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Liquid biopsy enables early, accurate identification of breast cancer patients with poor prognosis

Liquid biopsy can help to identify breast cancer patients with a poor prognosis earlier and more accurately than before, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

7 Oct 2021

Scientists identify a new method to treat triple-negative breast cancer

A team of clinicians and scientists from the National Cancer Centre Singapore (NCCS), Singapore General Hospital (SGH) and A*STAR's Genome Institute of Singapore (GIS) has identified a novel method to treat triple-negative breast cancer (TNBC). They discovered that cancer cells switch between different cell states and are able to change from being less aggressive ('epithelial') to being more aggressive ('mesenchymal'), and vice versa.

7 Oct 2021

Planar cell polarity pathway found to be responsible for the formation and maintenance of synapses

Within the brain and other parts of the nervous system, synapses are key junctional points in between neurons (the nerve cells) where critical signals are transmitted. More specifically, the "glutamatergic" synapses are the prime "excitatory" synapse junctions that neurons use to activate each other and are known to have broad diversity in size and shape.

7 Oct 2021

Massage can enhance healing and strength of muscles, study finds

Massage has been used to treat sore, injured muscles for more than 3,000 years, and today many athletes swear by massage guns to rehabilitate their bodies. But other than making people feel good, do these "mechanotherapies" actually improve healing after a severe injury? According to a new study from researchers at Harvard's Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engineering and Applied Sciences (SEAS), the answer is "yes."

7 Oct 2021

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Pairing a newly developed gel with immunotherapy that was delivered to post-surgical mouse brains with glioblastoma, a highly malignant and deadly cancer, improved the immunotherapy's effectiveness, report researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and colleagues. The findings appeared on Oct. 6, 2021, in Science Advances.

7 Oct 2021

Mouse brain atlas may help understand the complex circuits of the human brain

The circuits of the human brain contain more than 100 billion neurons, each linked to many other neurons via thousands of synaptic connections, resulting in a three-pound organ that is profoundly more complex than the sum of its innumerable parts.

7 Oct 2021

Study illuminates how BRD4 protein directs the spatial organization of DNA within cell nucleus

New research is advancing understanding of certain cancers and complex congenital disorders by illuminating how BRD4, a protein that scientists have studied for years, directs the spatial organization of DNA within the nucleus of the cell, a function critical for stem cell differentiation into muscle cells.

7 Oct 2021

Specialized cells that keep the heart beating have ability to regenerate after birth, study reveals

Specialized cells that conduct electricity to keep the heart beating have a previously unrecognized ability to regenerate in the days after birth, a new study in mice by UT Southwestern researchers suggests.

7 Oct 2021

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

A new study published on the medRxiv* preprint server focused on a patient with a persistent symptomatic viral infection for over a year. Researchers amplified sub-genomic transcripts for the E gene (sgE) using nasopharyngeal samples of the patient infected with SARS-CoV-2 over the course of 335 days.

6 Oct 2021

Tiny bubbles show promise for reducing inflammation

Scientists hope that tiny sacs of material excreted by cells - so-called extracellular vesicles - can be used to deliver drugs inside the body. Researchers at Karolinska Institutet now show that these nano-bubbles can transport protein drugs that reduce inflammation caused by different diseases.

6 Oct 2021

Scientists make inroads into creating an atlas of the mouse brain

It takes billions of cells to make a human brain, and scientists have long struggled to map this complex network of neurons.

6 Oct 2021

Neuroscientists unveil detailed atlas of brain cells

When you clicked to read this story, a band of cells across the top of your brain sent signals down your spine and out to your hand to tell the muscles in your index finger to press down with just the right amount of pressure to activate your mouse or track pad.

6 Oct 2021

Novel proteomics approach predicts severe COVID-19 outcomes

Researchers in the United States, Canada, and the UK have developed a potential new approach to predicting severe and critical outcomes among patients with coronavirus disease 2019 (COVID-19).

6 Oct 2021

Machine learning and high-powered microscopes provide detailed snapshots of cells' inner machinery

Open any introductory biology textbook, and you'll see a familiar diagram: A blobby-looking cell filled with brightly colored structures – the inner machinery that makes the cell tick.

6 Oct 2021

Graphene biosensor in a portable and wireless device for rapid SARS-CoV-2 detection

A new study posted to the medRxiv* server and led by Dr. Mattia D'Agostino, Dr. Eleonora Pavoni and Dr. Alice Romagnoli from the Polytechnic University of Marche in Ancona (Italy), a gFET biosensor that uses angiotensin-converting enzyme 2 (ACE2) as a bioreceptor has been put forth as a viable solution.

6 Oct 2021

Psychological therapy alleviates adverse biobehavioral effects in young adult testicular cancer survivors

Psychological therapy reduces the adverse biobehavioral effects of testicular cancer in young adult survivors, according to a pilot study led by the University of California, Irvine.

6 Oct 2021

Toxic fatty acids trigger cell death in damaged neurons

Cells that normally nourish healthy brain cells called neurons release toxic fatty acids after neurons are damaged, a new study in rodents shows.

6 Oct 2021

Detailed atlas of the mammalian primary motor cortex will provide a springboard for future research

The NIH Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative Cell Census Network (BICCN) has unveiled an atlas of cell types and an anatomical neuronal wiring diagram for the mammalian primary motor cortex, derived from detailed studies of mice, monkeys, and humans.

6 Oct 2021

Black NSCLC patients receiving immunotherapy have lower risk of death than white counterparts

Non-Hispanic Black patients with non-small cell lung cancer (NSCLC) who were treated with immunotherapy had a lower risk of death than their non-Hispanic white counterparts treated with immunotherapy, according to results presented at the virtual 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held October 6-8, 2021.

6 Oct 2021

New understanding of cellular defects related to Cystic Fibrosis may pave the way for treatments

A team in the College of Medicine led by Drs. Juan Ianowski (PhD) and Julian Tam (MD) found that sodium transport is abnormal in lungs with CF.

6 Oct 2021

Cell News and Research

Liquid biopsy enables early, accurate identification of breast cancer patients with poor prognosis

Scientists identify a new method to treat triple-negative breast cancer

Planar cell polarity pathway found to be responsible for the formation and maintenance of synapses

Massage can enhance healing and strength of muscles, study finds

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Mouse brain atlas may help understand the complex circuits of the human brain

Study illuminates how BRD4 protein directs the spatial organization of DNA within cell nucleus

Specialized cells that keep the heart beating have ability to regenerate after birth, study reveals

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

Tiny bubbles show promise for reducing inflammation

Scientists make inroads into creating an atlas of the mouse brain

Neuroscientists unveil detailed atlas of brain cells

Novel proteomics approach predicts severe COVID-19 outcomes

Machine learning and high-powered microscopes provide detailed snapshots of cells' inner machinery

Graphene biosensor in a portable and wireless device for rapid SARS-CoV-2 detection

Psychological therapy alleviates adverse biobehavioral effects in young adult testicular cancer survivors

Toxic fatty acids trigger cell death in damaged neurons

Detailed atlas of the mammalian primary motor cortex will provide a springboard for future research

Black NSCLC patients receiving immunotherapy have lower risk of death than white counterparts

New understanding of cellular defects related to Cystic Fibrosis may pave the way for treatments

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