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OXiGENE announces ZYBRESTAT Phase 2/3 study results at ESMO Congress

OXiGENE, a clinical-stage, biopharmaceutical company developing novel therapeutics to treat cancer and eye diseases, announced that an ongoing analysis of positive results reported earlier from a randomized, controlled, Phase 2/3 study of ZYBRESTAT (fosbretabulin, CA4P) were presented today at the 35th European Society of Medical Oncology (ESMO) Congress in Milan, Italy by Julie Ann Sosa, M.D., F.A.C.S., of Yale University.

11 Oct 2010

First Edition: October 11, 2010

Today's early morning highlights include articles on new options for open season, concerns among retirees about the provisions of the federal health law and the latest campaign arguments over that new overhaul.

11 Oct 2010

TTF therapy with chemotherapy increases survival time in patients with non-small cell lung cancer

Novocure reported today that patients with advanced non-small cell lung cancer (NSCLC) achieved a significant increase in survival time when tumor treating fields (TTF) therapy was added to chemotherapy, as compared to previously reported outcomes for patients receiving chemotherapy alone.

11 Oct 2010

NIH awards La Jolla Institute $12.6M to develop San Diego's first Center for RNAi screening

The La Jolla Institute for Allergy & Immunology will develop San Diego's first Center for RNAi screening -- a breakthrough genomics technology that will further enhance San Diego's reputation as a national research leader and provide the local biomedical community ready access to the Nobel-Prize winning technology.

11 Oct 2010

Afinitor-Sandostatin LAR Depot combination extends median PFS in patients with advanced carcinoid tumors

A Novartis Pharmaceuticals Corporation Phase III study of Afinitor® (everolimus) tablets in combination with Sandostatin® LAR Depot (octreotide acetate for injectable suspension) extended median progression-free survival (PFS), or time without tumor growth, in patients with advanced carcinoid tumors compared to taking octreotide LAR alone.

11 Oct 2010

ESMO and Thomson Reuters launch unique portal for oncologists

A unique portal, offering oncologists access to the latest information in the field of cancer research, will be launched in 2011 by the European Society for Medical Oncology (ESMO) in association with Thomson Reuters. The announcement was made today at the 35th ESMO Congress taking place from 8 to 12 October, in Milan, Italy.

11 Oct 2010

New natural dietary components inhibit breast cancer cells

Researchers at Indiana University and Methodist Research Institute have published the dramatic effects of a natural formula against breast cancer. The impressive results are found in the most recent publication of Integrative Cancer Therapies. Lead investigator Dr. Daniel Sliva says, The formula we studied inhibits growth of highly metastatic human breast cancer cells, and suppresses metastatic potential of these cells.

11 Oct 2010

$Balloon kyphoplasty offers effective relief for debilitating spinal fractures suffered by metastatic cancer patients$

Balloon kyphoplasty offers effective relief for debilitating spinal fractures suffered by metastatic cancer patients

A surgical technique appears to offer quick and effective relief for debilitating spinal fractures often suffered by patients with metastatic cancer, researchers reported at the 35th Congress of the European Society for Medical Oncology (ESMO) in Milan.

11 Oct 2010

Combination of MET and erlotinib delays lung cancer progression: Study

A subset of lung cancer patients seem to live longer and experience delays in disease progression when a new drug that targets a cancer-associated molecule called MET is added to treatment with erlotinib, the results of a double-blind Phase-II trial show.

11 Oct 2010

Promising clinical data of ImmunoGen's lorvotuzumab mertansine to be presented at ESMO conference

ImmunoGen, Inc., a biopharmaceutical company that develops targeted anticancer therapeutics using its Targeted Antibody Payload (TAP) technology, today announced the presentation of encouraging clinical data for the Company's lorvotuzumab mertansine (IMGN901) targeted anticancer compound at the 35th European Society for Medical Oncology (ESMO) Conference being held in Milan, Italy, October 8-12, 2010.

11 Oct 2010

Millennium, Seattle Genetics announce positive top-line results of SGN-35 phase II clinical trial

Seattle Genetics, Inc. and Millennium The Takeda Oncology Company, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, today announced positive top-line results from a phase II clinical trial of single-agent brentuximab vedotin (SGN-35), an antibody-drug conjugate (ADC) targeted to CD30. The trial was conducted in 58 relapsed or refractory systemic anaplastic large cell lymphoma (ALCL) patients.

11 Oct 2010

Seattle Genetics reports SGN-75 phase I clinical trial data

Seattle Genetics, Inc. today reported data from a phase I clinical trial of SGN-75 in patients with non-Hodgkin lymphoma or renal cell carcinoma (RCC). Preliminary results demonstrate tolerability and antitumor activity, including two objective responses in the first 16 patients treated. Dose-escalation is continuing.

