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Cetero Research launches series of scientific seminars to help researchers on clinical trial design

Cetero Research, the leading early-stage contract research organization (CRO), is launching a series of scientific seminars, "An Accelerated Path to Proof-of-Concept in Drug Development," designed to help pharmaceutical and biotechnology researchers learn the latest innovations in Phase I and IIa clinical trial designs.

3 Sep 2010

'Aspartame danger' myths

Heard the one about how aspartame single-handedly caused the Gulf War syndrome? In recent years, outlandish allegations – often spread via the Internet by individuals who have little scientific or medical expertise – have tried to link the low-calorie sweetener to every ailment ranging from Multiple Sclerosis and Parkinson's disease to cancer and weight gain. However, the overwhelming body of scientific evidence via more than three decades of research and over 200 studies demonstrate that aspartame is safe.

3 Sep 2010

Research on immune system can develop new therapy for inflammation, tumors

In two closely related studies, two teams of Scripps Research Institute scientists have discovered the underlying mechanisms that activate a type of immune cell in the skin and other organs. The findings may lead to the development of new therapies to treat inflammation, wounds, asthma, and malignant tumors.

3 Sep 2010

Millennium publishes article on MLN4924 pathway mechanism in lymphoma

Millennium, The Takeda Oncology Company today announced the publication of an article in the journal Blood describing the novel mechanism of action of MLN4924 through targeted pathway modulation in diffuse large B-cell lymphoma (DLBCL).

3 Sep 2010

First direct evidence that X-linked TLR7 gene promotes lupus in humans

Lupus Research Institute-funded researcher Betty Tsao, PhD, at the University of California Los Angeles has discovered that humans-males in particular-with a variant form of the immune receptor gene "Toll Like Receptor 7 (TLR7)" are at increased risk of developing the autoimmune disease systemic lupus erythematosus (lupus). This breakthrough finding offers renewed hope for developing more targeted treatments.

3 Sep 2010

Research finds immune system mechanism to minimize collateral damage

A study published today in the journal Science shows how our bodies try to minimise potential 'collateral damage' caused by our immune system when fighting infection. The research may also provide new clues to why cigarette smoke is a significant risk factor for developing diseases of the lung such as chronic bronchitis and emphysema.

3 Sep 2010

Avoidance of fluoride reduces anemia in pregnant women and decreases pre-term births

Fluoride avoidance reduced anemia in pregnant women, decreased pre-term births and enhanced babies' birth-weight, concludes leading fluoride expert, AK Susheela and colleagues, in a study published in Current Science (May 2010).

3 Sep 2010

New study finds additional link between Light At Night and cancer

A new study from the Center for Interdisciplinary Chronobiological Research at the University of Haifa has found an additional link between Light At Night (LAN) and cancer. This research joins a series of earlier studies carried out at the University of Haifa that also established the correlation. "High power light bulbs contribute more to 'environmental light pollution', which the study has shown is a carcinogenic pollution," notes Prof. Abraham Haim, who headed the study.

3 Sep 2010

Scientists identify thousands of proteins that play a key role in compacting DNA

Scientists have built a clearer picture of how lengthy strands of DNA are concertinaed when our cells grow and divide, in a discovery could help explain how cell renewal can go wrong.

3 Sep 2010

Study establishes critical roles for cancer-causing Myc gene in stem cell biology

Stem cells might be thought of as trunks in the tree of life. All multi-cellular organisms have them, and they can turn into a dazzling variety other cells-kidney, brain, heart or skin, for example. One class, pluripotent stem cells, has the capacity to turn into virtually any cell type in the body, making them a focal point in the development of cell therapies, the conquering of age-old diseases or even regrowing defective body parts.

3 Sep 2010

U.S. DOE's SRNL and Ukraine's IRL to collaborate on radiation ecology research

Under a recently signed agreement, the U.S. Department of Energy's (DOE) Savannah River National Laboratory (SRNL) and the Ukraine's International Radioecology Laboratory (IRL) will collaborate on radiation ecology research, including projects in the region impacted by the catastrophic accident at the Chernobyl Nuclear Power Plant 24 years ago. Researchers at IRL use the area around Chernobyl as an extensive laboratory for studying the effects of radioactive contamination and methods of decontamination.

3 Sep 2010

BARDA awards contract to develop treatment for ionizing radiation exposure

The U.S. Department of Health and Human Services' Biomedical Advanced Research and Development Authority (BARDA) today awarded a $153 million contract to Cellerant Therapeutics, Inc. of San Carlos, Calif., to continue developing a new way to treat an illness caused by exposure to high levels of ionizing radiation which can damage the body's cells - the type of radiation that would come from a nuclear blast.

