Viral Vector News and Research

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Viral Vector is a type of virus used in cancer therapy. The virus is changed in the laboratory and cannot cause disease. Viral vectors may produce tumor antigens (proteins found on a tumor cell) to stimulate an antitumor immune response in the body. Viral vectors may also be used to carry genes that can change cancer cells back to normal cells.

Vector Biolabs expands viral vector manufacturing capacity and adds to QC capabilities

Vector Biolabs, a custom design and manufacturing service provider for AAV and adenovirus viral vectors announced the completion of a facility expansion to meet growing demand.

12 May 2023

New technology can deliver gene therapy directly to the lung

Scientists at UMass Chan Medical School have developed a technology to deliver gene therapy directly to lung tissue through intranasal administration, a development that could potentially create a new class of treatments for lung disease.

2 May 2023

Researchers identify regions of the viral envelope of simian foamy viruses targeted by neutralizing antibodies

A recent study characterized epitopes recognized by neutralizing antibodies from individuals infected with simian foamy virus.

26 Apr 2023

Gene therapy approach can decrease intraocular pressure in pre-clinical models of glaucoma

Scientists at Trinity College Dublin today announced a significant development towards a new therapeutic treatment of glaucoma.

19 Apr 2023

Overcoming challenges in flavivirus vaccine development: Exploring modern vaccine types for Dengue, Zika, and beyond

Researchers discuss the challenges impeding the development of vaccines against flaviviruses.

4 Apr 2023

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

In a recent study posted to the bioRxiv* preprint server, researchers in Italy and the United States evaluated the efficacy and immunogenicity of an adjuvanted tetravalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit 1 (S1) COVID-19 vaccine.

21 Mar 2023

How effective are monovalent mRNA COVID-19 vaccine booster doses against Omicron-associated severe outcomes among adults?

Researchers from Canada investigated the efficacy of booster doses of the monovalent mRNA COVID-19 vaccine in preventing hospitalization and death during the dominance of the SARS-CoV-2 Omicron variant.

10 Mar 2023

Exploring COVID-19 immunization speed and timing in Africa

A new BMC Medicine study retrospectively analyzed the impact of COVID-19 vaccination timing and speed on the virus transmission in 27 African countries, based on a combined epidemiological and economic modeling approach. The authors aimed to inform future decisions about vaccine roll-out and investment.

10 Mar 2023

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

Researchers performed a meta-analysis analyzing randomized controlled trials (RCTs) that evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines, and the dose-response association of humoral responses with vaccine effectiveness.

6 Mar 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

COVID-19 vaccination associated with fewer heart attacks, strokes, and other cardiovascular issues

Analyzing the most extensive datasets in the United States, researchers from the Icahn School of Medicine at Mount Sinai have revealed that vaccination against COVID-19 is associated with fewer heart attacks, strokes, and other cardiovascular issues among people who were infected with SARS-CoV-2, the virus that causes COVID-19.

20 Feb 2023

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Researchers at Children's Hospital Los Angeles have received a nearly $1 million K08 grant from the National Institutes of Health (NIH)-; as well as funding from the U.S. Department of Defense-;to support studies into diffuse intrinsic pontine glioma (DIPG), a childhood brain tumor with a 0% survival rate.

16 Feb 2023

Behavioral deficits associated with chronic stress involve impaired neurosteroid synthesis and signaling

The latest generation of antidepressants relieves symptoms by mimicking steroids produced by the brain to ensure neurons are effectively talking to each other.

13 Feb 2023

SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination

Researchers examined the factors associated with stroke following coronavirus disease 2019 (COVID-19) vaccination.

13 Feb 2023

Study shows that SARS-CoV-2 infection is associated with an increased risk for maternal morbidity and severe complications

Researchers examined vaccine effectiveness and pregnancy outcomes during the SARS-CoV-2 Omicron period.

23 Jan 2023

Vaccinated women well protected against severe COVID-19 symptoms, complications during pregnancy

The global network led by the Oxford Maternal and Perinatal Health Institute (OMPHI) at the University of Oxford has today published, in the Lancet, the results of the '2022 INTERCOVID Study' conducted in 41 hospitals across 18 countries.

19 Jan 2023

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

Researchers performed an observational study among COVID-19 patients and their close contacts registered with the Bangkok home health care services in Thailand.

18 Jan 2023

FUJIFILM Irvine Scientific launches HEK293 Feed, specifically designed for viral vector production

FUJIFILM Irvine Scientific, Inc., a world leader in the development and manufacture of serum-free and chemically defined cell culture media for bioproduction and cell therapy manufacturing, today announced the launch of its BalanCD HEK293 Viral Feed.

11 Jan 2023

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

A new study aimed to analyze whether the order of immunization of vaccine types impacted the efficacy of a heterologous prime-boost vaccination strategy.

6 Jan 2023

Decoding nucleic acid-based drugs and vaccines through SEC-SLS analysis

In this interview, Malvern Panalytical’s Product Technical Specialist, Stefan Cairns, discusses how SEC-SLS can be used to understand MRNA vector composition by referencing his latest publication.

From Malvern Panalytical 19 Dec 2022