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Amgen announces PRIME '203' and '181' Phase 3 trial results

Amgen today announced that results from the PRIME '203' and '181' pivotal Phase 3 trials evaluating Vectibix (panitumumab) in combination with chemotherapy (FOLFOX or FOLFIRI) as a first and second-line treatment for metastatic colorectal cancer (mCRC), respectively, were published online in the Journal of Clinical Oncology.

5 Oct 2010

Research finds link between calcium and cancer

A protein that pumps calcium out of cells also moonlights as a signal to get massive quantities of the stuff to flow in, according to Johns Hopkins scientists. Their discovery of this surprisingly opposite function, reported Oct. 1 in Cell, highlights the link between calcium and cancer and holds the promise of a new therapeutic target for certain breast cancers.

5 Oct 2010

CHI submits comments to FDA CDRH 510(k) Working Group Preliminary Report and Recommendations

California Healthcare Institute today submitted formal comments to the U.S. Food and Drug Administration (FDA) regarding the Center for Devices and Radiological Health 510(k) Working Group Preliminary Report and Recommendations, which could transform the 510(k) regulatory process for new medical devices, greatly affecting innovation and public health in California. CHI is a non-profit public policy research organization, representing leading California academic institutions, biotechnology, medical device, diagnostics and pharmaceutical firms.

5 Oct 2010

New biomarkers could lead to personalized radiation treatments for cancer patients

Mayo Clinic researchers have discovered biomarkers that could lead to personalized radiation treatments for cancer patients. The findings appear today online in the journal Genome Research.

5 Oct 2010

Global malaria control funding has gone up significantly since 2007, but funding shortfall remains, study says

Global malaria funding has gone up by 166 percent since 2007, but total funding is still 60 percent short of the $4.9 billion required for comprehensive malaria control this year, according to a study published in the journal Lancet on Saturday, Agence France-Presse reports.

5 Oct 2010

Depressed pregnant women at increased risk of delivering preterm birth and low-birth weight infants

Clinical depression puts pregnant women at increased risk of delivering prematurely and of giving birth to below-normal weight infants, according to a report published Oct. 4 in the Archives of General Psychiatry.

5 Oct 2010

Gentel Biosciences, RayBiotech to develop antibody array products with APiX chromogenic detection platform

Gentel Biosciences, a leader in proteomics profiling tools and RayBiotech, Inc., a pioneer and leader in protein and antibody array technologies, jointly announce today their partnership to develop and market RayBiotech's vast collection of antibody array products covering a wide variety of cytokines and other proteins for use with Gentel's APiX chromogenic detection platform.

5 Oct 2010

Study supports therapeutic potential of deep brain stimulation in patients with chronic psychiatric disorders

Using electrodes to stimulate areas deep within the brain may have therapeutic potential for patients with obsessive compulsive disorder that is refractory to treatment, according to a report in the October issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

5 Oct 2010

Study could lead to new therapies for acute muscle injury

A new research study published in The FASEB Journal may change how sports injuries involving muscle tissue are treated, as well as how much patient monitoring is necessary when potent anti-inflammatory drugs are prescribed for a long time. That's because the study shows for the first time that inflammation actually helps to heal damaged muscle tissue, turning conventional wisdom on its head that inflammation must be largely controlled to encourage healing.

5 Oct 2010

Researchers discover therapy for treating terminal stages of cancer

For the first time ever, researchers have discovered a therapy that can effectively treat the now invariably lethal, terminal stages of cancer in animals. The study appears in the latest issue of the Proceedings of the National Academy of Sciences.

5 Oct 2010

New bill aims to promote federal agency collaboration on foreign aid, national security

House lawmakers recently introduced the 2010 Interagency National Security Professional Education, Administration and Development System Act in an effort to promote better "collaboration among federal agencies supporting security missions and foreign aid operations overseas," Government Executive reports.

5 Oct 2010

Media examines PEPFAR hearing, calls for more HIV funding ahead of Global Fund replenishment meeting

Ahead of the replenishment meeting for the Global Fund to Fight AIDS, Tuberculosis and Malaria, which kicks off today in New York, Inter Press Service examines the Obama administration's HIV/AIDS funding commitments.

