CRISPR

In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

CRISPR-Based Diagnostics: The Future of Disease Detection

CRISPR-based diagnostics offer transformative solutions for disease detection, utilizing advanced gene-editing tools for precise and rapid molecular testing.

CRISPR: The End for Zinc Fingers?

CRISPR: Ethical and Safety Concerns

Could CRISPR Repair CFTR in Cystic Fibrosis Patients?

CPISPR Applications

CRISPR-Cas14: Discovery, Function, Advantages

What is CRISPR/Cas9?

Electroporation and the Production of Knockout Mice

How Does CRISPR Compare to Other Gene-Editing Techniques?

Uses of CRISPR/Cas Biosensing Systems

Manipulating RNA sequences using CRISPR-Cas13

CRISPR-Cpf1

See more featured articles »

CRISPR Interference (CRISPRi) for Gene Suppression

Understanding CRISPR Therapy

Unlocking the Potential: CRISPR-Cas9 Gene Editing in Liver Diseases

Editing Sperm DNA using CRISPR

Latest CRISPR News and Research

Advances in X chromosome inactivation open therapeutic opportunities for X-linked genetic disorders

A new review explores how advances in understanding X chromosome inactivation (XCI) are creating potential therapeutic opportunities for a range of X-linked genetic disorders, including Rett syndrome, Fabry disease, Duchenne muscular dystrophy, hemophilia, and others.

3 Aug 2026

New OpenABE gene editor improves editing efficiency by up to 36 times

A joint research team led by Professor Daesik Kim (Department of Medicine, Sungkyunkwan University), along with Professor Yong-Sub Kim (University of Ulsan College of Medicine) and Professor Jae-Hyun Park (Sungkyunkwan University School of Medicine), has announced the development of 'OpenABE' (Open Adenine Base Editor).

30 Jul 2026

Study links dietary fructose to aggressive spread of ovarian cancer

A new study from The Wistar Institute has uncovered an unexpected link between fructose - a common dietary sugar - and the spread of an aggressive form of ovarian cancer.

30 Jul 2026

NIH funds mosquito genetics research to curb deadly disease spread

Mosquito-borne pathogens, including zika, yellow fever and other illnesses have serious and worldwide impacts on human health.

29 Jul 2026

Small changes in one heart protein cause distinct cardiomyopathies

Cardiomyopathies are a group of mostly hereditary, rare heart diseases in which the structure of the heart muscle tissue is impaired.

29 Jul 2026

New gene editing tool reduces Huntington's symptoms in mice

A gene editing tool designed to precisely rewrite the gene that causes Huntington's disease reduced toxic protein fragments and symptoms associated with the disease in mice, researchers at the University of Illinois Urbana-Champaign report.

29 Jul 2026

CRISPR directs layered immune response against invading bacteriophages

The main function of CRISPR-Cas systems, the revolutionary tool scientists now employ to edit genes, is to defend bacteria against threats such as viruses called bacteriophages.

24 Jul 2026

Scientists discover master molecular switch for ginseng saponin production

Sanchi ginseng (Panax notoginseng) is a cornerstone of traditional Chinese medicine, prized for its saponins-bioactive compounds with anti-inflammatory, cardiovascular, and anticancer properties.

24 Jul 2026

Emerging non-endocytic transmembrane delivery strategies for precision medicine

Conventional endocytosis-mediated delivery is limited by poor endosomal escape efficiency, making intracellular delivery of therapeutic biomacromolecules a long-standing challenge in modern biomedical research.

24 Jul 2026

CRISPR-Cas orchestrates a layered defense network to fight bacterial viruses

All cellular life-from humans to bacteria-possesses two layers of immunity: innate and adaptive. Scientists have long understood how these two types of immunity work together in higher organisms but not in the microbial world.

23 Jul 2026

AI-powered analytics and experimental validation: Transforming target identification in drug discovery

Discover how AI-powered analytics and experimental validation combine to improve target identification and accelerate drug discovery success.

From Axxam S.p.A 23 Jul 2026

DNA enhancer hubs control cancer genes in prostate tumors

Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated.

22 Jul 2026

Study reveals how p53 mutations cause tumors to resist cancer immunotherapy

Immune checkpoint blockade (ICB) therapy has transformed cancer treatment, but many tumors remain resistant.

22 Jul 2026

Study reveals sex-based protein differences across lung cancer types

Biological sex factors into cancer in ways you might not expect. In lung cancer, a form called squamous cell carcinoma disproportionately affects males while adenocarcinoma occurs more frequently in females.

21 Jul 2026

UC San Diego and IGI join hands to develop advanced genome-editing tools and applications

The University of California San Diego and the Innovative Genomics Institute (IGI), founded by Nobel laureate and CRISPR gene editing co-discoverer Jennifer Doudna, announced a new partnership today to jointly develop cutting-edge genomic tools for addressing large-scale challenges in health and the environment.

21 Jul 2026

Researchers use canine iPSCs to generate red blood cell-like cells

Blood transfusions are crucial in human and veterinary medicine, yet human blood reserves are in constant need of donors while blood bank systems in veterinary care are nearly non-existent.

19 Jul 2026

New portable strip test accurately detects mosquito-borne viruses

A research team has developed a multisite bridging-mediated lateral flow immunoassay (mbLFIA) that enables highly sensitive, portable detection of mosquito-borne viruses, using Chikungunya virus (CHIKV) as a model target.

17 Jul 2026

Researchers uncover new T cell attack mechanism against acute myeloid leukemia

Researchers at The University of Texas MD Anderson Cancer Center have discovered a new way in which T cells attack acute myeloid leukemia (AML) cells, which may help explain why AML is particularly sensitive to immune-based treatments and could guide the development of future cancer immunotherapies.

15 Jul 2026

New project targets recurrent urinary tract infections using phages

Researchers at the HUN-REN Biological Research Centre, Szeged are participating in a €15 million Horizon Europe program that will investigate the combination of phage therapy and microbiome restoration in a European clinical trial.

14 Jul 2026

New genetic reference map accelerates human stem cell research

A team led by bioengineers at the University of California San Diego has developed a genome-scale reference map that details how individual genes control the functions and identities of human stem cells.

13 Jul 2026