Hepatitis B

Hepatitis B is one type of hepatitis – a liver disease- caused by the hepatitis B virus (HBV). Hepatitis B spreads by contact with an infected person's blood, semen or other body fluid. An infected woman can give hepatitis B to her baby at birth.

What is Hepatitis B?

Hepatitis B is a viral infection of the liver that is spread when contact is made with blood or blood products from an infected individual.

Hepatitis B Prognosis

Closed Circular DNA and Hepatitis B Infection

Hepatitis B Structure: Capsid Flexibility and Function

Is Hepatitis Preventable?

Hepatitis B Prevention

Hepatitis B Mechanisms

Hepatitis B Immunization

Hepatitis B Treatment

Hepatitis B Symptoms

Hepatitis B Diagnosis

Hepatitis B and Hepatitis D

Latest Hepatitis B News and Research

WHO report shows measurable progress in reducing global hepatitis infections

Global efforts to combat viral hepatitis are delivering measurable progress in reducing infections and deaths, but the disease remains a major global health challenge, according to a new World Health Organization (WHO) report released today at the World Hepatitis Summit.

28 Apr 2026

Modeling the synergy of maternal screening and newborn HBV vaccination

Hepatitis B virus (HBV) infection acquired at birth or during early infancy can lead to lifelong health complications, including chronic liver disease. Despite longstanding recommendations for prenatal screening, an estimated 12% to 16% of pregnant individuals in the US are not screened for hepatitis B. This gap leaves a portion of newborns at risk for undetected exposure.

28 Apr 2026

Delaying hepatitis B birth vaccines increases infant infection risks

Delaying hepatitis B vaccination after birth increases infections among newborns and decreases their survival rates and quality of life, according to a new Cornell University study.

27 Apr 2026

Long-term study supports tenofovir alafenamide for chronic hepatitis B

Tenofovir alafenamide (TAF) has demonstrated comparable efficacy to tenofovir disoproxil fumarate (TDF), with improved renal and bone safety, in Chinese participants with chronic hepatitis B enrolled in two Phase 3 trials.

24 Apr 2026

WHO congratulates The Bahamas for eliminating mother-to-child transmission of HIV

In a landmark achievement for Caribbean public health, the World Health Organization (WHO) congratulates The Bahamas for becoming the latest Caribbean nation to be certified as having eliminated the mother-to-child transmission of HIV.

23 Apr 2026

What still drives childhood vaccine gaps in the United States

A nationwide analysis of provider-verified NIS-Child data from 2010 to 2023 found that US childhood vaccination coverage remained generally high but was consistently shaped by social and structural factors such as maternal education, income, insurance, language, and region. The study also showed that coverage of the combined seven-vaccine series rose over time, yet persistent disparities remained, especially for vaccines such as influenza, hepatitis A, and rotavirus.

19 Apr 2026

What the Health? From KFF Health News: A new CDC nominee, again

President Donald Trump this week nominated a former deputy surgeon general who has expressed support for vaccines to lead the Centers for Disease Control and Prevention.

17 Apr 2026

AGA update calls for better surveillance of hepatocellular carcinoma

A new update from the American Gastroenterological Association (AGA) urges stronger prevention efforts and better early-detection tools for hepatocellular carcinoma (HCC), the leading cause of cancer-related death in patients with cirrhosis, and the third most common cause of cancer-related death worldwide.

17 Apr 2026

Liver cancer burden rising globally amid shift to metabolic risks

Primary liver cancer continues to pose a major global health challenge, ranking as the third leading cause of cancer-related deaths worldwide.

15 Apr 2026

New blood test spots four cancers and other diseases by stripping away healthy DNA noise

MethylScan is a new low-cost cell-free DNA methylome test that removes much of the healthy blood DNA background, helping rare disease signals stand out more clearly. In more than 1,000 people, it showed strong performance for detecting four cancers, classifying liver diseases, and identifying organ-specific damage.

7 Apr 2026

Newsom picks a dogfight with Trump and RFK Jr. on public health

California Gov. Gavin Newsom has positioned himself as a national public health leader by staking out science-backed policies in contrast with the Trump administration.

9 Mar 2026

This doctor-senator who backed RFK Jr. now faces a fight for his job — and his legacy

The ambitious liver doctor would go just about anywhere in his home state to give people the hepatitis B vaccine.

6 Mar 2026

Denmark achieves historic elimination of mother-to-child HIV and syphilis transmission

The World Health Organization (WHO) has certified Denmark for the elimination of mother-to-child transmission (EMTCT) of HIV and syphilis, recognizing the country's sustained commitment to ensuring every child is born free of these infections.

27 Feb 2026

Rising vitamin K shot refusal increases newborn brain injury risk

Increasing numbers of parents are refusing vitamin K shots for their newborns, putting infants at greater risk of avoidable brain injuries, according to a preliminary systematic review released February 26, 2026, that will be presented at the American Academy of Neurology's 78th Annual Meeting taking place April 18-22, 2026, in Chicago and online.

26 Feb 2026

Harnessing AI to optimize the development of new protein manufacturing processes

Industrial yeasts are a powerhouse of protein production, used to manufacture vaccines, biopharmaceuticals, and other useful compounds.

17 Feb 2026

RFK Jr. made promises in order to become health secretary. He’s broken many of them.

One year after taking charge of the nation’s health department, Health and Human Services Secretary Robert F. Kennedy Jr. hasn’t held true to many of the promises he made while appealing to U.S. senators concerned about the longtime anti-vaccine activist’s plans for the nation’s care.

13 Feb 2026

Safety perceptions of major vaccines show significant drop over the past three years

In a winter marked by flu outbreaks, the persistence of Covid-19, and surges of measles cases across the United States, an Annenberg survey finds that a sizable majority of Americans think the three vaccines that combat these potentially deadly illnesses are safe to take, although perceptions of the safety of all three vaccines showed a statistically significant drop over the past three years.

10 Feb 2026

Global analysis reveals up to four in ten cancer cases could be prevented

Up to four in ten cancer cases worldwide could be prevented, according to a new global analysis from the World Health Organization (WHO) and its International Agency for Research on Cancer (IARC).

4 Feb 2026

Dynamic viral markers predict treatment response in hepatitis B

The rate of functional cure (HBsAg loss) remains unsatisfactory following pegylated interferon (PEG-IFN) treatment in chronic hepatitis B. To optimize PEG-IFN administration, this study aimed to evaluate virological markers to predict functional cure and/or hepatitis B e antigen (HBeAg) loss.

30 Jan 2026

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, particularly in regions with high hepatitis B virus prevalence.

24 Jan 2026