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Clinical data of pomalidomide for treating patients with multiple myeloma presented at ASH 2010

Celgene International Sàrl today announced that its next IMiD compound, pomalidomide, was evaluated in three separate investigational trials of patients with multiple myeloma who were relapsed or refractory after prior treatments including lenalidomide, thalidomide and bortezomib. The clinical data were presented at the 52nd Annual Meeting of the American Society of Hematology in Orlando, Florida.

9 Dec 2010

DPT granted FDA approval to manufacture Collagenase SANTYL Ointment for wound care

DPT Laboratories, Ltd., a pharmaceutical contract development and manufacturing organization, announced today that it received FDA approval to manufacture commercial supplies of a leading sterile ointment for wound care at its Center of Excellence for Sterile & Specialty Products in Lakewood, N.J. Beginning this month, Healthpoint will ship commercial lots of Collagenase SANTYL® Ointment produced at DPT's Lakewood facility to its North American customers.

9 Dec 2010

ADHD, developmental RD have common genetic influences: Study

Attention Deficit Hyperactivity Disorder and developmental reading disability are complex childhood disorders that frequently occur together; if a child is experiencing trouble with reading, symptoms of ADHD are often also present.

9 Dec 2010

NIH to create new translational science center

National Institutes of Health (NIH) Director Francis Collins on Tuesday announced the agency is moving forward on plans to create a new research center focused on translational science, after NIH's advisory board voted to create the new center, Science's "Science Insider" blog reports (Kaiser, 12/7).

9 Dec 2010

Euthymics's EB-1010 effective in treatment of major depressive disorder: Study

Euthymics Bioscience, Inc. today will present Phase II clinical data demonstrating that its lead product candidate EB-1010, a next-generation antidepressant, is effective for treating major depressive disorder (MDD) based on multiple standard measures of outcome for depression. EB-1010 also improved measures of anhedonia, a hallmark symptom of MDD, which is characterized by the inability to experience pleasure.

9 Dec 2010

Docs distrust hospitals; Americans divided over health law; Children's hospitals lose discounts on orphan drugs

"The successful implementation of the new health care reform law will hinge on physicians and hospitals working out trust issues with one another," according to a new PricewaterhouseCoopers survey. "The reform law requires increased collaboration and information sharing between physicians and hospitals, including through new accountable care organization arrangements, to reduce costs and increase quality."

9 Dec 2010

AJPH publishes study on importance of preventive dental treatment for pregnant women

Aetna today announced that the study, An Examination of Periodontal Treatment, Dental Care and Pregnancy Outcomes in an Insured Population, has been published online by the American Journal of Public Health.

9 Dec 2010

India, EU trade agreement will not restrict ability for India's pharmaceutical firms to export generic drugs, official says

"India and the European Union (EU) have agreed that the comprehensive bilateral trade agreement being negotiated by the two will not result in an intellectual property regime that restricts the ability of Indian pharmaceutical firms to export generic or off-patent drugs by being far more stringent than the TRIPS [Trade-Related Aspects of International Property Rights] regime of the World Trade Organization," LiveMint.com reports in an article that describes recent debates over the agreement.

9 Dec 2010

Alkermes announces preliminary results from ALKS 33 Phase 2 study in alcohol dependence

Alkermes, Inc. today announced preliminary results from a phase 2 clinical study of ALKS 33, one of Alkermes' proprietary candidates for the treatment of reward disorders and other central nervous system (CNS) disorders. The 12-week study was designed to assess the safety and efficacy of daily oral administration of three different dose levels of ALKS 33 compared to placebo in 400 alcohol dependent patients.

9 Dec 2010

Estrogen receptor beta inactivates critical genes, arrests cancer cell growth

Bionovo, today announced the publication of a study demonstrating that ERb causes cancer cell growth arrest by inactivating critical genes and enzymes responsible for cell growth. These results provide evidence that drugs that stimulate the production of or activate ERb are potential new therapies to prevent breast cancer.

9 Dec 2010

Three drug companies to pay $421 million in fraud settlement

Los Angeles Times: Three pharmaceutical firms — Roxane, Abbott Laboratories and B. Braun Medical — "agreed to pay more than $421 million to settle claims of defrauding Medicare and Medicaid — the latest in a string of large healthcare fraud settlements announced by the Justice Department. The drug companies charged one set of prices to doctors and pharmacies but reported another set of inflated figures that were used as benchmarks by government insurers reimbursing healthcare providers, authorities said" (Zajac, 12/8).

