CellDrop Automated Cell Counters allow users to Count Cells Without Slides™.
DirectPipette™ Technology eliminates plastic slides and cumbersome hemocytometers from routine cell counting by adding a simple Load, Count and Wipe Clean workflow.
Featuring dual fluorescence and brightfield optics, variable height sample chamber and powerful, easy-to-use analysis software, the CellDrop enables the fastest cell counts, viability assessment and GFP transfection efficiency measurements across the widest range of cell density, cell type and application.
The CellDrop Series brings the familiar Load, Measure & Wipe Clean functionality of microvolume spectrophotometers to cell counting. Traditional plastic slides or glass hemocytometers are replaced by two permanent optical sapphire surfaces.
These are positioned parallel to one another by a calibration-free, high-precision mechanism, forming a chamber of precisely defined height. 10 µL of cell suspension is pipetted into the chamber, analyzed and simply wiped away with a dry laboratory wipe. The powerful live-view image allows instant verification that cleaning has been successful.
Image credit: DeNovix
Accurate across the widest range of cell size and density
Using conventional counting methods, samples with high or low cell densities require time consuming dilution or concentration steps. The variable height chamber of the CellDrop adjusts chamber depth automatically, delivering the most accurate counts over the widest cell densities – 7.0 x 10e2 to 2.5 x 10e7 cells/mL. Chamber height can also be adjusted to accommodate almost any cell with a diameter range of 4 to 400 µm.
Designed by life scientists, the CellDrop EasyApps® Software exceeds the functionality of high cost cell counters while delivering the ease of use of simpler systems. EasyApps combines with a high definition, 7″ touchscreen interface to give error-free operation with sample loading to data exporting in seconds.
Pre-installed with a range of common applications for one-touch analysis of assays for cell counting such as Brightfield, Trypan blue, AO/PI, GFP and Yeast and the ability to create custom methods makes the CellDrop a flexible workhorse for the busy, multi-user lab.
Cell Size Histograms allow easy gating for non-target cells or cell debris. Simply drag the slider to set the cell size of interest. Image credit: DeNovix
High Definition cell outlining and declustering algorithms developed by DeNovix provide high accuracy cell counts of regular and irregular cells even at high density. Image credit: DeNovix
Viability measurements of PBMCs in the presence of debris and red blood cells. The unique combination of flexible hardware and custom software ensures compatibility with a broad range of cells and assays. Image credit: DeNovix
Automatically calculate cells / ml and % viability along with a range of useful cell metrics. Add dilution calculations to your protocols to calculate volumes of cells and buffer required to meet target cell densities. Image credit: DeNovix
Flexible reporting options allow easy exporting in a format to suit each lab member. Email results, print to a network printer, save to a network drive or USB. Data is also saved to a large in-built hard drive for extra data security. Image credit: DeNovix
The small footprint and onboard processing of CellDrop allow it to fit inside most flow hoods where required. For applications that require the cells to be contained when reading, all instruments also have the ability to read samples in common disposable plastic slides and reusable slides without the need for additional adaptors.
Image credit: DeNovix
Available in Dual Fluorescence and Brightfield (CellDrop FL) or Brightfield only (CellDrop BF) models.
DeNovix CellDrop™ Cell Counters - Count Cells Without Slides
Video Credit: DeNovix
21 CFR Part 11 compliance ready
The EasyApps Secure software offers an optional range of software controls that enable regulated GxP facilities to effortlessly combine CellDrop into their cell counting workflow. The software is completely built-in inside the on-board operating system and comprises an array of features crucial to ensuring compliance, such as the following:
- Built-in electronic signature controls
- Password-protected access to the system
- Sophisticated data handling and export tools
- Secure audit trail recording
- All-inclusive user account management