Hot-Melt Extrusion and Downstream Processing

Downstream processing is the crucial step that connects formulation development to the final pharmaceutical product.

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In this brochure, Thermo Scientific takes a closer look at how integrated hot-melt extrusion (HME) workflows, paired with flexible downstream processing technologies from Thermo Fisher Scientific, can streamline the production of solid oral dosage forms, films, implants, and even personalized medicines.

The team will walk you through key post-extrusion steps like shaping, cutting, and molding, showing how each one plays a role in fine-tuning the mechanical properties and ensuring accurate, consistent dosage forms.

You’ll also see how a modular system design makes it easier to scale from early research all the way to pilot runs and commercial production, helping teams move faster without compromising on quality or process control.

Download the brochure to explore how a smart, modular approach to downstream processing can support your HME workflows from start to finish.

This information has been sourced, reviewed and adapted from materials provided by Thermo Fisher Scientific – Production Process & Analytics.

For more information on this source, please visit Thermo Fisher Scientific – Production Process & Analytics.

Last Updated: Feb 11, 2026