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Research reveals opposing role for SNAP23 protein in endocrine and exocrine pancreas

Movement of secretory molecules, such as hormones and digestive enzymes, out of the cell is known as exocytosis. This process is guided by SNARE proteins, which help the fusion of secretory vesicles with the plasma membrane.

8 Dec 2016

Leti researchers show memristive devices can emulate short- and long-term synaptic plasticity

Leti researchers have demonstrated that memristive devices are excellent candidates to emulate synaptic plasticity, the capability of synapses to enhance or diminish their connectivity between neurons, which is widely believed to be the cellular basis for learning and memory.

8 Dec 2016

New chemosensor offers better sensitivity in detecting biomarker for cancer and inflammatory diseases

A new technique offers better sensitivity and accuracy in detecting an essential biomarker of cancer and inflammatory diseases.

7 Dec 2016

Starvation may shorten lifespans of children and male descendants, study suggests

New Tel Aviv University research suggests that periods of fasting or starvation may significantly shorten the lifespans of both children and their male descendants.

5 Dec 2016

MUSC researchers harness cutting-edge technology to uncover new role for pericytes during stroke

Pericytes are the primary locus of matrix-mellaproteinase-9-dependent (MMP-9) capillary damage and blood leakage during ischemia, according to preclinical findings reported by Medical University of South Carolina investigators in an article published online on November 14, 2016 by The Journal of Neuroscience.

5 Dec 2016

Researchers assess scientific rigor in animal experimentation

The "reproducibility crisis" in biomedical research has led to questions about the scientific rigor in animal research, and thus the ethical justification of animal experiments.

2 Dec 2016

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs.

1 Dec 2016

Monell Center receives Gates Foundation grant to support innovative global health research project

The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays."

1 Dec 2016

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

CRISPR/Cas9, a powerful genome editing tool, is showing promise for efficient correction of disease-causing mutations.

1 Dec 2016

Scientists synthesize antitumor compound to combat chemoresistant cancer

A team of scientists from N. D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences, N. K. Kol'tsov Institute of Developmental Biology of the RAS, and Immune Pharmaceuticals LLC led by MIPT's Prof. Alexander Kiselyov has synthesized an antitumor compound that could be used to fight chemoresistant cancer.

30 Nov 2016

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

The impassable blood-brain barrier prevents microorganisms from entering our brain, however it also blocks medicines that could help treat Parkinson's, Alzheimer's and other neurodegenerative diseases.

30 Nov 2016

MILabs to provide Adaptive X-ray CT system to UAB for advancing pulmonary research

MILabs will provide an advanced U-CTUHR microCT system to the Cystic Fibrosis Research Center (CFRC) at the University of Alabama at Birmingham (UAB).

30 Nov 2016

Particle Works develops hydrogel beads to enable 3D cell culture growth

Particle Works – the nano- and microstructured material specialist – has developed a range of alginate and agarose hydrogel beads designed to enable three dimensional cell culture growth.

30 Nov 2016

New research shows chitosan bioplastics may help seal tissue tears or other injuries

Chitosan, a biomaterial derived from the chitin shells of crustaceans and insects, has already been developed by scientists at Harvard's Wyss Institute for Biologically Inspired Engineering into an environmentally-friendly and fully biodegradable substitute for plastic.

29 Nov 2016

Scientists develop safe, highly efficient method to improve searching of new germicides

Scientists from the Lomonosov Moscow State University in cooperation with colleagues have worked out a safe, not that expensive and highly efficient method, which allows to speed up and improve searching of new germicides.

29 Nov 2016

Researchers develop new way to design glycoclusters for targeted drug delivery

A team led by researchers at the RIKEN Biofunctional Synthetic Chemistry Laboratory in Japan has developed a way to engineer glycan complexes--clusters of sugar chains attached to proteins or lipids--in a way that allows the molecules to be transported preferentially to specific organs of the body, depending on the sugar chains contained in the cluster.

29 Nov 2016

Research provides insight into molecular mechanisms involved in immune response to HBV

The innate immune system in mammals defends against infection from viruses and other microbial infections.

28 Nov 2016

Study using Cubresa SPECT scanner finds potential non-invasive diagnosis for Alzheimer’s

Cubresa’s SPECT scanner was used to determine if a novel molecular label, TRV6001, in development for in vivo imaging of the BChE enzyme present in the brains of Alzheimer’s Disease patients follows the known distribution of the enzyme in animal models of the disease.

From Cubresa Inc. 28 Nov 2016

New cell reprogramming mechanism could pave way for potential therapies to boost tissue repair

Researchers have identified a mechanism by which cells undergo reprogramming in live mice, a phenomenon that had previously been poorly understood.

24 Nov 2016

Research reveals key role of fibroblasts in development of rheumatoid arthritis

A study led by researchers at the University of Birmingham reveals the key role of different types of fibroblast cells in the development of rheumatoid arthritis (RA), opening up a new avenue for research into treatment of the disease.

23 Nov 2016

in vivo News and Research

Research reveals opposing role for SNAP23 protein in endocrine and exocrine pancreas

Leti researchers show memristive devices can emulate short- and long-term synaptic plasticity

New chemosensor offers better sensitivity in detecting biomarker for cancer and inflammatory diseases

Starvation may shorten lifespans of children and male descendants, study suggests

MUSC researchers harness cutting-edge technology to uncover new role for pericytes during stroke

Researchers assess scientific rigor in animal experimentation

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Monell Center receives Gates Foundation grant to support innovative global health research project

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

Scientists synthesize antitumor compound to combat chemoresistant cancer

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

MILabs to provide Adaptive X-ray CT system to UAB for advancing pulmonary research

Particle Works develops hydrogel beads to enable 3D cell culture growth

New research shows chitosan bioplastics may help seal tissue tears or other injuries

Scientists develop safe, highly efficient method to improve searching of new germicides

Researchers develop new way to design glycoclusters for targeted drug delivery

Research provides insight into molecular mechanisms involved in immune response to HBV

Study using Cubresa SPECT scanner finds potential non-invasive diagnosis for Alzheimer’s

New cell reprogramming mechanism could pave way for potential therapies to boost tissue repair

Research reveals key role of fibroblasts in development of rheumatoid arthritis

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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