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Toxic protein in bee venom improves liposome encapsulated drug effectiveness

The next time you are stung by a bee, here's some consolation: a toxic protein in bee venom, when altered, significantly improves the effectiveness liposome-encapsulated drugs or dyes, such as those already used to treat or diagnose cancer. This research, described in the August 2010 print issue of the FASEB Journal, shows how modified melittin may revolutionize treatments for cancer and perhaps other conditions, such as arthritis, cardiovascular disease, and serious infections.

3 Aug 2010

Antisense Pharma receives FDA IND authorisation for clinical studies with trabedersen for high-grade glioma

The biopharmaceutical company Antisense Pharma announced today that the US-American Food and Drug Administration (FDA) has issued an Investigational New Drug (IND)-authorisation for clinical studies with trabedersen for patients with high-grade glioma. This authorisation entitles the company to include US-American clinics both in the phase III study SAPPHIRE and in further studies.

3 Aug 2010

New, improved ClinicTools now available

The new and improved ClinicTools is deployed. Physicians can send error-free prescriptions, including test orders, electronically. Pharmacies, labs and diagnostic centers can now register for free to increase their respective business. ClinicTools started out as simply an electronic medical record platform for healthcare providers.

3 Aug 2010

New surgical technique to maximize preservation of periprostatic anatomy

Stress urinary incontinence is one of the most feared complications of radical prostatectomy. The weighted mean continence rate immediately after catheter removal following robot-assisted laparoscopic radical prostatectomy (RALP) is 25.7%. Evidently, early recovery of urinary continence remains a challenge to be overcome. The Surgery in Motion section of the September issue of European Urology describes the surgical steps of pubovesical complex (PVC)-sparing RALP and presents the preliminary results of the technique.

3 Aug 2010

Obama Administration releases U.S. MDGs strategy

Obama Administration officials on Friday unveiled the U.S. government's strategy to achieve the U.N. Millennium Development Goals by 2015 during a meeting at the U.N. Foundation "that was closed to the press," Washington Post's "Checkpoint Washington" blog reports.

3 Aug 2010

Pennsylvania to open high-risk insurance program for uninsured individuals with pre-existing medical conditions

As part of the national health insurance reform, Pennsylvania this week will open a high-risk insurance program for uninsured individuals who have pre-existing medical conditions, Insurance Commissioner Joel Ario said today.

3 Aug 2010

Study shows prevalence, severity of dyspnea in long-term lung cancer survivors

With the growing number of long-term lung cancer survivors, research is needed to identify and address cancer survivorship issues. One of the most common and debilitating symptoms among lung cancer patients is dyspnea, or shortness of breath. As most studies of dyspnea have reviewed patients with active lung cancer or immediately after treatment, the prevalence of dyspnea over the long-term once treatment has been completed is not well characterized.

3 Aug 2010

Telormedix, Swiss TPH Institute collaborate to develop effective vaccines for Malaria, Buruli Ulcer

Telormedix, a clinical stage biopharmaceutical company using targeted immunity to treat cancer and other diseases, today announced the start of a collaboration with the Swiss Tropical and Public Health Institute (Swiss TPH) on a pilot study using Telormedix's adjuvant, TMX-201, in connection with immunization for Malaria and Buruli Ulcer.

3 Aug 2010

IU receives NSF awards to lead two high-speed international network services

Indiana University has been awarded $9.2 million from the National Science Foundation to lead two high-speed international network services. The awards provide IU with $4.6 million to continue the TransPAC3 network connection to Asia, and an additional $4.6 million for a new connection to Europe, named ACE -- America Connects to Europe.

3 Aug 2010

Menstrual cycle affects body's response to tracheal intubation: Research

In women undergoing surgery, the heart rate and blood pressure response to ventilation tube placement varies at different times of the menstrual cycle, according to a study in the August issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

3 Aug 2010

Way patients cope with diabetes-related foot ulcers and their levels of depression affect wound healing

People suffering from diabetes-related foot ulcers show different rates of healing according to the way they cope and their psychological state of mind, according to new research by a health psychologist at The University of Nottingham.

3 Aug 2010

White House report predicts immediate health law benefits for Medicare's solvency; GOP lawmaker reacts

In a report released Monday, the Obama administration said "[t]he new health overhaul law will start producing savings for Medicare right away, and over time add 12 years of solvency to the program's giant trust fund for inpatient care." According to the report, Medicare savings by the end of next year will tally about $8 billion. Savings for rest of the decade would be an estimated $575 billion.

