CRISPR

In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.
CRISPR: Ethical and Safety Concerns

CRISPR and Cas proteins have become a crucial tool for genetic manipulation in biomedical research and biotechnology, and the crux of its action is the recognition of specific sequences in the DNA and their subsequent cleavage from the chain. One specific system, CRISPR-Cas9, has become the standard for genetic editing, since it can be tailored to target any set of DNA sequences. Thus it is of no wonder that it caused an upheaval in biomedical field.

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Overview

Feature Articles

Latest CRISPR News and Research

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Gene-edited tomatoes could be a simple solution to address vitamin D insufficiency

Gene-edited tomatoes could be a simple solution to address vitamin D insufficiency

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Potential therapeutic target discovered for pancreatic ductal adenocarcinoma tumors

Potential therapeutic target discovered for pancreatic ductal adenocarcinoma tumors

Micro Products with Macro Impact; The Role of Microplate Readers in Life Sciences

Micro Products with Macro Impact; The Role of Microplate Readers in Life Sciences

Emerging DNA-based sensors are promising tools for food safety

Emerging DNA-based sensors are promising tools for food safety

Why do diabetic patients have more severe SARS-CoV-2 infections?

Why do diabetic patients have more severe SARS-CoV-2 infections?

Researchers discover new gene that confers resistance to prostate cancer treatment

Researchers discover new gene that confers resistance to prostate cancer treatment

The promise of RNA medicine is targeted and personalized

The promise of RNA medicine is targeted and personalized

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

bit.bio launches Huntington’s disease human cell model

bit.bio launches Huntington’s disease human cell model

Novel drug target may help overcome resistance to EZH2 inhibitors in SMARCB1 mutated cancers

Novel drug target may help overcome resistance to EZH2 inhibitors in SMARCB1 mutated cancers

Evaluating the Role of Automated LabTech Instruments within Research

Evaluating the Role of Automated LabTech Instruments within Research

Potential antiviral targets in SARS-CoV-2

Potential antiviral targets in SARS-CoV-2

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

Study explores SARS-CoV-2 RNA genome's functional interactions with host cell

Study explores SARS-CoV-2 RNA genome's functional interactions with host cell

New method increases efficiency of gene editing while minimizing DNA deletion sizes

New method increases efficiency of gene editing while minimizing DNA deletion sizes

Unraveling how strigoractone hormone regulates massive gene networks controlling plant growth

Unraveling how strigoractone hormone regulates massive gene networks controlling plant growth

Study offers critical clues into longstanding mystery of deep sleep

Study offers critical clues into longstanding mystery of deep sleep

Genetic cause of lupus identified

Genetic cause of lupus identified