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RG7204 Phase III study shows significant survival benefit in patients with metastatic melanoma

Genentech, a member of the Roche Group, today announced that BRIM3, a Phase III clinical study of RG7204, met its co-primary endpoints showing a significant survival benefit in people with previously untreated BRAF V600 mutation-positive metastatic melanoma.

19 Jan 2011

Federal government requests oral arguments in Michigan appeal of health law challenge

In this case, which was brought by a conservative law center, the plaintiff is seeking to overturn a lower court decision that found the health overhaul to be constitutional.

19 Jan 2011

New GORE VIABAHN Endoprosthesis is now available in Europe

W. L. Gore & Associates today announced the European availability of the GORE VIABAHN Endoprosthesis on a lower profile delivery system. The announcement came during the Leipzig Interventional Course in Germany, where European interventionalists gathered to discuss new approaches in treating patients suffering from peripheral artery disease.

19 Jan 2011

New project on developing countermeasures for natural and intentional exposure to disease pathogens

Researchers at Dana-Farber Cancer Institute have received a $5.6 million grant from the Defense Advanced Research Projects Agency (DARPA) and the Army Research Office (ARO) to develop transient immunity against known, unknown, naturally occurring, or engineered disease-causing pathogens. The ultimate goal is to develop a viable countermeasure to an unknown pathogen within seven days of receiving it in a laboratory.

19 Jan 2011

Arrowhead increases ownership in Calando's outstanding equity to 79%

Arrowhead Research Corporation today announced that it has invested $1 million in its majority owned subsidiary, Calando Pharmaceuticals, and converted approximately $8M of Calando debt to Arrowhead into equity. Arrowhead now owns approximately 79% of Calando's outstanding equity.

19 Jan 2011

Neuroform EZ Stent System helps neurosurgeons to treat brain aneurysms

A new device to treat brain aneurysms with stents improves access to the blood vessels allowing endovascular neurosurgeons to offer the minimally invasive technique to patients with complex cases. Dr. Demetrius Lopes, an endovascular neurosurgeon at Rush University Medical Center, was the first in the U.S. to use the new delivery system, called the Neuroform EZ Stent System.

19 Jan 2011

Positive preliminary results from Soligenix's SGX202 in GARS model

Soligenix, Inc., a late-stage biopharmaceutical company, announced today promising preliminary results from a preclinical study of SGX202 in a canine gastrointestinal acute radiation syndrome model.

19 Jan 2011

Quality of care and reimbursements will go down under Healthcare Reform Act: Survey

The newly released 2011 Thomson Reuters - HCPlexus National Physicians Survey (NPS) links doctors' fears that their pay will go down under the Patient Protection and Affordable Care Act (PPACA), commonly called Healthcare Reform Act (HCRA), with their concerns that the quality of care will also deteriorate. The study includes responses from 2,958 doctors of varying specialties and practice types, from all 50 states plus the District of Columbia.

19 Jan 2011

Cancer cells brought back under normal control

Scientists at The University of Nottingham have brought cancer cells back under normal control — by reactivating their cancer suppressor genes. The discovery could form a powerful new technology platform for the treatment of cancer of the breast and other cancers.

19 Jan 2011

Molecular imaging procedure may detect beta-amyloid in brain, increase accuracy of AD diagnosis

Preliminary research suggests that use of a type of molecular imaging procedure may have the ability to detect the presence of beta-amyloid in the brains of individuals during life, a biomarker that is identified during autopsy to confirm a diagnosis of Alzheimer disease, according to a study in the January 19 issue of JAMA.

19 Jan 2011

Common genetic risk factor for heart failure in Caucasians also linked to kidney function

Nearly five million Americans live with heart failure, with as many as 700,000 new cases diagnosed each year. In addition to lifestyle factors, scientists have shown that heart failure has a strong heritable component, but identifying the responsible genes has been a major challenge. Now, new research has identified a common genetic risk factor for heart failure in Caucasians that is also linked to kidney function.

19 Jan 2011

Scripps Research receives NIH grant to develop therapies for circadian rhythm disorders

The Scripps Research Institute has been awarded $3.17 million over four years to develop compounds that will counteract disruptions of the human biological clock - the circadian rhythm that regulates our patterns of activity and rest over a 24-hour daily cycle.

