microRNA News and Research

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In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression.
Horizon Discovery and Pharmahungary report positive early-stage results for novel micro-RNA therapeutic for ischemic heart diseases

Horizon Discovery and Pharmahungary report positive early-stage results for novel micro-RNA therapeutic for ischemic heart diseases

Crumpled graphene can be used to make ultra-sensitive cancer DNA detector

Crumpled graphene can be used to make ultra-sensitive cancer DNA detector

Crumpled grapheme can be more sensitive in detecting DNA cancer markers

Crumpled grapheme can be more sensitive in detecting DNA cancer markers

Scientists find new way to amplify miRNA in live tumor cells for bioimaging

Scientists find new way to amplify miRNA in live tumor cells for bioimaging

Overview of prognostic and predictive factors in pancreatic cancer

Overview of prognostic and predictive factors in pancreatic cancer

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Both strands of microRNA cooperate to drive cancer growth and aggressiveness, research shows

Both strands of microRNA cooperate to drive cancer growth and aggressiveness, research shows

Treating soft tissue sarcoma with shorter radiation treatment found to be safe, effective

Treating soft tissue sarcoma with shorter radiation treatment found to be safe, effective

P53-deficient oral cancers recruit and reprogram nerves to fuel tumor growth

P53-deficient oral cancers recruit and reprogram nerves to fuel tumor growth

MGH researchers uncover potential antiviral drug target for treating infectious diseases

MGH researchers uncover potential antiviral drug target for treating infectious diseases

Persistent TB infection of macrophages puts the brakes on immune engines, study shows

Persistent TB infection of macrophages puts the brakes on immune engines, study shows

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

A fast, sensitive technique to detect cancer markers brings liquid biopsy closer to clinic

A fast, sensitive technique to detect cancer markers brings liquid biopsy closer to clinic

Detection of mouth, throat cancer through saliva testing could become reality

Detection of mouth, throat cancer through saliva testing could become reality

Gut disease and gene analysis networks

Gut disease and gene analysis networks

$1 million international study aims to mend a broken heart

$1 million international study aims to mend a broken heart

Study may provide novel therapeutic approach for Huntington's, Parkinson's diseases

Study may provide novel therapeutic approach for Huntington's, Parkinson's diseases

Study reveals novel pathway to target colorectal cancer

Study reveals novel pathway to target colorectal cancer