SCIEX ZenoTOF 7600 mass spectrometry system

The SCIEX ZenoTOF 7600 system unites enhanced MS/MS sensitivity, strong fragmentation performance, and advanced data-independent acquisition capabilities to help researchers uncover deeper biological findings. Using the Zeno trap and electron-activated dissociation, the platform enables sensitive detection and detailed structural characterization for proteomics, lipidomics, metabolomics, and biopharmaceutical workflows.

The ZenoTOF 7600 system helps users:

  • Identify low-abundance molecules that may be overlooked by traditional QTOF systems
  • Confidently identify post-translational modifications
  • Distinguish compounds that are structurally similar, including positional isomers
  • Characterize proteins, peptides, lipids, and metabolites with high sensitivity
  • Produce rich MS/MS data for qualitative and quantitative analysis
  • Improve identification and quantitation using Zeno SWATH DIA

Key innovations

  • Zeno trap technology: Efficiently captures and releases ions to strengthen MS/MS sensitivity across a range of applications
  • Zeno SWATH DIA: Merges broad DIA coverage with Zeno trap sensitivity to support deeper coverage and better quantitative performance
  • Electron-activated dissociation: Uses adjustable, electron-based fragmentation to preserve important structural information

Ideal applications

  • Discovery proteomics
  • Biomarker discovery
  • Biopharmaceutical characterization
  • Metabolomics and lipidomics
  • Targeted accurate-mass quantitation
  • Small-molecule structural elucidation

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