siRNA News and Research

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Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 nucleotides in length, that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shaping the chromatin structure of a genome; the complexity of these pathways is only now being elucidated.
New potential avenues to predict and prevent ovarian cancer metastasis

New potential avenues to predict and prevent ovarian cancer metastasis

NCL collaborates with PeptiMed to evaluate safety and efficacy of nanocomplex materials

NCL collaborates with PeptiMed to evaluate safety and efficacy of nanocomplex materials

Research to identify new potential targets for cancer therapy

Research to identify new potential targets for cancer therapy

EU-funded project aims to identify potential new targets for cancer therapy

EU-funded project aims to identify potential new targets for cancer therapy

Alnylam announces new pre-clinical results with DC for ALN-CC5 to treat complement-mediated diseases

Alnylam announces new pre-clinical results with DC for ALN-CC5 to treat complement-mediated diseases

Co-founder of Avidity Nanomedicines to receive 2014 Prince of Asturias Award

Co-founder of Avidity Nanomedicines to receive 2014 Prince of Asturias Award

Findings may help medical researchers identify effective drug targets for triple negative breast cancer

Findings may help medical researchers identify effective drug targets for triple negative breast cancer

Study: RNAi silencing strategy blocks production of mutant huntingtin protein

Study: RNAi silencing strategy blocks production of mutant huntingtin protein

DNA-directed RNA interference and hepatitis C: an interview with Carl Stubbings, Chief Business Officer, Benitec Biopharma

DNA-directed RNA interference and hepatitis C: an interview with Carl Stubbings, Chief Business Officer, Benitec Biopharma

Researchers create tiny, biodegradable nanoparticles that carry DNA to brain cancer cells

Researchers create tiny, biodegradable nanoparticles that carry DNA to brain cancer cells

Scientists discover protein potentially good target for influenza A virus

Scientists discover protein potentially good target for influenza A virus

Scientists unlock one of mysteries of modern genetics

Scientists unlock one of mysteries of modern genetics

Arrowhead receives approval to initiate Phase 2a clinical trial of ARC-520 for chronic HBV infection

Arrowhead receives approval to initiate Phase 2a clinical trial of ARC-520 for chronic HBV infection

RNA interference approach holds great promise for treating cancer and other diseases

RNA interference approach holds great promise for treating cancer and other diseases

Red wine and dark chocolate taste great and have heart-healthy components

Red wine and dark chocolate taste great and have heart-healthy components

Splicing findings offer lung cancer clues

Splicing findings offer lung cancer clues

Researchers identify therapeutic target for cervix cancer

Researchers identify therapeutic target for cervix cancer

Chinese and American researchers introduce new approach to gene therapy

Chinese and American researchers introduce new approach to gene therapy

Breakthrough technology could provide new approach for treatment of chronic wounds

Breakthrough technology could provide new approach for treatment of chronic wounds

Horizon, AstraZeneca partner to explore oncology-relevant genotypes to identify novel drug targets

Horizon, AstraZeneca partner to explore oncology-relevant genotypes to identify novel drug targets