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Self assembly approaches to improve DNA sequencing

In an innovation critical to improved DNA sequencing, a markedly slower transmission of DNA through nanopores has been achieved by a team led by Sandia National Laboratories researchers.Solid-state nanopores sculpted from silicon dioxide are generally straight, tiny tunnels more than a thousand times smaller than the diameter of a human hair. They are used as sensors to detect and characterize DNA, RNA and proteins. But these materials shoot through such holes so rapidly that sequencing the DNA passing through them, for example, is a problem.

31 Jul 2010

Florida judge blocks state constitutional amendment on federal health law

A Leon County circuit judge today blocked a proposed [state] constitutional amendment that targets the federal health-reform law, saying Florida Republican lawmakers included wording in the proposal that would mislead voters. Judge James O. Shelfer said the proposal --- dubbed by lawmakers as the 'Health Care Freedom' amendment --- should not go on the November ballot. He described wording in a ballot summary as 'manifestly misleading.'

31 Jul 2010

Circuit Court Judge removes Amendment 9 from November ballot

Today, Circuit Court Judge James Shelfer removed Amendment 9—modeled after the American Legislative Exchange Council's (ALEC) Freedom of Choice in Health Care Act now proposed in 42 states—from the November ballot. Florida Attorney General Bill McCollum is expected to appeal to Florida's Supreme Court.

31 Jul 2010

Delta Dental launches updated website for Spanish-language speakers

Spanish-language speakers can now more easily find up-to-date oral health information and personal benefit details, thanks to an updated website launched by a group of Delta Dental companies.

31 Jul 2010

Idaho Technology signs licensing agreement with E. I. du Pont de Nemours

Idaho Technology, Inc. has signed a licensing agreement with E. I. du Pont de Nemours and Company acting through its DuPont Qualicon Business covering reagents or methods using SYBR® Green I technology and post-PCR melting curve analysis.

31 Jul 2010

HealthSouth plans new rehabilitation hospital in northwest Houston

HealthSouth Corporation today announced plans to begin construction of a new 40-bed inpatient rehabilitation hospital in the Cypress area of northwest Houston in the fourth quarter. In connection with such plans, HealthSouth has signed a contract to purchase a 6-acre tract of land from an affiliate of Caldwell Companies, based in Houston. The land is located on the northeast corner of Highway 290 and FM 1960 in Houston.

31 Jul 2010

Patients with malignant gastrointestinal disease show high prevalence of malnutrition

Malnutrition is an important factor, influencing both morbidity and recovery after surgery. The early detection of nutritional risk would allow early intervention, which may prevent later complications. A traditional nutritional assessment often includes dietary and medical evaluations to identify significant weight loss over time, significantly low or high body weight(BW), skinfold thickness, serum nutritional factor levels and functional measurements of muscle strength.

31 Jul 2010

Researchers receive $4.7M contract to develop drugs to improve soldiers' performance at high altitude

Jonathan Stamler, MD, Director of the Institute for Transformative Molecular Medicine and the Robert S. and Sylvia K. Reitman Family Foundation Distinguished Chair in Cardiovascular Innovation at the Case Western Reserve University and University Hospitals Harrington-McLaughlin Heart & Vascular Institute, has recently received a $4.7 million contract from the Defense Advanced Research Projects Agency to fund the development of a new class of drugs that will selectively dilate blood cells under hypoxia (lack of oxygen in the body's tissues) and thereby enhance soldiers' performance at high altitude.

31 Jul 2010

Blumenthal defends hew health IT rules to Utah leaders

David Blumenthal, the national coordinator for health information technology for the U.S. Department of Health and Human Services, "defended the administration's new plans against critics who say the watered-down rules miss an opportunity to lower costs and improve patient care," The Salt Lake Tribune reports.

31 Jul 2010

Galangin mediates apoptosis of hepatocellular carcinoma cells through mitochondrial pathway: Study

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, particularly in China. However, HCC remains one of the more difficult cancers to treat. It is important to screen for new anti-cancer drugs. A number of dietary compounds possess anti-cancer properties. These dietary compounds may modify the activity of specific targets that control cell proliferation and apoptosis. Galangin could inhibit the methoxyresorufin O-demethylase activity of CYP1A2, CYP1A1 and P-form phenolsulfotransferase.

