Laboratory News and Research

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Researchers uncover one way breast cancer tumors resist vital medication

A team of Case Western Reserve University School of Medicine cancer researchers has uncovered one way certain tumors resist vital medication.

11 Aug 2016

Researchers develop new strategy to convert fibroblasts directly into neuronal cells

Researchers have used CRISPR -- a revolutionary new genetic engineering technique -- to convert cells isolated from mouse connective tissue directly into neuronal cells.

11 Aug 2016

Scientists activate neurons in the mouse brain by injecting virus containing light-sensitive proteins

Neurons that fire together really do wire together, says a new study in Science, suggesting that the three-pound computer in our heads may be more malleable than we think.

11 Aug 2016

Scientists provide new insights into workings of cancer-linked potassium channel

Most cells in the body carry on their surface tiny pores through which potassium ions travel. In controlling the flow of these positively charged ions, the channel helps the cell maintain its electrical balance.

11 Aug 2016

Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases

Many cancers only become a mortal danger if they form metastases elsewhere in the body. Such secondary tumours are formed when individual cells break away from the main tumour and travel through the bloodstream to distant areas of the body.

11 Aug 2016

Pancreatic cancer cells find alternative source of nutrition to avoid starvation

Pancreatic cancer cells avert starvation in dense tumors by ordering nearby support cells to supply them with an alternative source of nutrition.

11 Aug 2016

Integration of multiple types of protein biomarkers improves ability to detect breast cancer

A first-time study published in PLOS ONE shows that a combined assessment of multiple types of protein biomarkers in the blood offers an important advancement for detecting early breast cancer.

11 Aug 2016

Mayo Clinic launches new blood test that measures plasma ceramides to predict risk for heart disease

Mayo Clinic has launched a new type of blood test that will be used to predict adverse cardiovascular events in patients with progressing coronary artery disease (CAD).

11 Aug 2016

Novel PET radiotracer reveals epigenetic activity in the human brain for the first time

A novel PET radiotracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital is able for the first time to reveal epigenetic activity - the process that determines whether or not genes are expressed - within the human brain.

11 Aug 2016

Cutting off fuel to cancer cells may be potential therapeutic strategy for Kras-driven lung cancers

Research from investigators at Rutgers Cancer Institute of New Jersey and Princeton University has identified a new approach to cancer therapy in cutting off a cancer cell's 'fuel supply' by targeting a cellular survival mechanism known as autophagy.

11 Aug 2016

SBP board member donates $1M for researchers to study pancreatic and prostate cancer

Sanford Burnham Prebys Medical Discovery Institute (SBP) has received a $1M donation from The Epstein Family Foundation for scientists to study pancreatic and prostate cancer.

10 Aug 2016

Study shows 1 in 5 hospitalized adults discharged with vital sign instabilities

Twenty percent of people hospitalized are released before all vital signs are stable, a pattern that is associated with an increased risk of death and hospital readmission, a new study by UT Southwestern Medical Center researchers shows

10 Aug 2016

SLCU research institute uses Quorum PP3010T Cryo-SEM preparation system for plant biology research

Quorum Technologies, market and technology leaders in electron microscopy coating and cryogenic preparation products, report on plant biology research at the Sainsbury Laboratory, Cambridge UK, where their PP3010T Cryo-SEM preparation system is in routine use.

10 Aug 2016

Rare genetic variations linked to severe porphyria

An international research team has linked rare variations in a cell membrane protein to the wide variation in symptom severity that is a hallmark of porphyria, a rare disorder that often affects the skin, liver and nervous system.

10 Aug 2016

Understanding brain circuit development: an interview with Dr Hollis Cline

There's a tremendous amount known about brain circuit development. Our work was inspired by experiments that were done over 50 years ago by scientists at Harvard University, Hubel and Wiesel. They received a Nobel Prize for their work and have inspired many additional experiments over the last 50 or 60 years.

10 Aug 2016

UCLA study suggests lower BPS doses damage woman's egg cells

Bisphenol S, a chemical used to manufacture polycarbonate water bottles and many other products such as epoxy glues and cash receipts, is an increasingly common replacement for bisphenol A, the of which was discontinued because of concerns about its harmful effects on the reproductive system.

10 Aug 2016

Industrial chemicals exceed safety levels in public drinking water supplies for 6 million Americans

Levels of a widely used class of industrial chemicals linked with cancer and other health problems--polyfluoroalkyl and perfluoroalkyl substances (PFASs)--exceed federally recommended safety levels in public drinking water supplies for six million people in the U.S., according to a new study led by researchers from Harvard T.H. Chan School of Public Health and the Harvard John A. Paulson School of Engineering and Applied Sciences.

10 Aug 2016

Whitehead Institute researchers identify cellular mechanisms involved in pre-mouth array formation

Whitehead Institute researchers have identified the pre-mouth array--an area of the developing face in embryonic frogs--that "unzips" to surround the mouth opening. Their work highlights the precision necessary to create the mouth and identifies the cellular mechanisms that drive its formation.

9 Aug 2016

Experts develop new genomic testing method for pulmonary hypertension caused by genetic mutation

Pulmonology and genetics experts from two Utah healthcare organizations have collaboratively developed a new diagnostic genomic testing method for a rare form of pulmonary hypertension caused by a genetic mutation they discovered three years ago.

9 Aug 2016

Manganese-based antioxidant complex of Deinococcus protects mice from gamma radiation

They call it "Conan the Bacterium," and now it may be used to help save lives in the event of a nuclear disaster or terrorist attack.

9 Aug 2016

Laboratory News and Research

Researchers uncover one way breast cancer tumors resist vital medication

Researchers develop new strategy to convert fibroblasts directly into neuronal cells

Scientists activate neurons in the mouse brain by injecting virus containing light-sensitive proteins

Scientists provide new insights into workings of cancer-linked potassium channel

Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases

Pancreatic cancer cells find alternative source of nutrition to avoid starvation

Integration of multiple types of protein biomarkers improves ability to detect breast cancer

Mayo Clinic launches new blood test that measures plasma ceramides to predict risk for heart disease

Novel PET radiotracer reveals epigenetic activity in the human brain for the first time

Cutting off fuel to cancer cells may be potential therapeutic strategy for Kras-driven lung cancers

SBP board member donates $1M for researchers to study pancreatic and prostate cancer

Study shows 1 in 5 hospitalized adults discharged with vital sign instabilities

SLCU research institute uses Quorum PP3010T Cryo-SEM preparation system for plant biology research

Rare genetic variations linked to severe porphyria

Understanding brain circuit development: an interview with Dr Hollis Cline

UCLA study suggests lower BPS doses damage woman's egg cells

Industrial chemicals exceed safety levels in public drinking water supplies for 6 million Americans

Whitehead Institute researchers identify cellular mechanisms involved in pre-mouth array formation

Experts develop new genomic testing method for pulmonary hypertension caused by genetic mutation

Manganese-based antioxidant complex of Deinococcus protects mice from gamma radiation

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