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Cell division linked to oxygen levels: Johns Hopkins research

Cells grow abundant when oxygen is available, and generally stop when it is scarce. Although this seems straightforward, no direct link ever has been established between the cellular machinery that senses oxygen and that which controls cell division. Now, in the June 10 issue of Molecular Cell, researchers at Johns Hopkins report that the MCM proteins, which promote cell division, also directly control the oxygen-sensing HIF-1 protein.

12 Jun 2011

Preliminary results from Edison's EPI-A0001 28-day phase 2A trial against Friedreich's ataxia

Edison Pharmaceuticals, Inc. announced today preliminary results obtained on a 28-day phase 2A clinical trial in Friedreich's ataxia. While the primary endpoint of glucose disposition index did not show statistically significant improvement, EPI-A0001 did significantly improve neurological function as assessed by the Friedreich's Ataxia Rating Scale.

10 Jun 2011

Researchers unearth secret of immune system's success

After eight years of work, researchers have unearthed what has been a well-kept secret of our immune system's success. The findings published online on June 9th in Immunity, a Cell Press publication, offer an explanation for how specialized immune cells are able to kill infected or cancerous cells without killing themselves in the process.

From Evident Corporation - Life Sciences 10 Jun 2011

New opportunities to save another 6.4 million lives

Vaccinating children around the world against infectious diseases has saved the lives of millions over the past several decades. Now new opportunities exist to overcome remaining challenges-and save another 6.4 million lives over the current decade, according articles in the June 2011 edition of Health Affairs. The issue was produced under the journal's grant from the Bill & Melinda Gates Foundation.

10 Jun 2011

Legislation that slows human embryonic stem cell research will also harm iPS cells study

Any legislation that slows human embryonic stem cell research is likely to also seriously harm the study of induced pluripotent stem cells, according to a new study by researchers at the Stanford University School of Medicine, the Mayo Clinic and the University of Michigan.

10 Jun 2011

U-M International Center for Automotive Medicine announces new collaborative research

The University of Michigan International Center for Automotive medicine this week marked the beginning of new capabilities and new collaborative research combining trauma medicine, state-of-the-art computer analysis and automotive engineering.

10 Jun 2011

IMS Health acquires Med-Vantage

IMS Health has acquired Med-Vantage, a San Francisco-based software solutions company, to further expand its presence and capabilities in the payer marketplace. Med-Vantage offers its clients a comprehensive suite of provider performance management and member engagement solutions that promote high-quality care and address the complexities of new reimbursement and care delivery models.

10 Jun 2011

Vertex VX-770 Phase 3 STRIVE study for cystic fibrosis demonstrates improvements in lung function

Vertex Pharmaceuticals Incorporated today announced the final results from its pivotal Phase 3 STRIVE study that evaluated VX-770, a medicine in development that targets the defective protein that causes cystic fibrosis (CF).

10 Jun 2011

Premier healthcare alliance awards new agreements for ophthalmology products

The Premier healthcare alliance has announced that new agreements for ophthalmology products have been awarded.

10 Jun 2011

Turning back the clock on aging stem cells to make better bone

Researchers want to turn back the clock on aging stem cells so they'll make better bone.

10 Jun 2011

VCU Medical Center is new headquarters for Pan American Trauma Society

The Virginia Commonwealth University Medical Center is the new headquarters for the Pan American Trauma Society - the lead organization for the advancement of trauma care systems in the Americas.

10 Jun 2011

Mortality from all causes higher among hepatitis C-infected patients, study finds

Although liver-related mortality among those infected with hepatitis C is well-documented, little is known about deaths in these patients that are not related to liver problems. A new study published in Clinical Infectious Diseases and now available online sought to determine mortality from all causes, including liver- and non-liver related deaths among hepatitis C patients in the general U.S. population. The analysis found mortality from all causes to be higher in these patients.

