluated outcomes in mechanically ventilated patients with pneumonia due to COVID-19 or other etiologies.

13 Jan 2023

‘Caged … for no fault of your own’: Detainees dread covid while awaiting immigration hearings

In October, Yibran Ramirez-Cecena didn't alert the staff at Stewart Detention Center to his cough and runny nose.

22 Dec 2022

'Stem cell plasters' could revolutionize treatment for children with congenital heart disease

Researchers at the University of Bristol funded by the British Heart Foundation (BHF) have developed 'stem cell plasters' to revolutionize the way surgeons treat children living with congenital heart disease, so they don't need as many open-heart operations.

20 Dec 2022

Severe COVID-19 causes aging-like changes in the human brain

Severe COVID-19 triggers aging-like changes in the brain's frontal cortex region that results in cognitive deficits.

11 Dec 2022

Machine learning analysis suggests that there are four sub-phenotypes of long COVID

Researchers identified PASC [post-acute sequelae of coronavirus disease 2019 (COVID-19)] sub-phenotypes depending on conditions diagnosed within 1 to 3 months of acute infection by SARS-CoV-2.

6 Dec 2022

Is remdesivir treatment associated with reduced risk of inpatient mortality among US patients hospitalized with COVID-19?

Researchers assessed the effect of remdesivir on inpatient COVID-19-associated mortality among individuals hospitalized with SARS-CoV-2 infections in an enormous dataset of US residents beyond clinical trial settings.