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SRI and Taiho collaborate to advance clinical development of TAS-108 breast cancer program

SRI International, an independent nonprofit research and development organization, announced today that it has assumed responsibility for further clinical development of the TAS-108 breast cancer program, in cooperation with Taiho Pharmaceuticals Co., Ltd., a leading Japanese pharmaceutical company. Further clinical development will focus on the lead compound's registration for the treatment of tamoxifen and aromatase inhibitor-resistant breast cancers.

20 Aug 2010

Palliative care recipients live longer and in less pain, study finds

The New York Times: "In a study that sheds new light on the effects of end-of-life care, doctors have found that patients with terminal lung cancer who began receiving palliative care immediately upon diagnosis not only were happier, more mobile and in less pain as the end neared — but they also lived nearly three months longer.

20 Aug 2010

Scientists discover genetic flaw that causes facioscapulohumeral muscular dystrophy

Nearly two decades after they identified the specific genetic flaw that causes a common type of muscular dystrophy, scientists believe they have figured out how that flaw brings about the disease. The finding by an international team of researchers settles a longstanding question about the roots of facioscapulohumeral muscular dystrophy or FSHD.

20 Aug 2010

Quark Pharmaceuticals announces option agreement with Novartis for QPI-1002 siRNA drug

Silence Therapeutics plc, a leading international RNAi therapeutics company, is pleased to note that its partner, Quark Pharmaceuticals, Inc., has announced the grant of an option to Novartis to obtain an exclusive worldwide license to develop and commercialise QPI-1002, a p53 temporary inhibitor siRNA drug which incorporates Silence's AtuRNAi technology.

20 Aug 2010

Moderate alcohol in family setting can prevent young people from binge drinking: Study

Italian youths whose parents allowed them to have alcohol with meals while they were growing up are less likely to develop harmful drinking patterns in the future, according to a new study led by a Boston University School of Public Health (BUSPH) researcher.

20 Aug 2010

FDA Advisory Committee votes in favor of expanding pain indications for Eli Lilly's Cymbalta

The U.S. Food and Drug Administration (FDA) Anesthetic and Life Support Drugs Advisory Committee voted 8-6 in favor of expanding the pain indications for Eli Lilly and Company's (NYSE: LLY) Cymbalta® (duloxetine HCl) to a broader pain population that will be further defined by the FDA, if approved.

20 Aug 2010

Business Group: Large employers grappling with health law changes

Reuters: As large employers take steps to comply with the health overhaul law, such as removing plans' spending limits and covering more preventive services at no cost to patients, they are also planning to shift more health care costs to workers, according to a report by the National Business Group on Health.

20 Aug 2010

Celgene receives Japan's MHLW approval for REVLIMID in deletion 5q myelodysplastic syndrome patients

Celgene International Sàrl announced that REVLIMID (lenalidomide) has been granted full marketing authorization by Japan's Ministry of Health, Labour and Welfare (MHLW) for the treatment of patients with myelodysplastic syndromes (MDS) associated with a deletion 5q cytogenic abnormality. REVLIMID was also approved in June 2010 in combination with dexamethasone, for the treatment of patients with relapsed or refractory multiple myeloma who have received at least one prior standard therapy.

20 Aug 2010

Study finds black women with SLE develop cardiovascular disease at early age

A recent study by researchers at Penn State College of Medicine found significant racial disparities in the age of systemic lupus erythematosus (SLE) patients at the time of hospital admission for cardiovascular disease (CVD) events and CVD-related death. Black women were youngest to both be admitted with CVD and to have an in-hospital death due to CVD.

20 Aug 2010

Renin test can predict appropriate drugs for BP patients: Study

Commonly prescribed drugs used to lower blood pressure can actually have the opposite effect-raising blood pressure in a statistically significant percentage of patients. A new study by researchers at Albert Einstein College of Medicine of Yeshiva University suggests that doctors could avoid this problem-and select drugs most suitable for their patients-by measuring blood levels of the enzyme renin through a blood test that is becoming more widely available. The study appears in the online edition of the American Journal of Hypertension.

20 Aug 2010

Study suggests elective surgical repair is safe intervention for abdominal aortic aneurysm

Research from the Society for Vascular Surgery in collaboration with the Mount Sinai School of Medicine Department of Health Evidence and Policy in New York City evaluated the data of 3.1 million patients who were at risk for an abdominal aortic aneurysm (AAA).

