CRISPR

In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

CRISPR-Based Diagnostics: The Future of Disease Detection

CRISPR-based diagnostics offer transformative solutions for disease detection, utilizing advanced gene-editing tools for precise and rapid molecular testing.

CRISPR-Cas14: Discovery, Function, Advantages

What is CRISPR/Cas9?

How Does CRISPR Compare to Other Gene-Editing Techniques?

CRISPR: Ethical and Safety Concerns

CRISPR-Cpf1

Could CRISPR Repair CFTR in Cystic Fibrosis Patients?

Electroporation and the Production of Knockout Mice

Manipulating RNA sequences using CRISPR-Cas13

CRISPR: The End for Zinc Fingers?

Editing Sperm DNA using CRISPR

Understanding CRISPR Therapy

See more featured articles »

Uses of CRISPR/Cas Biosensing Systems

CRISPR Interference (CRISPRi) for Gene Suppression

Unlocking the Potential: CRISPR-Cas9 Gene Editing in Liver Diseases

CPISPR Applications

Latest CRISPR News and Research

Study reveals how p53 mutations cause tumors to resist cancer immunotherapy

Immune checkpoint blockade (ICB) therapy has transformed cancer treatment, but many tumors remain resistant.

22 Jul 2026

Study reveals sex-based protein differences across lung cancer types

Biological sex factors into cancer in ways you might not expect. In lung cancer, a form called squamous cell carcinoma disproportionately affects males while adenocarcinoma occurs more frequently in females.

21 Jul 2026

UC San Diego and IGI join hands to develop advanced genome-editing tools and applications

The University of California San Diego and the Innovative Genomics Institute (IGI), founded by Nobel laureate and CRISPR gene editing co-discoverer Jennifer Doudna, announced a new partnership today to jointly develop cutting-edge genomic tools for addressing large-scale challenges in health and the environment.

21 Jul 2026

Researchers use canine iPSCs to generate red blood cell-like cells

Blood transfusions are crucial in human and veterinary medicine, yet human blood reserves are in constant need of donors while blood bank systems in veterinary care are nearly non-existent.

19 Jul 2026

New portable strip test accurately detects mosquito-borne viruses

A research team has developed a multisite bridging-mediated lateral flow immunoassay (mbLFIA) that enables highly sensitive, portable detection of mosquito-borne viruses, using Chikungunya virus (CHIKV) as a model target.

17 Jul 2026

Researchers uncover new T cell attack mechanism against acute myeloid leukemia

Researchers at The University of Texas MD Anderson Cancer Center have discovered a new way in which T cells attack acute myeloid leukemia (AML) cells, which may help explain why AML is particularly sensitive to immune-based treatments and could guide the development of future cancer immunotherapies.

15 Jul 2026

New project targets recurrent urinary tract infections using phages

Researchers at the HUN-REN Biological Research Centre, Szeged are participating in a €15 million Horizon Europe program that will investigate the combination of phage therapy and microbiome restoration in a European clinical trial.

14 Jul 2026

New genetic reference map accelerates human stem cell research

A team led by bioengineers at the University of California San Diego has developed a genome-scale reference map that details how individual genes control the functions and identities of human stem cells.

13 Jul 2026

Stem cell study uncovers molecular pathway for enamel regeneration

Tooth enamel is the hardest substance in the human body, yet once damaged, it cannot regenerate naturally.

9 Jul 2026

New genetic screening method unlocks insights into human development

A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides new insights into human development.

9 Jul 2026

Biohub researchers use artificial intelligence to uncover new psoriasis targets

Biohub researchers performed what they believe is the first genome-wide CRISPR study of primary human adult skin cells, then used an AI model to mine the results for overlooked drug targets for psoriasis.

8 Jul 2026

Toronto researchers uncover genetic drivers of triple negative breast cancer

Researchers have solved a long-standing mystery of how abnormal chromosomes drive cancer, identifying 81 new genes involved in aggressive breast cancer.

8 Jul 2026

New genome editing tool unlocks fungi's hidden drug-producing potential

Researchers have spent decades-and billions of dollars-sequencing animal and crop genomes, but fungi have historically been the forgotten middle child of genomics, only noticed when they're ruining bread or colonizing toes.

2 Jul 2026

New framework redefines phage therapy for combating antimicrobial resistance

A new perspective article in Biocontaminant proposes a three-part evolutionary framework for using bacteriophages to better control antimicrobial resistance.

2 Jul 2026

LEF1 and niche-derived factors regulate T cell stemness across chronic diseases

T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged campaign against a chronic condition - like a viral infection, or cancer - the body needs a steady supply of these killer troops.

1 Jul 2026

Researchers develop new model to study aggressive melanomas

Researchers have created a powerful new cellular model to study rare tumors that are resistant to immunotherapies.

29 Jun 2026

Pioneering gene therapy for rare immune disorder shows promise in early pre-clinical studies

The development of a pioneering gene therapy to treat a devastating, rare immune disorder led by UCL scientists is set to move into its next phase following promising early pre-clinical studies.

27 Jun 2026

Base editing technique reveals crucial gene for early human development

Research led by the University of Cambridge Loke Centre for Trophoblast Research has shown that a genome editing technique can be used to alter a single gene in human embryonic cells, enabling the study of very early human development in unparalleled detail.

25 Jun 2026

European project receives €15 million to study phage-based therapies

Bacteria are becoming increasingly resistant to antibiotics. One alternative is treatment with viruses that exclusively infect bacteria, known as phages.

25 Jun 2026

Using the mathematics of quantum mechanics to improve neuroblastoma outcomes

For a child diagnosed with neuroblastoma-the most common infant cancer, occurring when early nerve cells grow out of control-the path to treatment isn't simple.

22 Jun 2026