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Amino acid nanoparticles show promise for cancer treatment

Amino acids, such as tyrosine and tryptophan, are the fundamental building blocks that make up proteins.

8 Jan 2024

Scripps scientists debunk long-held theory about alcohol and the brain

Ethanol-;the compound found in alcoholic beverages-;interferes with the normal functioning of a long list of biological molecules, but how each of these interactions contributes to the behavioral effects of alcohol is not fully understood.

8 Jan 2024

Engineered virus-like particles power up gene editing, correcting blindness in mice

Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals.

8 Jan 2024

Sesame protein-derived peptides show promise in fighting E. coli and S. aureus

A study in "Nutrients" reveals that sesame protein-derived peptides, Ala-Gly-Gly-Val-Pro-Arg and Ser-Thr-Ile-Arg, show effective antibacterial activity against Escherichia coli and Staphylococcus aureus.

7 Jan 2024

Unlocking the power of diet: How miRNAs influence health and disease

The role of dietary microRNAs (miRNAs) in health and disease.

5 Jan 2024

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Researchers developed an RNA-based switch, the pA regulator system, to control gene expression in mammalian cells by modulating synthetic polyA signal cleavage, offering a novel approach for gene therapy applications.

4 Jan 2024

Gut microbes revealed as key players in liver disease solutions

In the editorial published on 4 September 2023, in the "gut-liver axis" special issue of the journal Hepatobiliary & Pancreatic Diseases International, Dr. Jian-Gao Fan and Dr. Lu Jiang from Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine provided a comprehensive elucidation of the pivotal role of gut microbiota in various liver diseases.

4 Jan 2024

Study finds previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease

Researchers explored the effects of a small humanin-like peptide 2 (SHLP2) variant on mitochondrial function.

4 Jan 2024

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Recent studies by Zampaloni et al. and Pahil et al. published in the journal Nature describe a novel method of inhibiting the growth of Gram-negative bacteria such as Acinetobacter using antibiotics consisting of macrocyclic peptides that target the bacterial protein bridge machinery that transports lipopolysaccharides from the cytoplasm to the outer membrane.

4 Jan 2024

New approach leverages macrophages to treat traumatic brain injury

Scientists have created a new treatment for traumatic brain injury (TBI) that shrank brain lesions by 56% and significantly reduced local inflammation levels in pigs.

3 Jan 2024

New brain imaging technique sheds light on invisible mTBIs

Researchers have created a new brain imaging method that allows mild traumatic brain injuries (mTBIs) to be diagnosed, even when existing imaging techniques like magnetic resonance imaging (MRI) don't show any structural abnormalities.

3 Jan 2024

Unlocking the appetite-stimulating secrets of cannabis through rodent brain studies

Study reveals that cannabinoid-1 receptor-expressing neurons in the mediobasal hypothalamus play a key role in the appetite-stimulating effects of inhaled cannabis in rodents, offering insights into potential treatments for anorexia.

2 Jan 2024

Novel PET tracer accurately detects common cancer mutation for tailored treatment

A novel PET imaging tracer has been proven to safely and effectively detect a common cancer gene mutation that is an important molecular marker for tumor-targeted therapy.

2 Jan 2024

Scientists take a major step towards realizing synthetic CO2 fixing pathways in living cells

Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2).

2 Jan 2024

Targeted ocular spectroscopy shines new light on retinal health

Study demonstrates the effectiveness of targeted ocular fluorescence spectroscopy for analyzing the eye fundus, offering potential advancements in diagnosing and treating eye diseases.

1 Jan 2024

Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

This study is led by Dr. Shuyang Yu (College of Biological Sciences, China Agricultural University), Dr. Jingyu Xu (The Collaborative Innovation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University) and Dr. Xuguang Du (College of Biological Sciences, China Agricultural University) and illustrated the key role of Mettl3 in CD8 T cell response during acute infection model.

29 Dec 2023

GFH009 disrupts growth signals and triggers apoptosis in hematologic malignancies

A new research paper was published in Oncotarget's Volume 14 on December 20, 2023, entitled, "The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies."

28 Dec 2023

in vivo News and Research

Amino acid nanoparticles show promise for cancer treatment

Scripps scientists debunk long-held theory about alcohol and the brain

Engineered virus-like particles power up gene editing, correcting blindness in mice

Sesame protein-derived peptides show promise in fighting E. coli and S. aureus

Unlocking the power of diet: How miRNAs influence health and disease

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Gut microbes revealed as key players in liver disease solutions

Study finds previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

New approach leverages macrophages to treat traumatic brain injury

New brain imaging technique sheds light on invisible mTBIs

Unlocking the appetite-stimulating secrets of cannabis through rodent brain studies

Novel PET tracer accurately detects common cancer mutation for tailored treatment

Scientists take a major step towards realizing synthetic CO2 fixing pathways in living cells

Targeted ocular spectroscopy shines new light on retinal health

Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

GFH009 disrupts growth signals and triggers apoptosis in hematologic malignancies

Common inflammation pathway turns anthrax toxin into killer

New family of polymers can kill bacteria without inducing antibiotic resistance

Monkey stem cells made easy: New method unveils xeno-free, efficient culture system

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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