microRNA News and Research

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In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression.
HDO-antimiR could be a potent weapon to combat microRNA-related disease

HDO-antimiR could be a potent weapon to combat microRNA-related disease

'Junk' DNA mutations highly significant in autism and stroke

'Junk' DNA mutations highly significant in autism and stroke

Fat cells may be egging on melanoma cells to become more aggressive

Fat cells may be egging on melanoma cells to become more aggressive

Extracellular vesical microRNAs from fat cells can disrupt disposal of cholesterol

Extracellular vesical microRNAs from fat cells can disrupt disposal of cholesterol

Novel insight into microRNA function can be crucial for the development of gene therapy

Novel insight into microRNA function can be crucial for the development of gene therapy

New biomarker in urine can help detect aggressive prostate cancer

New biomarker in urine can help detect aggressive prostate cancer

Study solves mysteries of complex microRNA oncogenes

Study solves mysteries of complex microRNA oncogenes

Suppressing amygdala molecule enables faster recovery from PTSD symptoms

Suppressing amygdala molecule enables faster recovery from PTSD symptoms

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

Investigating RNA-based regulation of the cardiovascular system

Investigating RNA-based regulation of the cardiovascular system

New blood-based biomarker can detect Alzheimer's in its earliest stages

New blood-based biomarker can detect Alzheimer's in its earliest stages

Cutting the test time for disease biomarkers using extracellular vesicles

Cutting the test time for disease biomarkers using extracellular vesicles

Study helps explain why lack of sleep is bad for the heart

Study helps explain why lack of sleep is bad for the heart

'Fingerprint' associated with a person's sleep habits may serve as warning sign for heart disease

'Fingerprint' associated with a person's sleep habits may serve as warning sign for heart disease

UVA researchers identify how cancers subvert wound healing process to grow and spread

UVA researchers identify how cancers subvert wound healing process to grow and spread

Cannabis, Alcohol and the Epigenome

Cannabis, Alcohol and the Epigenome

Discovery of biomarkers could lead to new, better treatment options for heart disease

Discovery of biomarkers could lead to new, better treatment options for heart disease

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

VCU researchers home in on microRNA processing for new cancer therapies

VCU researchers home in on microRNA processing for new cancer therapies

Researchers uncover mechanism that initiates sexual organs maturation

Researchers uncover mechanism that initiates sexual organs maturation