5 Oct 2010

Human growth hormone can treat cystic fibrosis symptoms

Human growth hormone can be used successfully to treat some symptoms of cystic fibrosis, but its impact on the disease itself remains unknown, according to a new report funded by HHS' Agency for Healthcare Research and Quality (AHRQ).

5 Oct 2010

Researchers identify new type of cell that protects from immune system attack

Researchers at the Dana-Farber Cancer Institute in Boston have identified a new type of cell in mice that dampens the immune system and protects the animal's own cells from immune system attack.

5 Oct 2010

African leaders to meet in Zambia to discuss country responses to HIV/AIDS

Later this month, "[f]our former heads of state and other high-level African leaders who are the champions for a HIV/AIDS-free generation project" will travel to Zambia at the request of Zambian President Rupiah Banda for a meeting to discuss ways to strengthen the HIV/AIDS response in Africa, Times of Zambia/allAfrica.com reports.

5 Oct 2010

Reduced levels of brain-derived neurotrophic factor are a trait marker for psychogenic non-epileptic seizures

New research from Rhode Island Hospital found that reduced levels of brain-derived neurotrophic factor (BDNF), a protein in the brain that encourages growth of neurons, may be a trait marker for individuals with psychogenic non-epileptic seizures (PNES) (seizures that are psychological in origin). The findings are published in the October 4, 2010, issue of Neurology, the medical journal of the American Academy of Neurology.

5 Oct 2010

Aeras Global receives FDA grant to develop biomarkers for TB vaccine

The Aeras Global TB Vaccine Foundation is pleased to announce receipt of a grant from the United States Food and Drug Administration (FDA) to develop new biological and immunological biomarkers for TB vaccine development. The FDA grant, which supports the coordination of a multi-investigator project with researchers from the United States, the United Kingdom and South Africa, will provide $362,102 in the first year of funding.

5 Oct 2010

Elsevier launches new journal on neuroscience

Elsevier, a world-leading publisher of scientific, technical and medical information products and solutions, is pleased to announce the launch of a new journal, Developmental Cognitive Neuroscience.

5 Oct 2010

FDA awards $2.9 million to support tuberculosis research projects

The U.S. Food and Drug Administration today announced the award of $2.9 million to support six research projects that will help with the diagnosis, treatment, and prevention of tuberculosis (TB).

5 Oct 2010

NIH awards contract to develop nanotechnology tools for atherosclerosis treatment

Georgia Tech and Emory University have received a five-year $14.6 million contract from the National Institutes of Health (NIH) to continue the development of nanotechnology and biomolecular engineering tools and methodologies for detecting and treating atherosclerosis.

5 Oct 2010

Research News and Research

Amgen announces PRIME '203' and '181' Phase 3 trial results

Research finds link between calcium and cancer

CHI submits comments to FDA CDRH 510(k) Working Group Preliminary Report and Recommendations

New biomarkers could lead to personalized radiation treatments for cancer patients

Global malaria control funding has gone up significantly since 2007, but funding shortfall remains, study says

Depressed pregnant women at increased risk of delivering preterm birth and low-birth weight infants

Gentel Biosciences, RayBiotech to develop antibody array products with APiX chromogenic detection platform

Study supports therapeutic potential of deep brain stimulation in patients with chronic psychiatric disorders

Study could lead to new therapies for acute muscle injury

Researchers discover therapy for treating terminal stages of cancer

New bill aims to promote federal agency collaboration on foreign aid, national security

Media examines PEPFAR hearing, calls for more HIV funding ahead of Global Fund replenishment meeting

Human growth hormone can treat cystic fibrosis symptoms

Researchers identify new type of cell that protects from immune system attack

African leaders to meet in Zambia to discuss country responses to HIV/AIDS

Reduced levels of brain-derived neurotrophic factor are a trait marker for psychogenic non-epileptic seizures

Aeras Global receives FDA grant to develop biomarkers for TB vaccine

Elsevier launches new journal on neuroscience

FDA awards $2.9 million to support tuberculosis research projects

NIH awards contract to develop nanotechnology tools for atherosclerosis treatment

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