31 Jul 2010

Abortion rights supporters, children's groups, GOP pushing back on various health law provisions

"Elective abortions will be prohibited and people with pre-existing conditions will be able to get comprehensive benefits without paying any more than healthy people, under new federal regulations for high-risk health insurance pools released ... by the Obama administration," according to Kaiser Health News.

31 Jul 2010

Study finds ST131 a major cause of antimicrobial-resistant E. coli infections

The new strain, ST131, was a major cause of serious antimicrobial-resistant E. coli infections in the United States in 2007, researchers found. This strain has been reported in multiple countries and encountered all over the United States. In the study, researchers analyzed resistant E. coli isolates collected during 2007 from hospitalized patients across the country. They identified 54 ST131 isolates, which accounted for 67 percent to 69 percent of E. coli isolates exhibiting fluoroquinolone or extended-spectrum cephalosporin resistance.

31 Jul 2010

Resveratrol suppresses inflammation in humans: Research

Resveratrol, a popular plant extract shown to prolong life in yeast and lower animals due to its anti-inflammatory and antioxidant properties, appears also to suppress inflammation in humans, based on results from the first prospective human trial of the extract conducted by University at Buffalo endocrinologists.

31 Jul 2010

Water Street Healthcare Partners acquires Medical Specialties Distributors

Water Street Healthcare Partners, a leading private equity firm focused exclusively on health care, announced today that it has acquired Medical Specialties Distributors, LLC (MSD). Headquartered in Stoughton, Massachusetts, MSD is the nation's leading provider of infusion products, supplies, biomedical services and technology solutions to the growing home infusion therapy market. The acquisition expands Water Street's current group of health care companies to 12.

From Baxter International Inc. 31 Jul 2010

Measuring GAPDH inhibiting antibodies can result in long-term treatment for MS

UCI immunologists have found that testing for increased levels of antibodies that inhibit energy production in neurons can detect axon and neuron degeneration in multiple sclerosis earlier than existing diagnostic tools.

31 Jul 2010

The House fails to pass aid measure for sick 9/11 responders

The Associated Press: "A bill that would have provided up to $7.4 billion in aid to people sickened by World Trade Center dust fell short in the House on Thursday, raising the possibility that the bulk of compensation for the ill will come from a legal settlement hammered out in the federal courts." The measure failed to draw the necessary two-thirds majority. Democrats had opted for this procedural route rather than a simple majority because it blocked potential GOP amendments.

31 Jul 2010

Researchers suggest soybean isoflavones enhance bone health

Scientists already know much about the more than 200 bones that make up your body. But mysteries remain regarding the exact role that many natural compounds in foods might play in strengthening our skeletons. Those compounds include estrogen-like substances known as soybean isoflavones.

31 Jul 2010

Vitacost.com second-quarter net sales increase 14% to $54.0 million

Vitacost.com, Inc., a leading online retailer and direct marketer of health and wellness products, today reported preliminary financial results for the second quarter ended June 30, 2010.

31 Jul 2010

Scientists identify enzyme to prevent beta-amyloids formation in Alzheimer patients

The brains of Alzheimer patients have high accumulations of the material beta-amyloid, which appear in the form of plaques. The precursors of these plaques are believed to be the underlying cause of the nerve cell loss that leads to the disruptions in memory that characterize Alzheimer's disease. The main aim of many Alzheimer therapies is therefore to inhibit the formation of beta-amyloid. Since beta-amyloid is cleaved from the so-called amyloid precursor protein (APP), scientists have focused on stopping the two enzymes that attack the precursor protein. These act like molecular scissors and cut out the beta-amyloid fragment. Blocking these scissors precludes the formation of beta-amyloid.

31 Jul 2010

CD74 can serve as prognostic marker for colorectal cancer

CD74 is a protein that is expressed in and on cells of the immune system, such as B lymphocytes and antigen presenting cells. This protein is known for its function in facilitating antigen presentation enabling the immune response. Additionally, Professor Shachar's lab has previously shown that CD74 serves as a survival receptor on cells of the immune system, and that its stimulation by its natural ligand -migration inhibitory factor (MIF)- prevents apoptosis (self destruction) of these cells. It was shown that CD74 is markedly expressed on numerous tumors - hematologic as well as epithelial, and can serve as a prognostic marker. CD74's expression and function on colon intestinal epithelial cells is controversial.

31 Jul 2010