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Simple biomechanical test can help analyze tissue implant quality

The quality of the tissue-implant interface is key to the success of implant integration. High-output benchtop screening can help developers in assessing the complex interplay between biomaterials and the body to better prepare for clinical trials, highlights a review in the journal Science and Technology of Advanced Materials.

10 Oct 2017

University of Akron researcher awarded NSF grant to study bone remodeling

Osteoporosis is a disease categorized by brittle bones and increased risk of fracture. Individuals with osteoporosis, and diseases like it, have access to a number of treatments but no permanent solution.

9 Oct 2017

Penn study explains how acute viral infections can linger

Infections caused by viruses, such as respiratory syncytial virus, or RSV, measles, parainfluenza, and Ebola, are typically considered acute. These viruses cause disease quickly and live within a host for a limited time. But in some cases, the effects of the infection, and presence of the virus itself, can persist.

6 Oct 2017

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Preeclampsia is the most dangerous form of hypertension during a pregnancy and can be fatal for both mother and child. Though it is known to originate in the placenta, the root causes remain largely a mystery.

6 Oct 2017

ITL Group returns to MEDICA 2017 to discuss future of diagnostic devices

Leading medical device design and manufacturing company, ITL Group returns to the MEDICA tradeshow in Düsseldorf, Germany this November with a simple message – ‘your future rests with us.’

From Vitl Life Science Solutions 6 Oct 2017

Researchers discover circadian clock at work in our muscles

Biological clocks are ticking everywhere throughout our body. They trigger the release of the hormone melatonin during sleep, favour the secretion of digestive enzymes at lunchtime or keep us awake at the busiest moments of the day.

3 Oct 2017

Studies shed new light on leading cause of birth defects and miscarriage

Two recent Northwestern University studies shed new light on the mystery of the leading cause of birth defects and miscarriage, laying the foundation for further research in an understudied but crucially important field of genetic study.

3 Oct 2017

FDA approves FreeStyle Libre Flash Glucose Monitoring System for adult patients with diabetes

The U.S. Food and Drug Administration today approved the FreeStyle Libre Flash Glucose Monitoring System, the first continuous glucose monitoring system that can be used by adult patients to make diabetes treatment decisions without calibration using a blood sample from the fingertip.

27 Sep 2017

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Merck KGaA, Darmstadt, Germany, and Pfizer Inc. today announced that the Japanese Ministry of Health, Labor, and Welfare (MHLW) has approved BAVENCIO (avelumab, genetically recombinant Injection 200mg/mL for intravenous use) as the first and only treatment indicated for curatively unresectable Merkel cell carcinoma (MCC), a rare and aggressive cancer, in Japan.

27 Sep 2017

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Chagas disease is a potentially life-threatening illness caused by the parasite, Trypanosoma cruzi, and is transmitted to humans through triatomine blood-sucking bugs that are commonly referred to as "kissing bugs" or "vampire bugs".

26 Sep 2017

Study presents new method for tracing history of β-cells

Tracing the history of individual cells in the developing organism can reveal functional differences among seemingly uniform cells. This knowledge is important for defining the characteristics of highly regenerative cells in order to target them for cellular therapies, as well as to prevent the formation of unfit cells, which compromise the overall health of the organism.

22 Sep 2017

Researchers identify exosomes as missing link to insulin resistance in type 2 diabetes

Chronic tissue inflammation resulting from obesity is an underlying cause of insulin resistance and type 2 diabetes. But the mechanism by which this occurs has remained cloaked, until now.

21 Sep 2017

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Fungal infections represent an increasing health crisis, especially for immune-deficient patients. American scientists now report in the journal Angewandte Chemie that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action.

21 Sep 2017

'Small intestinal permeable peptides' improve biopharmaceuticals absorption in digestive tract

Biopharmaceuticals, medium- and high-molecular weight biologically active macromolecules, are not easily absorbed by the small intestine, the main organ responsible for gastrointestinal absorption, resulting in a bottleneck for oral administration type biopharmaceutical development.

20 Sep 2017

Scientists take important step toward gene therapy for deaf patients

Scientists at Oregon State University have taken an important step toward gene therapy for deaf patients by developing a way to better study a large protein essential for hearing and finding a truncated version of it.

19 Sep 2017

Research unravels how stem cells in the ovaries may be harnessed to revolutionize fertility treatments

About 13 years ago, Northeastern professor Jonathan Tilly, a reproductive biologist, made a discovery that challenged everything scientists thought they knew about female reproduction. The long-held belief that mammals were born with a set number of eggs -- and no ability to create new ones -- was wrong.

15 Sep 2017

Nanoparticle bling could increase sensitivity of test strips for better cancer detection

The most common test strip people might think of for diagnosis is a home pregnancy test. Pregnant women have steadily increasing levels of the biomarker human chorionic gonadotropin (hCG), which is easily detectable in urine and a thin, colorful strip of antibodies will appear when hCG is present.

13 Sep 2017

Study confirms tattoo nanoparticles migrate around the body

A study conducted by a team of scientists from Germany and the European Synchrotron Radiation Facility (ESRF), France, found that the elements which constitute the tattoos’ ink reach the lymph nodes by travelling inside the body in micro and nanoparticle forms.

13 Sep 2017

Japanese researchers find new way for increasing effectiveness of drug delivery to brain tumors

For a cancer drug to be successful, it needs to reach the malignant tumor site. Researchers in Japan have now found a way for increasing the effectiveness of drug delivery to certain types of brain tumors, by packing epirubicin, a known antitumor agent, in specially designed polymeric micelles.

13 Sep 2017

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models.

13 Sep 2017

in vitro News and Research

Simple biomechanical test can help analyze tissue implant quality

University of Akron researcher awarded NSF grant to study bone remodeling

Penn study explains how acute viral infections can linger

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

ITL Group returns to MEDICA 2017 to discuss future of diagnostic devices

Researchers discover circadian clock at work in our muscles

Studies shed new light on leading cause of birth defects and miscarriage

FDA approves FreeStyle Libre Flash Glucose Monitoring System for adult patients with diabetes

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Study presents new method for tracing history of β-cells

Researchers identify exosomes as missing link to insulin resistance in type 2 diabetes

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

'Small intestinal permeable peptides' improve biopharmaceuticals absorption in digestive tract

Scientists take important step toward gene therapy for deaf patients

Research unravels how stem cells in the ovaries may be harnessed to revolutionize fertility treatments

Nanoparticle bling could increase sensitivity of test strips for better cancer detection

Study confirms tattoo nanoparticles migrate around the body

Japanese researchers find new way for increasing effectiveness of drug delivery to brain tumors

NIH awards $15 million to develop 3D microphysiological system platforms that model human disease

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