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Researchers demonstrate role of HSP-90 in portal hypertension

Neural vasoregulation represents a rapid and potent mode of altering vascular tone but has not been investigated thoroughly during portal hypertension. Heat shock protein-90 is well-known to act as a molecular chaperone optimizing endothelial and neural NO-synthase enzyme activity and thus, NO production.

21 Apr 2010

Concateno bestowed Queen's Award for Enterprise

Concateno (>Europe's leading drug and alcohol test provider, has been awarded the prestigious Queen's Award for Enterprise (http://www.queensawards.org.uk/business/business.html ) in recognition of its outstanding innovation and commercial performance.

21 Apr 2010

Study investigates potential long-term effects of maternal stature on offspring mortality

Among 54 low- to middle-income countries, a mother's shorter height is associated with a higher rate of death for her children and a greater likelihood of these children being underweight and having a reduced rate of growth, according to a study in the April 21 issue of JAMA.

21 Apr 2010

A*STAR's BMRC and SIgN award grants for twelve research projects on infectious diseases and immunology

Twelve research projects on infectious diseases and immunology have been awarded grants by A*STAR's Biomedical Research Council (BMRC) and Singapore Immunology Network (SIgN) this year.

21 Apr 2010

LDR completes IDE study on Mobi-C cervical artificial disc

LDR, a privately held company with innovative spinal implants for non-fusion and fusion applications, announced completion of the 24-month follow-up phase of its two-level IDE study on the Mobi-C cervical artificial disc. Having previously finalized the 24-month follow-up phase of the one-level study earlier this year, LDR is now the first company to fully enroll and reach two-year follow-up on a concurrent one-level and two-level cervical artificial disc replacement study.

21 Apr 2010

Findings may illuminate how cancer forms and migrates

Rho proteins have been described as "molecular switches" and play a role in cell migration, cell proliferation, cell death, gene expression, and multiple other common cellular functions.

21 Apr 2010

MMRC Multiple Myeloma Genomics Initiative presented at AACR 2010

An analysis of 38 myeloma tumor genomes surveyed through extensive next-generation sequencing by the Broad Institute has revealed intriguing recurrent mutations that point to important cellular pathways which contribute to multiple myeloma. These data were revealed during an oral presentation entitled "First Impressions of the Multiple Myeloma Genome" by Todd R. Golub, MD, Director of the Cancer Program at the Eli and Edythe L. Broad Institute.

21 Apr 2010

Tea for Teal event raises $15,000 for TGen ovarian cancer research

The Anne Rita Monahan Foundation recently presented $15,000 for ovarian cancer research to the Translational Genomics Research Institute (TGen).

21 Apr 2010

Hospital mortality rates make poor diagnostic tests for quality of care

Mortality rates are a poor measure of the quality of hospital care and should not be a trigger for public inquiries such as the investigation at the Mid Staffordshire hospital, argue experts in a paper published on bmj.com today.

21 Apr 2010

Contrary to previous studies, people with Moebius syndrome lead successful lives

A smile means happiness, a frown sadness, a raised brow surprise. Even when languages and cultures differ, people have this universal form of communication. But Moebius syndrome, a rare congenital condition causing facial paralysis, can rob people of this basic connection, affecting social interaction.

21 Apr 2010

Physicians, patients sign online petition to stop Medicare Meltdown

Medicare, the foundation of America's health system, is crumbling and needs permanent repair. Yet Congress just passed major health system reform legislation without solving the Medicare problem.

21 Apr 2010

New survey shows 82% of patients select OTC products recommended by their pharmacist

According to the most recent Pharmacy Today Over-the-Counter Product Survey conducted by the American Pharmacists Association (APhA), pharmacists believe that 82 percent of consumers purchase over-the-counter products that were recommended by their pharmacist.

21 Apr 2010

"Destination therapy" for end-stage heart failure patients

Federal approval for an alternative therapy to heart transplantation led to a new lease on life for a UT Southwestern Medical Center patient who suffered from heart failure for nearly a decade.

21 Apr 2010

Researchers discover subunits of GABAB receptors in central nervous system

In the latest issue of the renowned scientific journal "Nature" researchers from the universities of Freiburg and Basel report on their discovery of previously unknown subunits of the GABAB receptors in the central nervous system. GABAB receptors are transmembrane proteins in nerve cells which are of fundamental significance for the functioning of the brain and have great therapeutical and pharmaceutical importance.

21 Apr 2010

New research shows mercury levels are higher in some tuna species

New research showing that that mercury levels are higher in some species of tuna could help consumers minimize their consumption of the silvery metal in their sushi and provide a powerful new tool for regulatory organizations.

21 Apr 2010

Simcyp wins Queen's Award for Enterprise for innovative research and development

Simcyp Limited, experts in simulating how the body deals with new drugs in development, today announces that it has won a Queen's Award for Enterprise. The award has been made in the Innovation category and reflects Simcyp's continuous development of modelling and simulation software for evaluating drugs in the safety of a computer.

21 Apr 2010

Modest weight reduction reverses immune cell damage in obese people with diabetes

Australian scientists have shown for the first time that even modest weight loss reverses many of the damaging changes often seen in the immune cells of obese people, particularly those with Type 2 diabetes.

21 Apr 2010

Study identifies the source of inherent noise in HIV gene expression

New research identifies a molecular mechanism that the human immunodeficiency virus (HIV) appears to utilize for generating random fluctuations called "noise" in its gene expression.

21 Apr 2010

Children with developmental regression at increased risk for more severe autism: Study

Kennedy Krieger Institute announced today new study results showing that when and how autism symptoms appear in the first three years of life has vital implications to a child's developmental, diagnostic, and educational outcomes.

21 Apr 2010

Hearing tests needed for children

The importance of hearing testing isn't widely understood by many parents. Parents may schedule appointments with an opthamologist for an eye exam for their children at regular intervals - but never think to similarly schedule a hearing test with an audiologist.

21 Apr 2010