Posted in | Life Sciences

What the past, present and future of DMPK reveal about drug development

This seasonal episode of the Pharmaron DMPK Insights Podcast Series is inspired by Charles Dickens’ novella “A Christmas Carol.”

Phil Jeffrey (Senior Vice President of Preclinical Development at Bicycle Therapeutics with over 35 years in the DMPK field), Beth Williamson (Head of ADME in the DMPK group at UCB), and Daniel Price (Vice President of Computational Chemistry & Structural Biology at Nimbus Therapeutics) discuss DMPK’s past, present, and future with Scott Summerfield (Executive Director of Metabolism at Pharmaron). 

The host and guests cover a range of topics, including the evolution of DMPK as a predictive discipline able to better link the chemistry of drug design with the biology of drug disposition and effect.

Other areas of discussion include:

  • The founding names and principles of DMPK
  • The emergence of Discovery DMPK
  • Current technology use and in silico modeling
  • DMPK’s role in the three pillars/5Rs and PK/PD
  • The future of improved prediction thanks to developments in AI/ML

Acknowledgments

Produced from materials originally authored by Pharmaron Beijing Co., Ltd.

About Pharmaron

Pharmaron (Stock Code: 300759.SZ/3759.HK) is a premier R&D service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities, and established a broad spectrum of research, development and manufacturing service capabilities throughout the entire drug discovery, preclinical and clinical development process across multiple therapeutic modalities, including small molecules, biologics and CGT products. With over 17,000 employees, and operations in China, the U.S., and the U.K., Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan and China.


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