microRNA News and Research

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In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression.
Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Tracking down microRNA candidates linked to disease

Tracking down microRNA candidates linked to disease

Study finds evidence of lasting effects from head injuries at younger age than expected

Study finds evidence of lasting effects from head injuries at younger age than expected

Study pinpoints new marker that can predict Crohn’s disease subtype

Study pinpoints new marker that can predict Crohn’s disease subtype

Nanopore technology combined with DNA computing to catch early biomarkers for small cell lung cancer

Nanopore technology combined with DNA computing to catch early biomarkers for small cell lung cancer

Krembil scientists develop potential treatment to stop knee and spine osteoarthritis

Krembil scientists develop potential treatment to stop knee and spine osteoarthritis

Urine exRNA may be source of biomarkers for muscular dystrophy

Urine exRNA may be source of biomarkers for muscular dystrophy

Key signaling molecule that helps stem cells make healthy bone declines as we age

Key signaling molecule that helps stem cells make healthy bone declines as we age

Researchers find new way to differentiate between active and inactive viruses

Researchers find new way to differentiate between active and inactive viruses

Researchers discover mechanism that steers growth of cancer cells in melanoma and liver cancer

Researchers discover mechanism that steers growth of cancer cells in melanoma and liver cancer

Delivering miRNAs to treat patients with inflammatory bowel disease

Delivering miRNAs to treat patients with inflammatory bowel disease

Researchers deliver microRNAs to treat patients with inflammatory bowel disorder

Researchers deliver microRNAs to treat patients with inflammatory bowel disorder

Study reveals how gene variant affects chronic pain outcomes after trauma

Study reveals how gene variant affects chronic pain outcomes after trauma

Inhibition of miR-24-3p may serve as potential treatment target for mesothelioma

Inhibition of miR-24-3p may serve as potential treatment target for mesothelioma

Protein aggregation in neurons linked to gene regulation in Huntington's disease

Protein aggregation in neurons linked to gene regulation in Huntington's disease

Researchers focus on uncoupling obesity from diabetes

Researchers focus on uncoupling obesity from diabetes

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Study of neuroprotective microRNAs may lead to new avenues for treating tauopathies

Study of neuroprotective microRNAs may lead to new avenues for treating tauopathies

Researchers study how herpesviruses contribute to increased oral inflammation

Researchers study how herpesviruses contribute to increased oral inflammation

Researchers uncover new mechanisms underlying common kidney cancer in children

Researchers uncover new mechanisms underlying common kidney cancer in children