3 Aug 2010

Particles of iron oxide enhance tumor visibility through MRI

Tiny particles of iron oxide could become tools for simultaneous tumor imaging and treatment, because of their magnetic properties and toxic effects against brain cancer cells. In mice, researchers from Emory University School of Medicine have demonstrated how these particles can deliver antibodies to implanted brain tumors, while enhancing tumor visibility via magnetic resonance imaging (MRI).

3 Aug 2010

Sense of community is more important for pregnant woman's mental health than ethnicity: Study

It takes a village to keep a pregnant woman at her healthiest, a new University of Michigan study shows. The study compared African American and European American women and women of lower and higher socioeconomic status to see what effects communalism, or a strong sense of community, had on African American women and women of lower socioeconomic status.

3 Aug 2010

PHD1 useful for pharmacologic inhibition in IBD: Research

Research into inflammatory bowel disease (IBD) led by UCD Conway Institute scientists with national and international collaborators has identified a key regulator involved in maintaining the functional integrity of the gut lining. The findings, published recently in the scientific journal, Gastroenterology, provide information that may be important in developing a new therapeutic approach to the treatment of the disease.

3 Aug 2010

Exercise, restricted-calorie diets help to stave off mental, physical degeneration of aging: Research

Harvard University researchers have uncovered a mechanism through which caloric restriction and exercise delay some of the debilitating effects of aging by rejuvenating connections between nerves and the muscles that they control.

3 Aug 2010

ArQule, Daiichi Sankyo announce decision to advance ARQ 197 into Phase 3 clinical trial for NSCLC

ArQule, Inc. and Daiichi Sankyo Co., Ltd. today announced that they will move forward with a Phase 3 clinical trial of ARQ 197, a small molecule inhibitor of the c-Met receptor tyrosine kinase, in patients with non-small cell lung cancer (NSCLC). In connection with this decision, the sponsor company, Daiichi Sankyo, will file a Special Protocol Assessment (SPA) with the U.S. Food and Drug Administration (FDA) for a trial comparing ARQ 197 plus erlotinib against erlotinib plus placebo.

3 Aug 2010

Using internet can develop depression among teens

Teens who use the Internet pathologically appear more likely to develop depression than those who do not, according to a report posted online today that will appear in the October print issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

3 Aug 2010

Diffusion Pharmaceuticals receives patent for drug formulation

Diffusion Pharmaceuticals LLC, a clinical-stage drug-development company, today announced that the U.S. Patent and Trademark Office (USPTO) has granted it patent no. 7,759,506 entitled "Bipolar Trans Carotenoid Salts and Their Uses." This patent includes drug formulation and use claims relating to Diffusion's entire family of first-in-class new chemical entities. Diffusion Pharmaceuticals is commercializing this family of first-in-class drug candidates to treat serious or life-threatening medical conditions characterized by hypoxia or oxygen deprivation at the cellular level.

3 Aug 2010

Enzo Clinical Labs appointed as participating laboratory in Empire BlueCross BlueShield provider network

Enzo Biochem Inc.'s wholly-owned subsidiary, Enzo Clinical Labs, Inc., and Empire BlueCross BlueShield, the largest health insurer in New York State, today jointly announced that effective August 1, 2010 Enzo Clinical Labs will be a participating laboratory in the Empire provider network for the metropolitan New York area.

3 Aug 2010

Medical News

Toxic protein in bee venom improves liposome encapsulated drug effectiveness

Antisense Pharma receives FDA IND authorisation for clinical studies with trabedersen for high-grade glioma

New, improved ClinicTools now available

New surgical technique to maximize preservation of periprostatic anatomy

Obama Administration releases U.S. MDGs strategy

Pennsylvania to open high-risk insurance program for uninsured individuals with pre-existing medical conditions

Study shows prevalence, severity of dyspnea in long-term lung cancer survivors

Telormedix, Swiss TPH Institute collaborate to develop effective vaccines for Malaria, Buruli Ulcer

IU receives NSF awards to lead two high-speed international network services

Menstrual cycle affects body's response to tracheal intubation: Research

Way patients cope with diabetes-related foot ulcers and their levels of depression affect wound healing

White House report predicts immediate health law benefits for Medicare's solvency; GOP lawmaker reacts

Particles of iron oxide enhance tumor visibility through MRI

Sense of community is more important for pregnant woman's mental health than ethnicity: Study

PHD1 useful for pharmacologic inhibition in IBD: Research

Exercise, restricted-calorie diets help to stave off mental, physical degeneration of aging: Research

ArQule, Daiichi Sankyo announce decision to advance ARQ 197 into Phase 3 clinical trial for NSCLC

Using internet can develop depression among teens

Diffusion Pharmaceuticals receives patent for drug formulation

Enzo Clinical Labs appointed as participating laboratory in Empire BlueCross BlueShield provider network

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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