9 Dec 2010

AltheaDx partners with Compendia Bioscience to launch Breast Cancer Segregation Panel Assay

AltheaDx, Inc. today announced the formation of a strategic partnership with Compendia Bioscience to combine their respective core capabilities in assay development, validation and bioinformatics. The two companies will jointly create novel products and services focused on cancer biomarker discovery and subsequent development of tests that predict patient outcomes in clinical trials.

9 Dec 2010

Organovo releases data on bioprinted blood vessels

Organovo, Inc., a regenerative medicine company focused on bioprinting technology, today announced the release of data on the first fully bioprinted blood vessels. Data was presented at the Tissue Engineering and Regenerative Medicine International Society (TERMIS) meeting in Orlando, Florida. The blood vessels were created through the use of the NovoGen MMX Bioprinter, Organovo's proprietary platform for the creation of 3D tissue constructs.

9 Dec 2010

Genetics in Medicine: Women who carry high-risk BRCA mutations opt for surgery

In women who test positive for BRCA 1/2 mutations associated with a high risk of breast or ovarian cancer, some key psychological factors influence the decision to undergo risk-reducing surgery, reports the December Genetics in Medicine, the official peer-reviewed journal of The American College of Medical Genetics.

8 Dec 2010

Medulloblastoma subtypes are separate diseases with different origins

International effort led by St. Jude Children's Research Hospital scientists is expected to fuel development of targeted therapies and aid the search for unique combinations of cells and mutations that lead to other cancers.

8 Dec 2010

Private insurers, employee wellness programs seek to control costs

Modern Healthcare: "Private insurers may be better at controlling healthcare costs than Medicare, according to a Health Affairs study of two Texas cities. The study is a follow-up to a widely read 2009 New Yorker article by Atul Gawande that showed per-capita Medicare spending in McAllen, Texas, was 86% higher than in El Paso.

8 Dec 2010

Neurologist wins trial for defamation against Utah Medicaid Fraud Control Unit

The worst abuses in government health programs may be by officials who press false charges. Threatening criminal prosecution to try to get a physician to pay monies amounts to "extortion," admitted one prosecutor in sworn testimony published in the winter 2010 issue of the Journal of American Physicians and Surgeons (http://www.jpands.org/vol15no4/becker.pdf).

8 Dec 2010

WHO endorses rapid TB test

"The World Health Organization endorsed a new, rapid test for tuberculosis Wednesday that cuts the diagnosis time for patients from months to hours," CNN reports (Gray, 12/8).

8 Dec 2010

Myriad to acquire technology for diagnosis, prognosis of malignant melanoma

Myriad Genetics, Inc. today announced that it has signed an agreement to acquire proprietary technology for the diagnosis and prognosis of malignant melanoma using highly validated genetic markers from Melanoma Diagnostics, Inc. of Altadena, California. Under the agreement, Myriad has the right to commercialize all tests derived from the technology on a worldwide basis in exchange for upfront fees and contingent payments based upon the commercial success of the products.

8 Dec 2010

Aetna to acquire health information exchange firm for $500 million

Aetna, one of the largest U.S. insurers, is expanding its health information technology presence with its $500 million acquisition of technology firm Medicity, Bloomberg reports. "Medicity, based in Salt Lake City, offers technology that helps 760 hospitals and 125,000 physicians in the U.S. exchange medical data, according to the statement." Aetna said it financed the deal with "available resources" that wouldn't affect its financial results (Nussbaum, 12/7).

8 Dec 2010

Medical News

Clinical data of pomalidomide for treating patients with multiple myeloma presented at ASH 2010

DPT granted FDA approval to manufacture Collagenase SANTYL Ointment for wound care

ADHD, developmental RD have common genetic influences: Study

NIH to create new translational science center

Euthymics's EB-1010 effective in treatment of major depressive disorder: Study

Docs distrust hospitals; Americans divided over health law; Children's hospitals lose discounts on orphan drugs

AJPH publishes study on importance of preventive dental treatment for pregnant women

India, EU trade agreement will not restrict ability for India's pharmaceutical firms to export generic drugs, official says

Alkermes announces preliminary results from ALKS 33 Phase 2 study in alcohol dependence

Estrogen receptor beta inactivates critical genes, arrests cancer cell growth

Three drug companies to pay $421 million in fraud settlement

AltheaDx partners with Compendia Bioscience to launch Breast Cancer Segregation Panel Assay

Organovo releases data on bioprinted blood vessels

Genetics in Medicine: Women who carry high-risk BRCA mutations opt for surgery

Medulloblastoma subtypes are separate diseases with different origins

Private insurers, employee wellness programs seek to control costs

Neurologist wins trial for defamation against Utah Medicaid Fraud Control Unit

WHO endorses rapid TB test

Myriad to acquire technology for diagnosis, prognosis of malignant melanoma

Aetna to acquire health information exchange firm for $500 million

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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