20 Aug 2010

Grand Junction, Colorado: Still the health care poster child

In this story for Kaiser Health News, Bill Scanlon reports: "Just a year ago, as opposition to the proposed health overhaul flared at town hall meetings around the country, President Barack Obama made this western Colorado town of 53,000 people a crucial stop on his tour to revive the stalled initiative" (Scanlon, 8/19).

20 Aug 2010

Muscle mass plays key role in cancer survival: Research

In the vast majority of patients with advanced cancer, their muscles will gradually waste away for reasons that have never been well understood. Now, researchers reporting in the August 20 issue of Cell, a Cell Press Publication, have found some new clues and a way to reverse that process in mice. What's more, animals with cancer that received the experimental treatment lived significantly longer, even as their tumors continued to grow.

20 Aug 2010

SIGVARIS joins Vascular Disease Foundation's National Corporate Round Table

The Vascular Disease Foundation (VDF) announced today that SIGVARIS, has become a member of VDF's National Corporate Round Table. The National Corporate Round Table serves to help the foundation in its public awareness and educational efforts.

20 Aug 2010

MUH performs first intracranial radiosurgery with Leksell Gamma Knife Perfexion system

Macquarie University Hospital (MUH) performed Australia's first Gamma Knife surgery with its new Leksell Gamma Knife Perfexion system, making it the country's first and only center capable of providing dedicated intracranial radiosurgery.

20 Aug 2010

Model explains mechanical cause of high blood pressure

In a paper published today by Brahm Brahm, a model was introduced explaining the cause of high blood pressure. This model describes how both your heart and arteries contract to pump blood, creating pressure in the process. For the first time, this contraction cycle of the muscles in artery walls has been mathematically described.

20 Aug 2010

Binge drinking increases cardiovascular disease risk: Research

If you have high blood pressure, binge drinking may dramatically raise your risk of stroke or heart-related death, according to a South Korean study reported in Stroke: Journal of the American Heart Association.

20 Aug 2010

First pathological evidence of link between repeated head injuries and chronic traumatic Encephalomyopathy

Researchers with the Department of Veterans Affairs (VA) and the Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine have provided the first pathological evidence of a link between repeated head injuries—such as those experienced by athletes in contact sports such as boxing, football, and hockey—and a disease (chronic traumatic Encephalomyopathy) that resembles amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

20 Aug 2010

Research marks new direction to treat Pneumocystis, inflammatory diseases

A drug to treat inflammation plays a surprising role reducing the level of infection caused by an opportunistic bug that is deadly for AIDS and cancer patients and others with weakened immune systems.

20 Aug 2010

After multiple medevac crashes, NTSB wants increased safety technology

USA Today: "The National Transportation Safety Board (NTSB) is calling on regulators to require new lifesaving technologies on many air ambulances, including night-vision goggles, terrain avoidance computers and autopilot controls.

20 Aug 2010

Medical News

SRI and Taiho collaborate to advance clinical development of TAS-108 breast cancer program

Palliative care recipients live longer and in less pain, study finds

Scientists discover genetic flaw that causes facioscapulohumeral muscular dystrophy

Quark Pharmaceuticals announces option agreement with Novartis for QPI-1002 siRNA drug

Moderate alcohol in family setting can prevent young people from binge drinking: Study

FDA Advisory Committee votes in favor of expanding pain indications for Eli Lilly's Cymbalta

Business Group: Large employers grappling with health law changes

Celgene receives Japan's MHLW approval for REVLIMID in deletion 5q myelodysplastic syndrome patients

Study finds black women with SLE develop cardiovascular disease at early age

Renin test can predict appropriate drugs for BP patients: Study

Study suggests elective surgical repair is safe intervention for abdominal aortic aneurysm

Grand Junction, Colorado: Still the health care poster child

Muscle mass plays key role in cancer survival: Research

SIGVARIS joins Vascular Disease Foundation's National Corporate Round Table

MUH performs first intracranial radiosurgery with Leksell Gamma Knife Perfexion system

Model explains mechanical cause of high blood pressure

Binge drinking increases cardiovascular disease risk: Research

First pathological evidence of link between repeated head injuries and chronic traumatic Encephalomyopathy

Research marks new direction to treat Pneumocystis, inflammatory diseases

After multiple medevac crashes, NTSB wants increased safety technology

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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