CellDrop™ Cell Counters from DeNovix

CellDrop Cell Counters feature unique DirectPipette™ Technology to eliminate plastic slides and cumbersome hemocytometers from routine cell counting. Featuring dual fluorescence and brightfield optics, variable height sample chamber, and powerful, easy-to-use analysis software, the CellDrop enables the fastest cell counts, viability assessment, and GFP transfection efficiency measurements across the widest range of cell density, cell type and application.

DirectPipette™ Technology

The CellDrop Series brings the familiar Load, Measure & Wipe Clean functionality of microvolume spectrophotometers to cell counting. Traditional plastic slides or glass hemocytometers are replaced by two permanent optical sapphire surfaces. These are positioned parallel to one another by a calibration-free, high-precision mechanism, forming a chamber of precisely defined height. 10µL of cell suspension is pipetted into the chamber, analyzed and simply wiped away with a dry laboratory wipe. The powerful live-view image allows instant verification that cleaning has been successful.

Accurate Across the Widest Range of Cell Size and Density

Using conventional counting methods, samples with high or low cell densities require time consuming dilution or concentration steps. The variable height chamber of the CellDrop adjusts chamber depth automatically, delivering the most accurate counts over the widest cell densities – 7 x 102 to 4 x 107. Chamber height can also be adjusted to accommodate almost any cell with a diameter range of 4 to 400µm.

Easy-to-Learn, Powerful-to-Use

Designed by life scientists, the CellDrop EasyApps® Software exceeds the functionality of high cost cell counters while delivering the ease of use of simpler systems. EasyApps combines with a high definition, 7″ touchscreen interface to give error-free operation with sample loading to data exporting in seconds. Pre-installed with a range of common applications for one-touch analysis of assays such as Brightfield, Trypan blue, AO/PI, GFP and Yeast and the ability to create custom methods makes the CellDrop a flexible workhorse for the busy, multi-user lab.

Cell Gating

Cell Size Histograms allow easy gating for non-target cells or cell debris. Simply drag the slider to set the cell size of interest.

Cell Size Histograms allow easy gating for non-target cells or cell debris. Simply drag the slider to set the cell size of interest.

Declustering

High Definition cell outlining and declustering algorithms developed by DeNovix provide high accuracy cell counts of regular and irregular cells even at high density.

High Definition cell outlining and declustering algorithms developed by DeNovix provide high accuracy cell counts of regular and irregular cells even at high density.

Primary Cells

Viability measurements of PBMCs in the presence of debris and red blood cells. The unique combination of flexible hardware and custom software ensures compatibility with a broad range of cells and assays.

Viability measurements of PBMCs in the presence of debris and red blood cells. The unique combination of flexible hardware and custom software ensures compatibility with a broad range of cells and assays.

Results

Automatically calculate cells / ml and % viability along with a range of useful cell metrics. Add dilution calculations to your protocols to calculate volumes of cells and buffer required to meet target cell densities.

Automatically calculate cells / ml and % viability along with a range of useful cell metrics. Add dilution calculations to your protocols to calculate volumes of cells and buffer required to meet target cell densities.

Exporting

Flexible reporting options allow easy exporting in a format to suit each lab member. Email results, print to a network printer, save to a network drive or USB. Data is also saved to a large in-built hard drive for extra data security.

Flexible reporting options allow easy exporting in a format to suit each lab member. Email results, print to a network printer, save to a network drive or USB. Data is also saved to a large in-built hard drive for extra data security.

Hazardous Samples?

The small footprint and onboard processing of CellDrop allow it to fit inside most flow hoods where required. For applications that require the cells to be contained when reading, all instruments also have the ability to read samples in common disposable plastic slides and reusable slides without the need for additional adaptors.

Models

Available in Dual Fluorescence and Brightfield (CellDrop FL) or Brightfield only (CellDrop BF) models.

Video Link: https://www.denovix.com/wp-content/uploads/2019/01/05V-Fine_Cut-TS-DeNovix_CellDrop-V24.mp4