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Genome researchers to look at 1918 Spanish flu

University of Washington researchers will be taking part in a multi-site project examining a portion of the genome of the strain of influenza responsible for the "Spanish Flu" outbreak in 1918.

20 Sep 2004

New oral gel used instead of injection to deliver drugs

Scientists in India have developed a new gel that is taken orally and is capable of delivering drugs to manage diseases often requiring an injection.

20 Sep 2004

Sinovac completes dosing in phase 1 human clinical testing of SARS vaccine

Sinovac Biotech Ltd. has announced that all 36 subjects of the Phase I human clinical trial for its inactivated SARS vaccine have now been vaccinated with two doses of either SARS vaccine or placebo.

7 Sep 2004

Phase 1 clinical trial of new anticancer drug from Human Genome Sciences

Human Genome Sciences has begun dosing patients in a Phase 1 clinical trial of HGS-TR2J, a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies.

25 Aug 2004

Researchers using light to control genes and better understand the role of certain genes in embryonic development

As our understanding of biology increases, the tools of research become almost as important as the researchers wielding them. Currently, one of the major obstacles to research is actually getting inside of cells and tissue to see what is going on as it happens.

25 Aug 2004

Regular exercise boosts immune system in older men

As it turns out, judging by the reaction strength of their immune system to an unknown, but harmless, protein antigen, it’s possible for men over 70 to mount an immune response similar to that produced by much younger men -- if they get regular moderate physical activity of about six hours a week.

25 Aug 2004

Research could lead to ways to prevent arrhythmias

The worm C. elegans seems an unlikely candidate for studies related to cardiac arrhythmias. After all, the microscopic organism doesn't even have a heart.

20 Aug 2004

No adverse side-effects have been observed in clinical trial of SARS vaccine

Sinovac Biotech has announced that all 36 subjects of the Phase I human clinical trial for its inactivated SARS vaccine have now been vaccinated with either SARS vaccine or placebo.

11 Aug 2004

First-of-its-kind noninvasive imaging technique shows two proteins interacting

Radiologists at Washington University School of Medicine in St. Louis have developed a first-of-its-kind noninvasive imaging technique that allows them to watch two proteins interacting in live animals.

2 Aug 2004

First tool to study image brain function at the cellular level

Carnegie Mellon University neuroscientist Alison Barth has developed the first tool to identify and study individual neurons activated in a living animal.

29 Jul 2004

New Caledonian sponges produce antimalarial substances

Marine organisms synthesize many different substances, some of which possess anticarcinogenic, antiviral or antiparasitic properties.

22 Jul 2004

Novel tool that can be used to visualize single neurons in living brain tissue

Carnegie Mellon University neuroscientist Alison Barth has developed the first tool to identify and study individual neurons activated in a living animal.

15 Jul 2004

Research provides new insight into the carefully controlled architectural changes that underlie organ development

A new research study demonstrates that a single chemical growth factor orchestrates a complex developmental process by sequentially activating distinct subsets of molecular signals.

13 Jul 2004

Type of cellular stress called osmotic stress is critical to cell growth and the body’s immune response against infection

Researchers at the University of California, San Diego (UCSD) School of Medicine have determined that a particular type of cellular stress called osmotic stress is of critical importance to cell growth and the body’s immune response against infection.

7 Jul 2004

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Treatment with a new dual cell cycle and angiogenesis pathway inhibitor blocks VEGF-induced vascular permeability, inhibits tumour angiogenesis and induces apoptosis in human tumour models

7 Jul 2004

Protein called Rac controls a number of biological processes and is directly implicated in several human diseases

Scientists at The Scripps Research Institute have described the regulatory mechanism of an important human protein called Rac that controls a number of biological processes and is directly implicated in several human diseases.

2 Jul 2004

Exelixis files new drug application for a proprietary novel anticancer compound

Exelixis, Inc. has submitted an investigational new drug application (IND) to the U.S. Food and Drug Administration (FDA) for XL999, a proprietary novel anticancer compound.

29 Jun 2004

WHO removes two antiretroviral products from the WHO List of prequalified products

The World Health Organization (WHO) removed two antiretroviral products from the WHO List of prequalified products

20 Jun 2004

SARS siRNA studied further to help many respiratory diseases including lung cancer

Intradigm Corporation, has announced achievement of prophylactic and therapeutic effects of siRNA (small interfering RNA) inhibitors of SARS-CoV in non-human primate cells. The results are published in the June 2004 issue of Antiviral Therapy (International Medical Press).

15 Jun 2004

Non-aspirin pain drugs may help men with recurrent prostate cancer

Early results from a University of North Carolina at Chapel Hill School of Medicine study may determine if drugs called Cox-2 inhibitors, a newer type of non-aspirin pain medicine now widely prescribed for arthritis symptoms, may benefit men with recurrent prostate cancer.

10 Jun 2004