19 Jan 2011

Higher fruit and vegetable intake lowers risk of dying from ischaemic heart disease

A European study investigating the links between diet and disease has found that people who consume more fruit and vegetables have a lower risk of dying from ischaemic heart disease - the most common form of heart disease and one of the leading causes of death in Europe.

19 Jan 2011

Positive results from PLX4032 Phase 3 Trial in patients with metastatic melanoma

Plexxikon today announced positive data from an interim analysis of the BRIM3 trial, a large multi-center Phase 3 clinical study of PLX4032 in patients with previously untreated metastatic melanoma with the BRAF mutation. Patients treated with PLX4032 had an improved overall survival compared to patients treated with dacarbazine, the current standard of care.

19 Jan 2011

MMA calls for delay in release of Medica's physician rating program

The Minnesota Medical Association has asked Medica to delay the January 19 scheduled public release date of their individual physician rating program, known as the Premium Designation Program.

19 Jan 2011

Aastrom secures US patent for autologous cell therapy product

Aastrom Biosciences, a leading developer of expanded autologous cellular therapies for severe, chronic cardiovascular diseases, today announced that it has been granted a U.S. patent which provides composition of matter protection for its investigational expanded autologous cell therapy product.

19 Jan 2011

Revolution R Enterprise implemented at CardioDX

Revolution Analytics, the leading provider of commercial software and support for the popular open source R statistics language, today announced the successful implementation of its signature product, Revolution R Enterprise, by biostatisticians at CardioDX, a genomic research firm.

19 Jan 2011

Study: Brain's 'autopilot' network may aid in early diagnosis of Alzheimer's disease

Watching the brain's "autopilot" network in real time may help determine the onset of cognitive decline and potentially aid in making an early diagnosis of Alzheimer's disease, according to researchers at Duke University Medical Center.

19 Jan 2011

Antioxidants may cause fertility problems in females

Antioxidants are sold over the counter everywhere. They're added to food, drink and face cream. But according to Prof. Nava Dekel of the Biological Regulation Department, we still don't have a complete understanding of how they act in our bodies. New research by Dekel and her team, recently published in the Proceedings of the National Academy of Sciences USA (PNAS), has revealed a possible unexpected side effect of antioxidants: They might cause fertility problems in females.

19 Jan 2011

Magnetic maneuverable capsule safe and well-tolerated in the stomach

A study from researchers in Germany showed that magnetic maneuvering of a modified capsule endoscope in the stomach of healthy volunteers under clinical conditions is safe, well-tolerated, and technically feasible. Maneuverability of the capsule within the stomach was excellent and visualization of the gastric mucosa, the inner lining of the stomach, was satisfactory in the majority of subjects.

19 Jan 2011

Medical News

RG7204 Phase III study shows significant survival benefit in patients with metastatic melanoma

Federal government requests oral arguments in Michigan appeal of health law challenge

New GORE VIABAHN Endoprosthesis is now available in Europe

New project on developing countermeasures for natural and intentional exposure to disease pathogens

Arrowhead increases ownership in Calando's outstanding equity to 79%

Neuroform EZ Stent System helps neurosurgeons to treat brain aneurysms

Positive preliminary results from Soligenix's SGX202 in GARS model

Quality of care and reimbursements will go down under Healthcare Reform Act: Survey

Cancer cells brought back under normal control

Molecular imaging procedure may detect beta-amyloid in brain, increase accuracy of AD diagnosis

Common genetic risk factor for heart failure in Caucasians also linked to kidney function

Scripps Research receives NIH grant to develop therapies for circadian rhythm disorders

Higher fruit and vegetable intake lowers risk of dying from ischaemic heart disease

Positive results from PLX4032 Phase 3 Trial in patients with metastatic melanoma

MMA calls for delay in release of Medica's physician rating program

Aastrom secures US patent for autologous cell therapy product

Revolution R Enterprise implemented at CardioDX

Study: Brain's 'autopilot' network may aid in early diagnosis of Alzheimer's disease

Antioxidants may cause fertility problems in females

Magnetic maneuverable capsule safe and well-tolerated in the stomach

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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