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Cells use liquid droplets to regulate signaling pathways, study finds

Healthy cells respond appropriately to changes in their environment. They do this by sensing what's happening outside and relaying a command to the precise biomolecule in the precise domain that can carry out the necessary response.

22 Apr 2024

ApoA-IV surge after bariatric surgery enhances insulin secretion and energy expenditure

Bariatric surgery has emerged as an effective means of reducing weight in morbidly obese individuals, while also significantly improving diabetes. Currently, laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (RYGB) are two of the most commonly performed bariatric surgeries.

18 Apr 2024

Conservative justices stir trouble for Republican politicians on abortion

Abortion opponents have maneuvered in courthouses for years to end access to reproductive health care. In Arizona last week, a win for the anti-abortion camp caused political blowback for Republican candidates in the state and beyond.

16 Apr 2024

Cancer risk elevated in families with male infertility

In a recent study, researchers at Huntsman Cancer Institute at the University of Utah (the U) found a surprising trend in families with male infertility: an increased risk of certain cancers.

9 Apr 2024

Mechanical pressure revealed as key factor in embryonic organ formation

A collaboration between research groups at the University of California, TU Dresden in Germany and Cedars-Sinai Guerin Children's in Los Angeles has identified a mechanism by which embryonic cells organize themselves to send signals to surrounding cells, telling them where to go and what to do.

3 Apr 2024

DNA repair process key to memory formation, study finds

Study reveals that learning triggers a series of molecular events including DNA damage and repair in hippocampal neurons, mediated by TLR9, crucial for memory formation.

31 Mar 2024

New hope for binge eating and bulimia: GLP-1 drugs could be the key

GLP-1 receptor agonists show promise in reducing binge eating behaviors in disorders like bulimia nervosa, offering a new avenue for treatment with minimal side effects.

4 Mar 2024

California Gov. Newsom wants voters to approve billions more to help the homeless. Will it help?

California voters will decide March 5 whether to pump billions more dollars into combating the nation's worst homelessness crisis, an investment Democratic Gov. Gavin Newsom argues will finally provide the housing and treatment so badly needed by tens of thousands of homeless people.

26 Feb 2024

Tiny device could help improve safety, effectiveness of cell therapy for spinal cord injury patients

A tiny device built by scientists at MIT and the Singapore-MIT Alliance for Research and Technology could be used to improve the safety and effectiveness of cell therapy treatments for patients suffering from spinal cord injuries.

7 Feb 2024

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

AMG 133, an engineered bispecific molecule, demonstrated significant weight loss with a favorable safety profile in a phase 1 clinical trial, offering a promising new treatment option for obesity.

7 Feb 2024

Johns Hopkins scientists unravel mystery of retinal cell communication

Working with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that, unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different pathways at the same time to transmit electrical "vision" signals to the brain.

25 Jan 2024

Key protein EPAC1 found to regulate brown fat growth, offering obesity treatment potential

Study reveals that EPAC1 protein plays a crucial role in regulating the growth of brown and beige adipose tissue, offering potential avenues for treating obesity and improving cardiometabolic health.

11 Jan 2024

Inside the Pentagon’s painfully slow effort to clean up decades of PFAS contamination

Oscoda, Michigan, has the distinction as the first community where "forever chemicals" were found seeping from a military installation into the surrounding community.

21 Dec 2023

‘I am just waiting to die’: Social Security clawbacks drive some into homelessness

More than a year after the federal government first cut off her disability benefits, Denise Woods drives nightly to strip malls, truck stops, and parking lots around Savannah, Georgia, looking for a safe place to sleep in her Chevy.

20 Dec 2023

Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Dietary components that impact anti-tumor immunity.

28 Nov 2023

Novel method can detect contaminants in T-cell cultures within 24 hours

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, in collaboration with Singapore Centre for Environmental Life Sciences Engineering (SCELSE) and Massachusetts Institute of Technology (MIT), have developed a novel method capable of identifying contaminants in T-cell cultures within 24 hours.

27 Nov 2023

Groundbreaking technology developed to extract mesenchymal stem cells from pure bone marrow

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with the Agency for Science, Technology and Research (A*STAR) Bioprocessing Technology Institute (BTI) and National University Health System (NUHS), have developed a groundbreaking technology capable of extracting mesenchymal stem cells (MSCs) directly from pure bone marrow – also known as bone marrow aspirate (BMA), a pivotal source of MSCs – without dilution.

20 Nov 2023

New study sheds light on the genes and nutrients that give MAIT cells their fighting power

Scientists at La Jolla Institute for Immunology (LJI) are investigating a talented type of T cell.

10 Nov 2023

Novel and emerging therapies offer new hope for patients with inflammatory bowel disease

Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases (IBD) that affect the gastrointestinal tract.

7 Nov 2023

How caffeine impacts cerebral blood flow

Caffeine consumption affects cerebral blood flow in young adults, with the study showing a dose-dependent reduction in arterial velocity post-intake. This impact on the cardiovascular system suggests caffeine's vasodilatory effects on cerebral arteries.

5 Nov 2023