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NIH awards $1.2 million EUREKA grant to study protein misfolding

Three University of Massachusetts Amherst scientists have received a four-year, $1.2 million EUREKA grant from the U.S. National Institutes of Health (NIH) to study folding and misfolding of secretory proteins in the cell's protein factory, the endoplasmic reticulum, where misfolding can lead to diseases such as cystic fibrosis and liver cirrhosis.

3 Sep 2010

National Drug Control Policy announces $22 million grant in DFC program

Gil Kerlikowske, Director of National Drug Control Policy (ONDCP), today announced $22 million in new Drug Free Communities Support Program (DFC) grants to 169 communities and 16 new DFC Mentoring grants across the country.

3 Sep 2010

Capsaicin linked to skin cancer

The September cover story of the nation's leading cancer journal, "Cancer Research," features a new study from The Hormel Institute, University of Minnesota, that links capsaicin, a component of chili peppers, to skin cancer. While the molecular mechanisms of the cancer-promoting effects of capsaicin are not clear and remain controversial, The Hormel Institute has shown a definite connection to formation of skin cancer through various laboratory studies.

3 Sep 2010

Botox maker agrees to pay $600 million for misbranding

The Associated Press: "Allergan Inc., the maker of wrinkle-smoothing Botox, has agreed to pay $600 million to settle a yearslong federal investigation into its marketing of the top-selling, botulin-based drug. The Justice Department and the company said Wednesday in a statement it will plead guilty to one misdemeanor charge of 'misbranding,' in which the company's marketing led physicians to use Botox for unapproved uses. Those included the treatment of headache, pain, spasticity and cerebral palsy in children.

3 Sep 2010

Luminal intermediate cells impact basal-like breast cancer origin: Research

New research uncovers a case of mistaken identity that may have a significant impact on future breast cancer prevention and treatment strategies. The study, published by Cell Press in the September 3rd issue of the journal Cell Stem Cell, suggests that despite their "stem cell-like" characteristics, most aggressive breast tumors are not derived from normal mammary gland stem cells.

3 Sep 2010

Consultation with plastic surgeon impacts decision to perform breast reconstruction: Study

When breast cancer surgeons regularly confer with plastic surgeons prior to surgery, their patients are more likely to have reconstruction, according to a new study led by researchers at the University of Michigan Comprehensive Cancer Center.

3 Sep 2010

Researchers unveil prototype model of first implantable artificial kidney

UCSF researchers today unveiled a prototype model of the first implantable artificial kidney, in a development that one day could eliminate the need for dialysis.

3 Sep 2010

Researchers receive BioBank DNA samples to unveil psoriasis genetics

Millions of Americans struggling with psoriasis and psoriatic arthritis are one step closer to a cure with the release of the first National Psoriasis Victor Henschel BioBank DNA samples for use in research at the University of Michigan Health System; research that hopes to uncover the unknowns about the genetics of psoriasis and psoriatic arthritis.

3 Sep 2010

Egg recall raises questions about FDA

The recent salmonella outbreak/egg recall is raising questions about whether the FDA is fulfilling its regulatory role, PBS' NewsHour reports. "For the past few years, it's been one food safety scare after another. There was E. coli-laced spinach, salmonella-tainted peppers. ... There have also been problems with drugs. The ingredients in a contaminated blood thinner came from China.

3 Sep 2010

Diabetes drug metformin exhibits potential against tobacco-induced lung tumors

Metformin, a drug commonly used to treat type 2 diabetes, shows potential in the prevention of tobacco-induced lung tumors, according to early research conducted at the National Cancer Institute (NCI).

3 Sep 2010

Greater Cincinnati receives award to improve health care system

U.S. Department of Health and Human Services Secretary Kathleen Sebelius announced today that the Greater Cincinnati community was awarded a $13.8 million Beacon Community cooperative agreement.

3 Sep 2010

USA Today: Unprecedented drop in medical spending

The growth rate of health spending is at its slowest in a half-century, "a sign that people are forgoing medical care during the recession," according to an "analysis of government data" by USA Today.

3 Sep 2010

Rexahn Pharmaceuticals publishes research article on RX-8243 anti-tumor activity

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company developing and commercializing potential best in class oncology and CNS therapeutics, today announced the publication of a research article in Bioorganic & Medicinal Chemistry Letters on the anti-tumor activity of RX-8243 and its analogues.

3 Sep 2010

FDA approves Ascension Orthopedics' TITAN Modular Total Shoulder System

Ascension Orthopedics, Inc., the world leader in PyroCarbon orthopedic devices, announces FDA approval to market the TITAN™ Modular Total Shoulder System. This newly designed system redefines modularity by providing multiple surgical solutions for shoulder arthroplasty with one implant system.

3 Sep 2010

CaPre drug candidate shows promising result on CRP level reduction

Acasti Pharma Inc., a subsidiary of Neptune Technologies & Bioressources Inc. reports significant results on the effects of its anti-dyslipidemic investigational drug candidate CaPre on C-reactive protein (CRP) levels, a biomarker of CardioVascular Disease risk (CVD) and associated with diabetes and obesity.

3 Sep 2010

Opinions: Pakistan's rebuilding; Kenya's constitution; Development financing; Africa's black market for malaria drugs

A Washington Post editorial encouraging the U.S. to generously support Pakistan as it recovers from major flooding, states: the "humanitarian interest is heightened by Pakistan's centrality to America's national security interests. The Obama administration must seize this chance to deepen and broaden what is already a large commitment, lest Pakistan become even more of a breeding ground for terrorism."

3 Sep 2010

Researchers discover novel compound to combat drug resistant malaria

Novartis announced today that scientists at the Novartis Institute for Tropical Diseases (NITD), in collaboration with researchers from the Genomics Institute of the Novartis Research Foundation (GNF), the Swiss Tropical and Public Health Institute and The Scripps Research Institute have discovered a novel compound that shows promise as a next generation treatment for drug resistant malaria.

3 Sep 2010

Shanghai SynTheAll Pharmaceuticals receives ISO 14001 certification

WuXi PharmaTech, a leading pharmaceutical, biotechnology and medical device research and development outsourcing company with operations in China and the United States, announced today that its manufacturing subsidiary, Shanghai SynTheAll Pharmaceuticals Co. Ltd. (STA) passed the ISO 14001: 2004 inspection conducted by SGS Group on July 1 and received formal ISO 14001 certification on July 30.

3 Sep 2010

Cerebral palsy risk rises in post term babies: Study

Babies born past their due dates – at 42 weeks or later, are at increased risk for cerebral palsy compared to those born at 40 weeks, according to new research. That said, the actual risk of cerebral palsy remains low. According to the CDC one in 303 children have some type of cerebral palsy. Common symptoms may include movement problems, muscle stiffness, poor muscle tone, and spasticity. The symptoms are thought to result from injury to the brain as a fetus or early in infancy.

2 Sep 2010

Lack of sleep linked to depression and anxiety disorders in young

According to Australian research, youngsters getting inadequate sleep are at risk of mental ailments. Researcher Nicholas Glozier of the University of Sydney said, the increase in incidence of mental ailments in the young has been puzzling health experts. The answer may lie in inadequate sleep.

2 Sep 2010