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Oncolytics opens enrollment in REOLYSIN combination U.S. Phase I colorectal cancer study

Oncolytics Biotech Inc. announced today that a U.S. Phase I study of REOLYSIN® in combination with FOLFIRI (Folinic Acid (leucovorin) + Fluorouracil (5-FU) + Irinotecan) in patients with oxaliplatin refractory/intolerant Kras mutant colorectal cancer (REO 022) is now open to enrollment. The principal investigator is Dr. Sanjay Goel of the Montefiore Medical Center at The Albert Einstein College of Medicine in New York.

10 Jan 2011

Civitas receives $20 million Series A financing

Civitas Therapeutics, Inc., a privately held biopharmaceutical company focused on developing transformative pulmonary delivery therapies, announced today that it has secured a $20 million Series A financing from founding investor, Longitude Capital, along with co-lead Canaan Partners. The proceeds of the financing will be primarily used to advance Civitas' lead program for treating patients with Parkinson's disease through clinical proof-of-concept.

10 Jan 2011

Omega-3 fatty acid may help protect against traumatic brain injury

Animal experiments suggest that taking the omega-3 fatty acid docosahexanoic acid (DHA) might offer a new way of protecting against traumatic brain injury (TBI), reports the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

10 Jan 2011

95.6% of WTC survivors report posttraumatic stress symptoms

Nearly 10 years after the greatest human-made disaster in U.S. history-- the destruction of the World Trade Center (WTC) towers -- there has been little research documenting the attacks' consequences among those most directly affected -- the survivors who escaped the World Trade Center towers.

10 Jan 2011

Bioheart reports positive data from adipose derived stem cells study in critical limb ischemia

Bioheart, Inc. announced positive efficacy data has been reported from the registry study of bone marrow and adipose derived stem cells for the treatment of end stage critical limb ischemia with wounds. Vaclav Prochazka MD, PhD, MSc., of University Hospital Ostrava, Czech Republic presented data at the American Academy of Anti-Aging Medicine Conference in Las Vegas last month.

10 Jan 2011

Research suggests novel therapeutic approach for Huntington's Disease

Hope for new ways of treating devastating neurodegenerative disorders such as Huntington's disease has been raised by a trans-Atlantic team of researchers thanks to the use of cutting-edge genetic techniques.

10 Jan 2011

DGT Holdings completes reverse/forward stock split

DGT Holdings Corp. announced today that it has completed the previously announced reverse stock split at a ratio of one-for-fifty and a forward stock split at a ratio of four-for-one. All shareholders owning fewer than fifty shares and all fractional shares remaining following the forward stock split have been cancelled and shareholders will receive a cash payment based on the ten day average closing price of the common stock prior to the splits.

10 Jan 2011

Key Equipment Finance and Hitachi Medical Systems America enter new partnership

Key Equipment Finance, one of the nation's largest bank-held equipment finance companies and an affiliate of KeyCorp today announced that the company has entered into an exclusive, long term, program agreement with Hitachi Medical Systems America. Hitachi Medical Systems America is the U.S. distributor of Hitachi Medical Corporation's diagnostic imaging products.

10 Jan 2011

Takeda San Francisco and Pieris enter Anticalin scaffold technology collaboration

Takeda San Francisco (TSF) and Pieris AG have signed a drug discovery partnership agreement under which Pieris will apply its Anticalin(R) scaffold technology to deliver protein therapeutic candidates to Takeda, both companies announced today. The deal initially will focus on first-in-class drug discovery efforts around a predetermined Takeda target.

10 Jan 2011

Illumina announces next generation of iSelect custom genotyping products

Illumina, Inc. today announced its next generation of iSelect custom genotyping products that allow researchers to design custom arrays containing from 3,000 up to 1,000,000 markers, with the flexibility to add supplemental content to their array designs.

From Illumina, Inc. 10 Jan 2011

FDA grants Exelixis XL184 orphan drug designation for treatment of medullary thyroid cancer

Exelixis, Inc. today announced that the U.S. Food & Drug Administration (FDA) has granted orphan drug designation to XL184 for treatment of follicular, medullary, and anaplastic thyroid carcinoma, and metastatic or locally advanced papillary thyroid cancer. A pivotal phase 3 trial of XL184 is ongoing in patients with medullary thyroid cancer (MTC) and the company expects to release top-line phase 3 results in the first-half of 2011 and potentially file a New Drug Application (NDA) for the compound in the second-half of 2011.

