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iTherX commences ITX-5061 Phase 1b study in patients with HCV

iTherX, a pharmaceutical company dedicated to discovering and developing a new class of therapies for hepatitis C, today announced that it has commenced patient recruitment in an open-label, proof-of-concept Phase 1b study of its lead compound ITX-5061 in liver transplant patients with hepatitis C virus infection.

16 Mar 2011

Human growth, height, size: Reasons to be small

Almost everybody these days thinks that it is best to be tall, meaning much taller than the average traditional height of Asian populations, and even taller than the current average height of populations in high-income countries. It is also often believed – though people might be shy to admit this – that tall people are intrinsically superior to short people. The expressions 'look up to' and 'look down on' are significant.

15 Mar 2011

15 million people caring for 5 million Alzheimer’s sufferers: U.S. report card

According to a report released on Tuesday by the Alzheimer's Association, nearly 15 million Americans are now caring for a family member or friend with Alzheimer's disease or related dementias. The Association warns that these figures may rise if new therapies for Alzheimer’s are not found.

15 Mar 2011

Heavy drinking related to pancreatic cancer: Study

According to the latest research, heavy drinkers have an increased risk of dying from pancreatic cancer. The study has shown that non-smokers who have three or more drinks of hard liquor a day face a 36 percent higher risk of dying from pancreatic cancer, compared with non-drinkers. Smoking is a definite risk for pancreatic cancer. The report is published in the March 14 issue of the Archives of Internal Medicine.

15 Mar 2011

Heavy smoking dropped drastically over last four decades: Study

A new study has shown that the rate of “pack-a-day” or more smokers in the United States has fallen sharply since 1965, particularly in California. There is evidence from earlier literature that a smaller percentage of Americans smoke now than in previous decades. This new study was published online in the Journal of the American Medical Association. It shows that high-intensity smoking is also less common.

15 Mar 2011

Bits of plastic in Lean Cuisine meals bring recall

The recall notice was issued Tuesday by the U.S. Department of Agriculture and affects about 10,260 pounds of frozen spaghetti and meatballs. Food maker Nestle, in its statement, says the affected packages were produced in October. The health risk associated with this recall is low, the USDA’s Food Safety and Inspection Service explained. If the product is consumed, there is only a remote probability of adverse health consequences.

15 Mar 2011

Apeiron in antitumor substances deal with Cleveland Clinic

APEIRON Biologics AG announced that it has entered into an exclusive option to license from the Cleveland Clinic a number of novel compounds. These compounds are currently in development at Cleveland Clinic as drug candidates for treatment of various cancers, designed to fight cancer based on stimulation of the immune system. In preclinical models, they have shown anti-cancer activity and a favourable toxicity profile as orally available agents.

15 Mar 2011

Anavex to commence phase I clinical trial in Alzheimer’s disease

Anavex Life Sciences Corp. (“Anavex”) (OTCBB: AVXL) has announced that its clinical trial application (CTA) for ANAVEX 2-73, the company’s lead compound for Alzheimer’s disease, has been approved by the German regulatory health authority, BfArM. The Phase I trial of ANAVEX 2-73, which includes testing in healthy human volunteers, will commence immediately. In this Phase I program Anavex will assess the safety, maximally tolerated dose, pharmacokinetics and pharmacodynamics of ANAVEX 2-73.

15 Mar 2011

Emergency responders, insurers, communicators must factor overconfidence into disaster preparations

Past random good fortune can lull a person into a sense of security when it comes to buying flood insurance or deciding whether to evacuate from a hurricane, according to new research. Studies of both professional risk experts and the general public showed people who had experienced a “near-miss” event related to flooding or a potential hurricane, instead of taking extra precautions when faced with possible future disasters, actually behave less protectively.

15 Mar 2011

Discovery of molecular switch for the secretion of insulin

Johns Hopkins researchers believe they have uncovered the molecular switch for the secretion of insulin — the hormone that regulates blood sugar — providing for the first time an explanation of this process. In a report published online March 1 in Cell Metabolism, the researchers say the work solves a longtime mystery and may lead to better treatments for type 2 diabetes, the most common form of the disease.

15 Mar 2011

Researchers set to study impacts of space radiation on the atmosphere and aging issues worldwide

Researchers from the University of Alberta have won awards from an international research organization that will enable them to work with colleagues around the globe to address two issues with global ramifications.

15 Mar 2011

Depressed, older people who have a stroke are more likely to be dependent

People who have a stroke are more likely to be dependent if they are depressed, older or have other medical problems, according to a study published in the March 15, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology.

15 Mar 2011

Medicago receives $3.8M as second milestone payment from U.S. DARPA for cGMP vaccine facility

Medicago USA Inc., a wholly owned subsidiary of Medicago Inc., a biotechnology company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today announced it has received the second milestone payment of US$3.8 million from the Defense Advanced Research Projects Agency ("DARPA").

15 Mar 2011

Raymond Associates, BioNeutral enter global sales and distribution agreement for Ygiene antimicrobial technology

BioNeutral Group, Inc., a specialty life science technology-based company, today announced that it has entered into a global sales and distribution agreement with Raymond Associates LLC, a Service Connected Certified Disabled Veteran-Owned Business and executive management consulting firm.

15 Mar 2011

Argon acquires global rights to market, distribute Rex Medical's Option Retrievable Inferior Vena Cava Filter

Argon Medical Devices, Inc. announced today that it has entered into a definitive license agreement with Rex Medical, LP ("Rex Medical") for exclusive global rights to market and distribute the Option™ Retrievable Inferior Vena Cava Filter, an implantable device used in the prevention of Pulmonary Embolism (PE).

15 Mar 2011

Newer, more expensive treatments for prostate cancer adopted rapidly

With 180,000 men diagnosed with prostate cancer each year, it is one of the most common types of cancer in the country. For this reason, it has been cited as a good marker for health care spending in general, reflective of the greater trends across the United States.

15 Mar 2011

Omeros fourth quarter net loss increases to $7.2 million

Omeros Corporation, a biopharmaceutical company committed to discovering, developing and commercializing products focused on inflammation, bleeding and disorders of the central nervous system, today announced financial results for the fourth quarter and year ended December 31, 2010.

15 Mar 2011

Research links frequent prescribing to opioid-related deaths

Some physicians are prescribing opioids such as OxyContin 55 times as often as others, according to a new study led by St. Michael's Hospital and the Institute for Clinical Evaluative Sciences (ICES). The study found most opioid-related deaths occur among patients treated by physicians who frequently prescribe opioids, suggesting doctors who prescribe a lot of opioids may not be doing so safely.

15 Mar 2011

Trend rising for deaths of children in cars and trucks

Sadly, March 8th marked the first child vehicular tragedy of the year when a mother came out of work only to realize she left her 6 month year old in the car. This preventable, yet horrific accident occurs more often than one would think.

15 Mar 2011

First Edition: March 15, 2011

Today's headlines include reports about the pace of legal challenges to the health law as well as ongoing congressional attempts to reach partisan agreement on a short-term budget bill to avert a government shutdown.

15 Mar 2011