10 Jun 2011

CDA attempts to clear confusion over vitamin D and sun exposure

The debate about vitamin D and sun exposure has been ongoing and the Canadian Dermatology Association (CDA) hopes to clear up some of the confusion.

10 Jun 2011

Hyperthermia prevents repair of tumor cells

BSD Medical Corporation, a leading provider of medical systems that utilize heat therapy to treat cancer, announced today that a study published in the Proceedings of the National Academy of Sciences demonstrated that hyperthermia can be a powerful tool to inhibit the ability of cancer cells to repair the DNA damage caused by radiation or chemotherapy.

10 Jun 2011

Free access to enteric pathogen's genetic regulation data

Just a few genes make enterohaemorrhagic E. coli (EHEC) extremely dangerous to humans. If it were not for these genes, EHEC would hardly differ from harmless enteric bacteria. Bioinformatics scientists from the Saarbr-cken Cluster of Excellence want to exploit this similarity to find starting points for effective drugs against the EHEC pathogen.

10 Jun 2011

Surgeon uses radiotracers to detect the ganglion through which tumour attempts to spread

Dr Naia Uribe-Etxebarria has shown that it is viable to detect the ganglion through which a tumour attempts to spread, using a radiotracer, in a PhD defended at the University of the Basque Country.

10 Jun 2011

MHS wins EPA's 2011 National Environmental Leadership Award in Asthma Management

Centene Corporation announced today that Managed Health Services (MHS), its Indiana subsidiary, won the 2011 National Environmental Leadership Award (Health Plan Division) in Asthma Management from the EPA (Environmental Protection Agency).

10 Jun 2011

PharmAthene to sell $6.5M of common stock and warrants in registered direct offering

PharmAthene, Inc., a biodefense company developing medical countermeasures against biological and chemical threats, announced today that it has entered into subscription agreements with certain institutional investors to sell approximately $6.5 million of its common stock and warrants in a registered direct offering.

10 Jun 2011

Viewpoints: Sebelius on medical errors; Lieberman on Medicare; The Massachusetts track record

There is no doubt that America has the world's most skilled doctors and nurses and its finest hospitals. Every day, many Americans receive care that is as good as or better than any in the world. But far too often, we fall short of that high standard when good people get trapped in flawed systems (Kathleen Sebelius and Sue Currin, 6/10).

10 Jun 2011

Research Roundup: Depression disparities; Parents' views of vaccines

Archives Of Pediatrics And Adolescent Medicine: Hospital-Based Programs For Children With Special Health Care Needs: Implications Of Health Care Reform -- This study looks at 33 hospital-based comprehensive care programs for children with special needs to evaluate their effectiveness.

10 Jun 2011

Medical News

Cell division linked to oxygen levels: Johns Hopkins research

Preliminary results from Edison's EPI-A0001 28-day phase 2A trial against Friedreich's ataxia

Researchers unearth secret of immune system's success

New opportunities to save another 6.4 million lives

Legislation that slows human embryonic stem cell research will also harm iPS cells study

U-M International Center for Automotive Medicine announces new collaborative research

IMS Health acquires Med-Vantage

Vertex VX-770 Phase 3 STRIVE study for cystic fibrosis demonstrates improvements in lung function

Premier healthcare alliance awards new agreements for ophthalmology products

Turning back the clock on aging stem cells to make better bone

VCU Medical Center is new headquarters for Pan American Trauma Society

Mortality from all causes higher among hepatitis C-infected patients, study finds

CDA attempts to clear confusion over vitamin D and sun exposure

Hyperthermia prevents repair of tumor cells

Free access to enteric pathogen's genetic regulation data

Surgeon uses radiotracers to detect the ganglion through which tumour attempts to spread

MHS wins EPA's 2011 National Environmental Leadership Award in Asthma Management

PharmAthene to sell $6.5M of common stock and warrants in registered direct offering

Viewpoints: Sebelius on medical errors; Lieberman on Medicare; The Massachusetts track record

Research Roundup: Depression disparities; Parents' views of vaccines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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