11 Oct 2010

CCHIT certifies Health Care Systems' eMR Version 4

Health Care Systems, Inc. (HCS) announced today that HCS eMR, Version 4, is 2011/2012 compliant and was certified as an EHR Module on 9/30/2010 by the Certification Commission for Health Information Technology (CCHIT®), an ONC-ATCB, in accordance with the applicable HOSPITAL certification criteria adopted by the Secretary of Health and Human Services. The 2011/2012 criteria support the Stage 1 meaningful use measures required to qualify eligible providers and hospitals for funding under the American Recovery and Reinvestment Act (ARRA).

11 Oct 2010

Rutgers University receives NIH grant to increase reliability of prostate cancer imaging

The National Institutes of Health has awarded a $3.3 million grant to a research team that includes Rutgers University to increase the reliability of imaging prostate cancer.

11 Oct 2010

GSU professor receives USDA grant to study dynamics of childhood obesity

A Georgia State University professor has received a U.S. Department of Agriculture grant to look at the obesity trends from childhood to adolescence.

11 Oct 2010

FDA issues CRL for AZ-004 NDA application

Alexza Pharmaceuticals, Inc. announced today that it has received a Complete Response Letter (CRL) from the U.S. Food and Drug Administration (FDA or Agency) regarding its New Drug Application (NDA) for AZ-004 (Staccato loxapine), submitted as Adusuve Staccato (loxapine) inhalation aerosol, 5 mg and 10 mg.

11 Oct 2010

Financing HIV/AIDS prevention, treatment could cost $400B-$700B over 20 years

A new report published by the Results for Development Institute in the Lancet "has offered governments and donors a glimpse into the future of HIV epidemics - and what it will cost to prevent and treat them. Researchers warn of hard choices ahead and a need for some countries to take more responsibility for their national programmes," IRIN/PlusNews reports. Study authors present their "cheapest" and "ideal" scenarios for HIV/AIDS funding in the future, according to IRIN/PlusNews.

11 Oct 2010

Researchers develop new approach to treat inflammatory bowel disease

Researchers at the Georgia Institute of Technology and Emory University have developed a novel approach for delivering small bits of genetic material into the body to improve the treatment of inflammatory bowel diseases. Delivering short strands of RNA into cells has become a popular research area because of its potential therapeutic applications, but how to deliver them into targeted cells in a living organism has been an obstacle.

11 Oct 2010

Auxilium commences dosing in global XIAFLEX phase III program for Peyronie's disease

Auxilium Pharmaceuticals, Inc., a specialty biopharmaceutical company, today announced that the first subject has been dosed in the global phase III program of XIAFLEX® for the treatment of Peyronie's disease. Peyronie's disease is the development of scar tissue on the penis that can cause the penis to curve during erection, often interfering with or preventing intercourse and resulting in psychological distress or bother for the patient.

11 Oct 2010

Study to uncover genetic basis of obesity

An international consortium has made significant inroads into uncovering the genetic basis of obesity by identifying 18 new gene sites associated with overall obesity and 13 that affect fat distribution. The studies include data from nearly a quarter of a million participants, the largest genetic investigation of human traits to date.

11 Oct 2010

Medical News

OXiGENE announces ZYBRESTAT Phase 2/3 study results at ESMO Congress

First Edition: October 11, 2010

TTF therapy with chemotherapy increases survival time in patients with non-small cell lung cancer

NIH awards La Jolla Institute $12.6M to develop San Diego's first Center for RNAi screening

Afinitor-Sandostatin LAR Depot combination extends median PFS in patients with advanced carcinoid tumors

ESMO and Thomson Reuters launch unique portal for oncologists

New natural dietary components inhibit breast cancer cells

Balloon kyphoplasty offers effective relief for debilitating spinal fractures suffered by metastatic cancer patients

Combination of MET and erlotinib delays lung cancer progression: Study

Promising clinical data of ImmunoGen's lorvotuzumab mertansine to be presented at ESMO conference

Millennium, Seattle Genetics announce positive top-line results of SGN-35 phase II clinical trial

Seattle Genetics reports SGN-75 phase I clinical trial data

CCHIT certifies Health Care Systems' eMR Version 4

Rutgers University receives NIH grant to increase reliability of prostate cancer imaging

GSU professor receives USDA grant to study dynamics of childhood obesity

FDA issues CRL for AZ-004 NDA application

Financing HIV/AIDS prevention, treatment could cost $400B-$700B over 20 years

Researchers develop new approach to treat inflammatory bowel disease

Auxilium commences dosing in global XIAFLEX phase III program for Peyronie's disease

Study to uncover genetic basis of obesity

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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