3 Sep 2010

Two scientists behind suit to block stem-cell research funding speak with lawmakers

The Wall Street Journal: "The two scientists behind the lawsuit that has temporarily blocked federal funding for embryonic stem-cell research said Wednesday they were motivated by ethical objections to destroying human embryos for medical research. The scientists, James Sherley of Boston and Theresa Deisher of Seattle, had never met until this week, when they flew to Washington to confer with House and Senate aides and lobby against research using embryonic stem cells.

3 Sep 2010

Simple protocol for determining Gross Chromosomal Rearrangement mutation rates

A cell devotes a significant amount of effort to maintaining the stability of its genome, preventing the sorts of chromosomal rearrangements characteristic of many cancers. Assays that measure the rate of gross chromosomal rearrangements (GCRs) are needed in order to understand the individual genes and the different pathways that suppress genomic instability.

3 Sep 2010

Education and prevention strategies vital in addressing breast cancer in Mexican-origin women

Specific prevention and education strategies are needed to address breast cancer in Mexican-origin women in this country, according to a study at The University of Texas MD Anderson Cancer Center, which was published online in the journal Cancer.

3 Sep 2010

Fresh Market's 16th Annual Sidewalk Sale to benefit Juvenile Diabetes Research Foundation

The Fresh Market will hold its 16th annual "Hope Floats" Sidewalk Sale on September 10 through September 12, from 11:00 a.m. to 6:00 p.m. daily to benefit the Juvenile Diabetes Research Foundation (JDRF). The Fresh Market's stores, located in 20 states across the Southeast, Midwest, Mid-Atlantic and Northeast, will offer root beer floats, hot dogs, gourmet cookies and ice cream sundaes in exchange for a donation to JDRF in support of its mission to find a cure for diabetes and its complications.

3 Sep 2010

St. Jude Doctors and scientists work together to improve survival rates for childhood cancer

Survival rates overall for childhood cancer are almost 80 percent—a marked advance against a disease that was curable in only a small fraction of children 50 years ago. However, despite progress, pediatric cancer remains the leading cause of death due to disease among U.S. children older than 1 year of age.

3 Sep 2010

Study: Health law's tax credit for small business could affect millions

A new Commonwealth Fund report estimates that "about 16.6 million workers are employed by small businesses that are eligible for health insurance tax credits" under the new health law but only 3.4 million of them are at companies that will take advantage of the credits, The Washington Post reports, adding that those businesses already offer their employees health insurance.

3 Sep 2010

Iroko Cardio International Sàrl announces data on HDB dosing of tirofiban, abciximab in interventional cardiology

Iroko Cardio International Sàrl announces long-term, three-year, mortality data from the Phase III, open label, multi-national study comparing high-dose bolus (HDB) dosing of AGGRASTAT(tirofiban) (25mcg/kg bolus followed by a 0.15mcg/kg/min infusion for 18-24 hours) vs. ReoPro (abciximab) in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI), presented at the 2010 European Society of Cardiology Meeting in Stockholm, Sweden.

3 Sep 2010

Researchers identify two proteins in cellular response to mechanical stimulation

Scripps Research Institute scientists have identified two proteins with potential to be important targets for research into a wide range of health problems, including pain, deafness, and cardiac and kidney dysfunction.

3 Sep 2010

Research News and Research

Cetero Research launches series of scientific seminars to help researchers on clinical trial design

'Aspartame danger' myths

Research on immune system can develop new therapy for inflammation, tumors

Millennium publishes article on MLN4924 pathway mechanism in lymphoma

First direct evidence that X-linked TLR7 gene promotes lupus in humans

Research finds immune system mechanism to minimize collateral damage

Avoidance of fluoride reduces anemia in pregnant women and decreases pre-term births

New study finds additional link between Light At Night and cancer

Scientists identify thousands of proteins that play a key role in compacting DNA

Study establishes critical roles for cancer-causing Myc gene in stem cell biology

U.S. DOE's SRNL and Ukraine's IRL to collaborate on radiation ecology research

BARDA awards contract to develop treatment for ionizing radiation exposure

Two scientists behind suit to block stem-cell research funding speak with lawmakers

Simple protocol for determining Gross Chromosomal Rearrangement mutation rates

Education and prevention strategies vital in addressing breast cancer in Mexican-origin women

Fresh Market's 16th Annual Sidewalk Sale to benefit Juvenile Diabetes Research Foundation

St. Jude Doctors and scientists work together to improve survival rates for childhood cancer

Study: Health law's tax credit for small business could affect millions

Iroko Cardio International Sàrl announces data on HDB dosing of tirofiban, abciximab in interventional cardiology

Researchers identify two proteins in cellular response to mechanical stimulation

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