The CARDIOsmart ultrafiltration device used in a cardiac disease of extensive epidemiological impact, and is indeed the most common cause of hospitalization. The CARDIOsmart provides a solution to patient fluid overload, and noticeably reduces the incidence of re-admission. It provides an adjunct therapy to diuretic treatment and also can be used in patients resistant to diuretics. It is also recommended for use during the early stage of the disease. This Ultrafiltration technique is used also during Cardiopulmonary by-pass, in the reheating phase to remove water accumulation (conventional ultrafiltration), by spontaneous filtration using a hemofilter.