10 Jan 2011

First Edition: January 10, 2011

Health policy headlines include reports about the decision to delay the scheduled House vote on repealing the health law.

10 Jan 2011

KYTHERA and Intendis initiate ATX-101 European Phase III studies for reduction of submental fat

KYTHERA Biopharmaceuticals, Inc. and Intendis, Bayer HealthCare's dermatology business, today announced the initiation of two European Phase III studies evaluating ATX-101, a first-in-class injectable adipolytic agent, for the reduction of localized fat under the chin (submental fat).

10 Jan 2011

LabCorp to market On-Q-ity's circulating tumor cell platform

On-Q-ity, a next-generation oncology diagnostics company developing personalized and predictive tests to improve cancer therapy effectiveness, today announced a strategic alliance with Laboratory Corporation of America Holdings® (LabCorp). LabCorp will market On-Q-ity's novel and proprietary circulating tumor cell (CTC) platform to the biopharma industry to greatly accelerate and improve the cancer drug discovery and development process.

10 Jan 2011

Researchers describe crucial initial steps taken by measles virus attachment proteins with receptors

Mayo Clinic researchers have shown that proteins on the surface of a cell twist a viral protein into position, allowing the virus to start infection and cause disease, all in a movement as graceful as a ballroom dance. The findings appear in the current online issue of Nature Structural & Molecular Biology.

10 Jan 2011

New study finds extending term of exclusive access can lead to higher drug costs in short term

A new study in the January 2011 issue of Health Affairs is the first to calculate the financial and social costs of limiting access to trial data — and finds that extending the term of exclusive access will lead to higher drug costs in the short term but also to more than 200 extra drug approvals and to greater life expectancy in the next several decades.

10 Jan 2011

Food price rise will affect 'millions,' FAO economist says

Abdolreza Abbassian, an economist with the U.N. Food and Agriculture Organization (FAO), on Friday "warned of a 'worrying rise' in food prices which will affect millions of people following unexpected shortfalls in major cereals owing to bad weather in 2010," Agence France-Presse reports.

10 Jan 2011

Slowing engines of mitochondria could extend life

In making your pro-longevity resolutions, like drinking more red wine and maintaining a vibrant social network, here's one you likely forgot: dialing down your mitochondria. It turns out that slowing the engines of these tiny cellular factories could extend your life-an observation relevant not only to aging research but to our understanding of how cells communicate with each another.

10 Jan 2011

Hospice of Michigan offers toolkit to help people on end-of-life decision making and planning

Hospice of Michigan offers a complete toolkit to empower individuals and families to take control of end-of-life decision making and planning. The free resource is the www.haveyouhadthetalk.org website from which a toolkit can be downloaded and printed for free.

10 Jan 2011

Colorectal cancer screening disparities in certain regions

Individuals from certain areas of the United States are more likely to get screened for colorectal cancer than those from other areas, particularly when comparing non-whites living in different parts of the country. That is the conclusion of a new study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. Additional research is needed to better understand how colorectal cancer screening disparities develop in some regions and not in others.

10 Jan 2011

Medical News

Oncolytics opens enrollment in REOLYSIN combination U.S. Phase I colorectal cancer study

Civitas receives $20 million Series A financing

Omega-3 fatty acid may help protect against traumatic brain injury

95.6% of WTC survivors report posttraumatic stress symptoms

Bioheart reports positive data from adipose derived stem cells study in critical limb ischemia

Research suggests novel therapeutic approach for Huntington's Disease

DGT Holdings completes reverse/forward stock split

Key Equipment Finance and Hitachi Medical Systems America enter new partnership

Takeda San Francisco and Pieris enter Anticalin scaffold technology collaboration

Illumina announces next generation of iSelect custom genotyping products

FDA grants Exelixis XL184 orphan drug designation for treatment of medullary thyroid cancer

First Edition: January 10, 2011

KYTHERA and Intendis initiate ATX-101 European Phase III studies for reduction of submental fat

LabCorp to market On-Q-ity's circulating tumor cell platform

Researchers describe crucial initial steps taken by measles virus attachment proteins with receptors

New study finds extending term of exclusive access can lead to higher drug costs in short term

Food price rise will affect 'millions,' FAO economist says

Slowing engines of mitochondria could extend life

Hospice of Michigan offers toolkit to help people on end-of-life decision making and planning

Colorectal cancer screening disparities in certain regions

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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